Search Results - "Xiong, Chiyi"
-
1
Effective Photothermal Chemotherapy Using Doxorubicin-Loaded Gold Nanospheres That Target EphB4 Receptors in Tumors
Published in Cancer research (Chicago, Ill.) (15-09-2012)“…Photothermal ablation (PTA) is an emerging technique that uses near-infrared (NIR) laser light-generated heat to destroy tumor cells. However, complete tumor…”
Get full text
Journal Article -
2
Targeted Photothermal Ablation of Murine Melanomas with Melanocyte-Stimulating Hormone Analog–Conjugated Hollow Gold Nanospheres
Published in Clinical cancer research (01-02-2009)“…Purpose: To develop melanoma-targeted hollow gold nanospheres (HAuNS) and evaluate their potential utility for selective photothermal ablation in melanoma…”
Get full text
Journal Article -
3
Effects of Photoacoustic Imaging and Photothermal Ablation Therapy Mediated by Targeted Hollow Gold Nanospheres in an Orthotopic Mouse Xenograft Model of Glioma
Published in Cancer research (Chicago, Ill.) (01-10-2011)“…Advancements in nanotechnology have made it possible to create multifunctional nanostructures that can be used simultaneously to image and treat cancers. For…”
Get full text
Journal Article -
4
Peptide-conjugated polymeric micellar nanoparticles for Dual SPECT and optical imaging of EphB4 receptors in prostate cancer xenografts
Published in Biomaterials (01-09-2011)“…Abstract EphB4, a member of the largest family of receptor tyrosine kinases, is overexpressed in numerous tumors. In this study, we developed a new class of…”
Get full text
Journal Article -
5
Receptor-mediated transcytosis: A mechanism for active extravascular transport of nanoparticles in solid tumors
Published in Journal of controlled release (10-08-2012)“…Targeted nanoparticle-based delivery systems have been used extensively to develop effective cancer theranostics. However, how targeting ligands affect…”
Get full text
Journal Article -
6
Targeting Forward and Reverse EphB4/EFNB2 Signaling by a Peptide with Dual Functions
Published in Scientific reports (16-01-2020)“…The tyrosine kinase receptor EphB4 is frequently overexpressed in ovarian and other solid tumors and is involved in interactions between tumor cells and the…”
Get full text
Journal Article -
7
Cisplatin-loaded hollow gold nanoparticles for laser-triggered release
Published in Cancer nanotechnology (2018)“…Background Hollow gold nanoparticles (HGNPs) exposed to near-infrared (NIR) light yield photothermal effects that can trigger a variety of biological effects…”
Get full text
Journal Article -
8
Concurrent Injection of Unlabeled Antibodies Allows Positron Emission Tomography Imaging of Programmed Cell Death Ligand 1 Expression in an Orthotopic Pancreatic Tumor Model
Published in ACS omega (21-04-2020)“…Purpose: Among the treatment options for pancreatic ductal adenocarcinoma (PDAC) are antibodies against the programmed cell death receptor 1 (PD-1)/programmed…”
Get full text
Journal Article -
9
Structure−Affinity Relationships of Glutamine Mimics Incorporated into Phosphopeptides Targeted to the SH2 Domain of Signal Transducer and Activator of Transcription 3
Published in Journal of medicinal chemistry (08-10-2009)“…In cancer cells, signal transducer and activator of transcription 3 (Stat3) participates in aberrant growth, survival, angiogenesis, and invasion signals and…”
Get full text
Journal Article -
10
Conformationally Constrained Peptidomimetic Inhibitors of Signal Transducer and Activator of Transcription 3: Evaluation and Molecular Modeling
Published in Journal of medicinal chemistry (23-04-2009)“…Signal transducer and activator of transcription 3 (Stat3) is involved in aberrant growth and survival signals in malignant tumor cells and is a validated…”
Get full text
Journal Article -
11
Development of a Targeted Gene Vector Platform Based on Simian Adenovirus Serotype 24
Published in Journal of Virology (01-10-2010)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
12
Targeting Phosphatidylserine on Apoptotic Cells with Phages and Peptides Selected from a Bacteriophage Display Library
Published in Molecular imaging (01-11-2007)“…Phosphatidylserine (PS) is a well-characterized biomarker for apoptosis. Ligands that bind to PS can be used for noninvasive imaging of therapy-induced cell…”
Get full text
Journal Article -
13
Regioselective and Stereoselective Nucleophilic Ring Opening Reactions of A Phenyl-Substituted Aziridine: Enantioselective Synthesis of β-Substituted Tryptophan, Cysteine, and Serine Derivatives
Published in Journal of organic chemistry (22-02-2002)“…The asymmetric synthesis of β-phenyl-substituted cysteine, tryptophan, and serine derivatives was successfully developed. In this approach, the key…”
Get full text
Journal Article -
14
Iodine scanning of a phenazine inhibitor of vacuolar sorting
Published in Bioorganic & medicinal chemistry letters (01-03-2010)“…The synthesis and biological activity of N-phenylphenazin-2-amine and 4 iodinated derivatives is reported. Affinity reagents are often used to address the…”
Get full text
Journal Article -
15
A General Asymmetric Synthesis of syn- and anti-β-Substituted Cysteine and Serine Derivatives
Published in Journal of organic chemistry (17-05-2002)“…A stereodivergent synthetic route has been developed to make the optically pure anti- and syn-β-substituted cysteine and serine derivatives. In this approach,…”
Get full text
Journal Article -
16
Stereoselective Synthesis of Dipeptide β-Turn Mimetics: 7-Benzyl and 8-Phenyl Substituted Azabicyclo[4.3.0]nonane Amino Acid Esters
Published in Journal of organic chemistry (06-09-2002)“…A stereoselective method has been developed for the synthesis of 7- and 8-substituted dipeptide β-turn mimetic azabicyclo[4.3.0]nonane amino acid esters. The…”
Get full text
Journal Article -
17
99mTc/Re tricarbonyl biguanide complexes for cancer theranostics
Published in Nuclear medicine and biology (01-05-2022)Get full text
Journal Article -
18
P-012 - 99mTc/Re tricarbonyl biguanide complexes for cancer theranostics
Published in Nuclear medicine and biology (01-05-2022)Get full text
Journal Article -
19
Copper-64 Labeled PEGylated Exosomes for In Vivo Positron Emission Tomography and Enhanced Tumor Retention
Published in Bioconjugate chemistry (16-10-2019)“…Exosomes have attracted tremendous attention due to their important role in physiology, pathology, and oncology, as well as promising potential in biomedical…”
Get full text
Journal Article -
20
Integrin αvβ3-Targeted [64Cu]CuS Nanoparticles for PET/CT Imaging and Photothermal Ablation Therapy
Published in Bioconjugate chemistry (19-12-2018)“…Copper sulfide (CuS) nanoparticles have been considered one of the most clinical relevant nanosystems because of their straightforward chemistry, small…”
Get full text
Journal Article