Search Results - "Xiong, Junyuan"

Treatment of HCV with ABT-450/r–Ombitasvir and Dasabuvir with Ribavirin by Feld, Jordan J, Kowdley, Kris V, Coakley, Eoin, Sigal, Samuel, Nelson, David R, Crawford, Darrell, Weiland, Ola, Aguilar, Humberto, Xiong, Junyuan, Pilot-Matias, Tami, DaSilva-Tillmann, Barbara, Larsen, Lois, Podsadecki, Thomas, Bernstein, Barry

“…In this trial in previously untreated patients with HCV genotype 1 infection and no cirrhosis, high rates of sustained response were achieved with three new…”
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Retreatment of HCV with ABT-450/r–Ombitasvir and Dasabuvir with Ribavirin by Zeuzem, Stefan, Jacobson, Ira M, Baykal, Tolga, Marinho, Rui T, Poordad, Fred, Bourlière, Marc, Sulkowski, Mark S, Wedemeyer, Heiner, Tam, Edward, Desmond, Paul, Jensen, Donald M, Di Bisceglie, Adrian M, Varunok, Peter, Hassanein, Tarek, Xiong, Junyuan, Pilot-Matias, Tami, DaSilva-Tillmann, Barbara, Larsen, Lois, Podsadecki, Thomas, Bernstein, Barry

“…In this trial in patients with HCV genotype 1 infection and no cirrhosis who had previously been treated with peginterferon and ribavirin, retreatment with…”
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Avelumab in metastatic urothelial carcinoma after platinum failure (JAVELIN Solid Tumor): pooled results from two expansion cohorts of an open-label, phase 1 trial by Patel, Manish R, Ellerton, John, Infante, Jeffrey R, Agrawal, Manish, Gordon, Michael, Aljumaily, Raid, Britten, Carolyn D, Dirix, Luc, Lee, Keun-Wook, Taylor, Mathew, Schöffski, Patrick, Wang, Ding, Ravaud, Alain, Gelb, Arnold B, Xiong, Junyuan, Rosen, Galit, Gulley, James L, Apolo, Andrea B

“…The approval of anti-programmed death ligand 1 (PD-L1) and anti-programmed death 1 agents has expanded treatment options for patients with locally advanced or…”
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Phase field simulations on the rate‐ and grain‐size‐dependent crack propagation of polycrystalline NiTi shape memory alloy by Xiong, Junyuan, Xu, Bo, Kang, Guozheng

“…A three‐dimensional non‐isothermal phase field model of polycrystalline NiTi shape memory alloy (SMA) was established based on the Ginzburg–Landau's theory,…”
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Phase field simulation on the martensite transformation and reorientation toughening behaviors of single crystal NiTi shape memory alloy: Effects of crystalline orientation and temperature by Xiong, Junyuan, Xu, Bo, Kang, Guozheng

“…•The effects of martensite transformation (MT) toughening at different crystalline orientation are clarified.•The reasons for the change of phase…”
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Coupled crystal plasticity-phase field simulation of twin-twin interaction in magnesium by Hu, Jiachen, Xu, Bo, Xiong, Junyuan, Yu, Chao, Kang, Guozheng

“…•A crystal plasticity-twin coupled phase field model was established.•The twin propagation is promoted or inhibited due to twin-twin interactions.•The…”
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Improved elastocaloric effect of NiTi shape memory alloys via microstructure engineering: A phase field simulation by Xu, Bo, Xiong, Junyuan, Yu, Chao, Wang, Chong, Wang, Qingyuan, Kang, Guozheng

“…•A grain size dependent and thermo-mechanically coupled phase field model is newly proposed.•The effects of grain size, texture, gradient-nanograin and bimodal…”
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Progress in phase field modeling of functional properties and fracture behavior of shape memory alloys by Xu, Bo, Yu, Chao, Xiong, Junyuan, Hu, Jiachen, Kan, Qianhua, Wang, Chong, Wang, Qingyuan, Kang, Guozheng

“…Shape memory alloys (SMAs) have been widely employed in many engineering fields due to their unique functional properties, such as super-elasticity,…”
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Effect of Ni4Ti3 precipitates on the functional properties of NiTi shape memory alloys: A phase field study by Xu, Bo, Sun, Yuanzun, Yu, Chao, Hu, Jiachen, Zhu, Jiaming, Xiong, Junyuan, Kan, Qianhua, Wang, Chong, Wang, Qingyuan, Kang, Guozheng

“…•A phase field model coupling the precipitation of Ni4Ti3 and B2-B19′ martensite transformation is proposed.•The precipitate-dependent functional properties of…”
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Optimal decision‐making in oncology development programs based on probability of success for phase III utilizing phase II/III data on response and overall survival by Götte, Heiko, Xiong, Junyuan, Kirchner, Marietta, Demirtas, Hakan, Kieser, Meinhard

“…Summary In clinical development, there is a trade‐off between investment and level of confidence in the potential of the drug before going into phase III…”
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An Efficient Oncology Phase II/III Development Strategy Using Response and Overall Survival Information by Xiong, Junyuan

“…Cancer has a big impact on public health. The years of life and productivity lost to diseases and death, and the economic burden to the community make cancer a…”
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Avelumab treatment for metastatic urothelial carcinoma in the phase Ib JAVELIN Solid Tumor Study: Updated safety and efficacy analysis with ≥ two years of follow-up by Apolo, Andrea B., Ellerton, John Allan, Infante, Jeffrey R., Agrawal, Manish, Gordon, Michael S., Aljumaily, Raid, Britten, Carolyn D., Dirix, Luc, Lee, Keun-Wook, Taylor, Matthew H., Schoffski, Patrick, Wang, Ding, Ravaud, Alain, Xiong, Junyuan, Rosen, Galit, Gulley, James L., Patel, Manish R.

“…Abstract only 425 Background: Avelumab, a human anti‒PD-L1 IgG1 antibody, is approved for the treatment of metastatic urothelial cancer (mUC) progressing after…”
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A Comparative Study of Academic Networks in Computer Science and Physics by Xiong, Junyuan

“…Academic networks derived from research papers, in particular citation and co-author networks, have been studied widely. Although networks in an individual…”
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Updated efficacy and safety of avelumab in metastatic urothelial carcinoma (mUC): Pooled analysis from 2 cohorts of the phase 1b Javelin solid tumor study by Apolo, Andrea B., Ellerton, John Allan, Infante, Jeffrey R., Agrawal, Manish, Gordon, Michael S., Aljumaily, Raid, Britten, Carolyn D., Dirix, Luc Yves, Lee, Keun-Wook, Taylor, Matthew H., Schöffski, Patrick, Wang, Ding, Ravaud, Alain, Gelb, Arnold, Xiong, Junyuan, Rosen, Galit, Patel, Manish R.

“…Abstract only 4528 Background: Avelumab, a fully human anti‒PD-L1 IgG1 antibody, has shown promising efficacy and safety in 2 cohorts of patients (pts) with…”
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Avelumab in patients with metastatic urothelial carcinoma: Pooled results from two cohorts of the phase 1b JAVELIN Solid Tumor trial by Patel, Manish R., Ellerton, John Allan, Infante, Jeffrey R., Agrawal, Manish, Gordon, Michael S., Aljumaliy, Raid, Britten, Carolyn D., Dirix, Luc, Lee, Keun-Wook, Taylor, Matthew H., Schöffski, Patrick, Wang, Ding, Ravaud, Alain, Gelb, Arnold, Xiong, Junyuan, Rosen, Galit, Apolo, Andrea B.

“…Abstract only 330 Background: Avelumab is a fully human anti‒PD-L1 IgG1 antibody with promising efficacy and safety in patients (pts) with metastatic…”
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Sustained Virologic Response 12 Weeks Post-Treatment With ABT-450/Ritonavir/Ombitasvir and Dasabuvir With Ribavirin (SAPPHIRE I and II) is Independent of Patient Subgroups: 444 by Brunetto, Maurizia Rossana, Makara, Mihály, Hinrichsen, Holger, Hanson, John, Bennett, Michael, Lawitz, Eric, Xiong, Junyuan, Coakley, Eoin, Baykal, Tolga, Neff, Guy

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475 SAPPHIRE I: Phase 3 Placebo-Controlled Study of Interferon-Free, 12-Week Regimen of ABT-450/r/ABT-267, ABT-333, and Ribavirin in 631 Treatment-Naïve Adults With Hepatitis C Virus Genotype 1 by Kowdley, Kris V, Feld, Jordan J, Coakley, Eoin, Sigal, Samuel, Nelson, David R, Crawford, Darrell, Weiland, Ola, Aguilar, Humberto, Xiong, Junyuan, DaSilva-Tillmann, Barbara, Larsen, Lois, Podsadecki, Thomas

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235 SAPPHIRE II: Phase 3 Placebo-Controlled Study of Interferon-Free, 12-Week Regimen of ABT-450/r/ABT-267, ABT-333, and Ribavirin in 394 Treatment-Experienced Adults With Hepatitis C Virus Genotype 1 by Jacobson, Ira M, Zeuzem, Stefan, Baykal, Tolga, Marinho, Rui T, Poordad, Fred, Bourliere, Marc, Sulkowski, Mark, Wedemeyer, Heiner, Tam, Edward, Desmond, Paul V, Jensen, Donald M, Di Bisceglie, Adrian M, Varunok, Peter, Hassanein, Tarek, Xiong, Junyuan, DaSilva-Tillmann, Barbara, Larsen, Lois, Podsadecki, Thomas

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1222ABT-450/r/Ombitasvir and Dasabuvir with Ribavirin Achieves High Sustained Virologic Response Rates Regardless of Baseline Characteristics: Pooled Analyses of the SAPPHIRE-I and SAPPHIRE-II Studies by Feld, Jordan J., Weiland, Ola, Marinho, Rui Tato, Wedemeyer, Heiner, Jacobson, Ira M., Jensen, Donald M., Hassanein, Tarek, De Ledinghen, Victor, Diago, Moisés, Magenta, Lorenzo, De Knegt, Robert J., Xiong, Junyuan J., Coakley, Eoin, Baykal, Tolga, Tatsch, Fernando, Foster, Graham R.

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A Comparative Study of Academic Networks in Computer Science and Physics by Xiong, Junyuan

“…Academic networks derived from research papers, in particular citation and co-author networks, have been studied widely. Although networks in an individual…”
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