Search Results - "Xiong, Xifeng"
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Insights Into Amentoflavone: A Natural Multifunctional Biflavonoid
Published in Frontiers in pharmacology (22-12-2021)“…Amentoflavone is an active phenolic compound isolated from over 40 years. Amentoflavone has been extensively recorded as a molecule which displays…”
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Diversity roles of CHD1L in normal cell function and tumorigenesis
Published in Biomarker research (04-03-2021)“…Chromodomain helicase/ATPase DNA binding protein 1-like gene (CHD1L) is a multifunctional protein participated in diverse cellular processes, including…”
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Fibrochondrogenic differentiation potential of tendon-derived stem/progenitor cells from human patellar tendon
Published in Journal of orthopaedic translation (01-05-2020)“…Bone–tendon junction (BTJ) is a unique structure connecting tendon and bone through a fibrocartilage zone. Owing to its unique structure, the regeneration of…”
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CHD1L Promotes Neuronal Differentiation in Human Embryonic Stem Cells by Upregulating PAX6
Published in Stem cells and development (15-11-2017)“…Chromodomain helicase DNA-binding protein 1-like gene (CHD1L) was initially isolated as a candidate oncogene in hepatocellular carcinoma, and it has been…”
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Type II Collagen Sponges Facilitate Tendon Stem/Progenitor Cells to Adopt More Chondrogenic Phenotypes and Promote the Regeneration of Fibrocartilage-Like Tissues in a Rabbit Partial Patellectomy Model
Published in Frontiers in cell and developmental biology (16-07-2021)“…Objective Fibrocartilage transition zone (FC) is difficult to regenerate after surgical re-attachment of tendon to bone. Here, we investigated whether type II…”
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Prognostic Significance of the CXCLs and Its Impact on the Immune Microenvironment in Ovarian Cancer
Published in Disease markers (2023)“…The chemokine (C-X-C motif) ligand (CXCL) family in tumor tissue is closely related to tumor growth, metastasis, and survival. However, the differential…”
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Icariin inhibits the inflammation through down-regulating NF-κB/HIF-2α signal pathways in chondrocytes
Published in Bioscience reports (27-11-2020)“…Articular cartilage injury or defect is a common disease and is mainly characterized by cartilage degradation because of chondrocyte inflammation. By now,…”
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Extracellular vesicles derived from cervical cancer cells carrying MCM3AP-AS1 promote angiogenesis and tumor growth in cervical cancer via the miR-93/p21 axis
Published in Experimental cell research (15-07-2023)“…Tumor cells can promote angiogenesis by secreting extracellular vesicles (EVs). Meanwhile, tumor-derived EVs can carry long non-coding RNAs to activate…”
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Icariin increases chondrocyte vitality by promoting hypoxia-inducible factor-1α expression and anaerobic glycolysis
Published in The knee (01-01-2020)“…Articular cartilage is a unique avascular tissue in which chondrocytes are embedded in extracellular matrix (ECM). The decreased ECM resulting from the loss of…”
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Expression and Gene Regulation Network of Metabolic Enzyme Phosphoglycerate Mutase Enzyme 1 in Breast Cancer Based on Data Mining
Published in BioMed research international (2021)“…The metabolic enzyme phosphoglycerate mutase enzyme 1 (PGAM1) is a key enzyme in the glycolysis pathway, and glycolysis is closely related to cancer…”
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High expression of FUSE binding protein 1 in breast cancer stimulates cell proliferation and diminishes drug sensitivity
Published in International journal of oncology (01-08-2020)“…Breast cancer is the most common malignant tumor affecting women worldwide and is divided into the following subtypes: Luminal A, Luminal B, HER‑2…”
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GSK343 induces programmed cell death through the inhibition of EZH2 and FBP1 in osteosarcoma cells
Published in Cancer biology & therapy (03-03-2020)“…Enhancer of zeste homolog 2 (EZH2) is an important member of the epigenetic regulatory factor polycomb group proteins (PcG) and is abnormally expressed in a…”
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Icariin suppresses cell cycle transition and cell migration in ovarian cancer cells
Published in Oncology reports (01-04-2019)“…Ovarian cancer is the third most common type of gynecological tumor, in addition to being the most lethal. Cytoreductive surgery with chemotherapy is the…”
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Fuse-binding protein 1 is a target of the EZH2 inhibitor GSK343, in osteosarcoma cells
Published in International journal of oncology (01-08-2016)“…Osteosarcoma is the primary cancer of leaf tissue and is regarded as a differentiation disease caused by genetic and epigenetic changes which interrupt the…”
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FBP1 knockdown decreases ovarian cancer formation and cisplatin resistance through EZH2-mediated H3K27me3
Published in Bioscience reports (01-09-2022)“…Abstract Worldwide, ovarian cancer (OC) is the seventh common cancer and the second most common cause of cancer death in women. Due to high rates of relapse,…”
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Amentoflavone triggers cell cycle G2/M arrest by interfering with microtubule dynamics and inducing DNA damage in SKOV3 cells
Published in Oncology letters (01-11-2020)“…Ovarian cancer is the seventh most common cancer and the second most common cause of cancer-associated mortality among gynecological malignancies worldwide…”
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Protective effect of p53 on the viability of intervertebral disc nucleus pulposus cells under low glucose condition
Published in Biochemical and biophysical research communications (02-09-2017)“…P53 is a famous cancer suppressor and plays key roles in metabolism. Intervertebral disc (IVD) is the largest avascular cartilaginous structure in humans and…”
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Baicalin promotes chondrocyte viability and the synthesis of extracellular matrix through TGF-β/Smad3 pathway in chondrocytes
Published in American journal of translational research (01-01-2021)“…BACKGROUNDOsteoarthritis (OA) is common in the elderly. Baicalin (BA) is a flavonoid monomer extracted from Scutellaria baicalensis Georgi, which has been…”
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