Search Results - "Xiong, Jian‐ping"

METTL1 overexpression is correlated with poor prognosis and promotes hepatocellular carcinoma via PTEN by Tian, Qiu-Hong, Zhang, Mei-Fang, Zeng, Jin-Sheng, Luo, Rong-Guang, Wen, Yang, Chen, Jun, Gan, Liu-Gen, Xiong, Jian-Ping

“…RNA methylation is emerging as an important regulator of gene expression. Dysregulation of methyltransferase that is essential for RNA modification contributes…”
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Cryo-EM structures of full-length integrin αIIbβ3 in native lipids by Adair, Brian D., Xiong, Jian-Ping, Yeager, Mark, Arnaout, M. Amin

“…Platelet integrin αIIbβ3 is maintained in a bent inactive state (low affinity to physiologic ligand), but can rapidly switch to a ligand-competent…”
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Structure-guided design of pure orthosteric inhibitors of αIIbβ3 that prevent thrombosis but preserve hemostasis by Adair, Brian D., Alonso, José L., van Agthoven, Johannes, Hayes, Vincent, Ahn, Hyun Sook, Yu, I-Shing, Lin, Shu-Wha, Xiong, Jian-Ping, Poncz, Mortimer, Arnaout, M. Amin

“…A prevailing dogma is that inhibition of vascular thrombosis by antagonizing platelet integrin αIIbβ3 cannot be achieved without compromising hemostasis, thus…”
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Structure and mechanics of integrin-based cell adhesion by Arnaout, M Amin, Goodman, Simon L, Xiong, Jian-Ping

“…Integrins are α/β heterodimeric adhesion glycoprotein receptors that regulate a wide variety of dynamic cellular processes such as cell migration,…”
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miR-320 enhances the sensitivity of human colon cancer cells to chemoradiotherapy in vitro by targeting FOXM1 by Wan, Lu-Ying, Deng, Jun, Xiang, Xiao-Jun, Zhang, Ling, Yu, Feng, Chen, Jun, Sun, Zhe, Feng, Miao, Xiong, Jian-Ping

“…•miR-320 plays a significant role in chemoresistance.•This role might be attribute to targeting FOXM1.•The Wnt/β-catenin pathway also involves in this…”
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The Spectroscopic Binaries from the LAMOST Medium-resolution Survey. I. Searching for Double-lined Spectroscopic Binaries with a Convolutional Neural Network by Zhang, Bo, Jing, Ying-Jie, Yang, Fan, Wan, Jun-Chen, Ji, Xin, Fu, Jian-Ning, Liu, Chao, Zhang, Xiao-Bin, Luo, Feng, Tian, Hao, Zhou, Yu-Tao, Wang, Jia-Xin, Guo, Yan-Jun, Zong, Weikai, Xiong, Jian-Ping, Li, Jiao

“…Abstract We developed a convolutional neural network model to distinguish the double-lined spectroscopic binaries (SB2s) from others based on single-exposure…”
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Prognostic significance of the fibrinogen-to-albumin ratio in gallbladder cancer patients by Xu, Wei-Yu, Zhang, Hao-Hai, Xiong, Jian-Ping, Yang, Xiao-Bo, Bai, Yi, Lin, Jian-Zhen, Long, Jun-Yu, Zheng, Yong-Chang, Zhao, Hai-Tao, Sang, Xin-Ting

“…To investigate the prognostic role of fibrinogen-to-albumin ratio (FAR) on patients with gallbladder cancer (GBC) in this study. One hundred and fifty-four GBC…”
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Crystal Structure of the Extracellular Segment of Integrin αVβ3 in Complex with an Arg-Gly-Asp Ligand by XIONG, Jian-Ping, STEHLE, Thilo, RONGGUANG ZHANG, JOACHIMIAK, Andrzej, FRECH, Matthias, GOODMAN, Simon L, ARNAOUT, M. Amin

“…The structural basis for the divalent cation-dependent binding of heterodimeric αβ integrins to their ligands, which contain the prototypical Arg-Gly-Asp…”
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A structural basis for lithium and substrate binding of an inositide phosphatase by Dollins, D. Eric, Xiong, Jian-Ping, Endo-Streeter, Stuart, Anderson, David E., Bansal, Vinay S., Ponder, Jay W., Ren, Yi, York, John D.

“…Inositol polyphosphate 1-phosphatase (INPP1) is a prototype member of metal-dependent/lithium-inhibited phosphomonoesterase protein family defined by a…”
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Camrelizumab in different PD-L1 expression cohorts of pre-treated advanced or metastatic non-small cell lung cancer: a phase II study by Yang, Jin-Ji, Huang, Cheng, Fan, Yun, Pan, Hongming, Feng, Jifeng, Jiang, Liyan, Li, Xing-Ya, Liu, Xiao-Qing, Xiong, Jian-Ping, Zhao, Yan-Qiu, Cheng, Ying, Ma, Rui, Wang, Jie, Wang, Yina, Liu, Yan-Hui, Lin, Dong-Mei, Wang, Tao, Shi, Wei, Zou, Jianjun, Wu, Yi-Long

“…Background This phase II study evaluated camrelizumab in different PD-L1 expression cohorts of patients with previously treated advanced/metastatic non-small…”
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Nomogram to predict overall survival after gallbladder cancer resection in China by Bai, Yi, Liu, Zhi-Song, Xiong, Jian-Ping, Xu, Wei-Yu, Lin, Jian-Zhen, Long, Jun-Yu, Miao, Fei, Huang, Han-Chun, Wan, Xue-Shuai, Zhao, Hai-Tao

“…To integrate clinically significant variables related to prognosis after curative resection for gallbladder carcinoma (GBC) into a predictive nomogram. One…”
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MiR-1271 Inhibits Cell Proliferation, Invasion and EMT in Gastric Cancer by Targeting FOXQ1 by Xiang, Xiao-Jun, Deng, Jun, Liu, Ya-Wen, Wan, Lu-Ying, Feng, Miao, Chen, Jun, Xiong, Jian-Ping

“…Background/Aims: FOXQ1 overexpression has been reported to enhance tumor growth and invasion. However, the biological function of FOXQ1 and the mechanism…”
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A New Scoring System to Predict Lymph Node Metastasis and Prognosis After Surgery for Gastric Cancer by Kang, Wen-Zhe, Xiong, Jian-Ping, Li, Yang, Jin, Peng, Xie, Yi-Bin, Xu, Quan, Zhong, Yu-Xin, Tian, Yan-Tao

“…Lymph node metastasis is one of the most important factors affecting the prognosis of gastric cancer patients. The purpose of this study is to develop a new…”
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Simultaneous MV‐kV imaging for intrafractional motion management during volumetric‐modulated arc therapy delivery by Hunt, Margie A., Sonnick, Mark, Pham, Hai, Regmi, Rajesh, Xiong, Jian‐ping, Morf, Daniel, Mageras, Gig S., Zelefsky, Michael, Zhang, Pengpeng

“…The purpose of this study was to evaluate the accuracy and clinical feasibility of a motion monitoring method employing simultaneously acquired MV and kV…”
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Kilovoltage Imaging of Implanted Fiducials to Monitor Intrafraction Motion With Abdominal Compression During Stereotactic Body Radiation Therapy for Gastrointestinal Tumors by Yorke, Ellen, PhD, Xiong, Ying, MD, Han, Qian, MD, Zhang, Pengpeng, PhD, Mageras, Gikas, PhD, Lovelock, Michael, PhD, Pham, Hai, PhD, Xiong, Jian-Ping, MS, Goodman, Karyn A., MD, MS

“…Purpose To assess intrafraction respiratory motion using a commercial kilovoltage imaging system for abdominal tumor patients with implanted fiducials and…”
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Can Gastric Cancer Patients with High Mandard Score Benefit from Neoadjuvant Chemotherapy? by Kang, Wen-Zhe, Wang, Bing-Zhi, Li, Deng-Feng, Jiang, Zhi-Chao, Xiong, Jian-Ping, Li, Yang, Jin, Peng, Shao, Xin-Xin, Hu, Hai-Tao, Tian, Yan-Tao

“…A high Mandard score may indicate the tumor is insensitive to chemotherapy. We analyzed tumor regression and lymph node response under different Mandard scores…”
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Seepage and Dynamic Characteristics of Carbonaceous Mudstone Coarse-Grained Soil Embankment with Different Gradations by He, Zhong-ming, Liu, Xiao-qu, Huang, Ke, Xiong, Jian-ping

“…This study investigates the seepage and deformation characteristics of carbonaceous mudstone coarse-grained soil embankment with different gradations under the…”
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Efficacy and safety of recombinant human lymphotoxin‐α derivative with cisplatin and fluorouracil in patients with metastatic esophageal squamous cell carcinoma: A randomized, multicenter, open‐label, controlled, phase 2b trial by Wang, Feng‐hua, Wang, Yun, Sun, Guo‐ping, Chen, Jian‐hua, Lin, Ying‐cheng, Liu, Wei, Zheng, Rong‐sheng, Chen, Jia, Zhang, He‐long, Lan, Hai‐tao, Qi, Jun, Liu, Yang‐qing, Deng, Yan‐ming, Zhao, Heng, Xiong, Jian‐ping, Xu, Qing, Jiang, Wen‐qi, Li, Yu‐hong

“…BACKGROUND Recombinant human lymphotoxin‐α derivative (rhLTα‐Da) is a lymphotoxin‐α derivative that is missing 27 N‐terminal amino acid residues. Previous…”
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Lichenoid drug eruption caused by imatinib mesylate in a Chinese patient with gastrointestinal stromal tumor by Luo, Jing-Ru, Xiang, Xiao-Jun, Xiong, Jian-Ping

“…Imatinib mesylate, the first agent approved for the treatment of unresectable or metastatic gastrointestinal stromal tumor, is a tyrosine kinase inhibitor…”
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Famitinib versus placebo in the treatment of refractory metastatic colorectal cancer: a multicenter, randomized, double-blinded, placebo-controlled, phase II clinical trial by Xu, Rui-Hua, Shen, Lin, Wang, Ke-Ming, Wu, Gang, Shi, Chun-Mei, Ding, Ke-Feng, Lin, Li-Zhu, Wang, Jin-Wan, Xiong, Jian-Ping, Wu, Chang-Ping, Li, Jin, Liu, Yun-Peng, Wang, Dong, Ba, Yi, Feng, Jue-Ping, Bai, Yu-Xian, Bi, Jing-Wang, Ma, Li-Wen, Lei, Jian, Yang, Qing, Yu, Hao

“…Metastatic colorectal cancer (mCRC) patients with progressive disease after all available standard therapies need new medication for further treatment…”
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