Search Results - "Xing SHEN"
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ClipKIT: A multiple sequence alignment trimming software for accurate phylogenomic inference
Published in PLoS biology (02-12-2020)“…Highly divergent sites in multiple sequence alignments (MSAs), which can stem from erroneous inference of homology and saturation of substitutions, are thought…”
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Contentious relationships in phylogenomic studies can be driven by a handful of genes
Published in Nature ecology & evolution (10-04-2017)“…Phylogenomic studies have resolved countless branches of the tree of life, but remain strongly contradictory on certain, contentious relationships. Here, we…”
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Rooting the Animal Tree of Life
Published in Molecular biology and evolution (01-10-2021)“…Abstract Identifying our most distant animal relatives has emerged as one of the most challenging problems in phylogenetics. This debate has major implications…”
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PhyKIT: a broadly applicable UNIX shell toolkit for processing and analyzing phylogenomic data
Published in Bioinformatics (Oxford, England) (25-08-2021)“…Abstract Motivation Diverse disciplines in biology process and analyze multiple sequence alignments (MSAs) and phylogenetic trees to evaluate their information…”
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Evaluating Fast Maximum Likelihood-Based Phylogenetic Programs Using Empirical Phylogenomic Data Sets
Published in Molecular biology and evolution (01-02-2018)“…The sizes of the data matrices assembled to resolve branches of the tree of life have increased dramatically, motivating the development of programs for fast,…”
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A General Approach to Design Dual Ratiometric Fluorescent and Photoacoustic Probes for Quantitatively Visualizing Tumor Hypoxia Levels In Vivo
Published in Angewandte Chemie International Edition (07-02-2022)“…Herein, we describe an energy balance strategy between fluorescence and photoacoustic effects by sulfur substitution to transform existing hemicyanine dyes…”
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Recent Advances in Carbon Nanomaterials for Cancer Phototherapy
Published in Chemistry : a European journal (15-03-2019)“…Carbon nanomaterials have received great attention from the scientific community over the past few decades because of their unique physical and chemical…”
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Extensive loss of cell-cycle and DNA repair genes in an ancient lineage of bipolar budding yeasts
Published in PLoS biology (21-05-2019)“…Cell-cycle checkpoints and DNA repair processes protect organisms from potentially lethal mutational damage. Compared to other budding yeasts in the subphylum…”
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The development of three long universal nuclear protein-coding locus markers and their application to osteichthyan phylogenetics with nested PCR
Published in PloS one (14-06-2012)“…Universal nuclear protein-coding locus (NPCL) markers that are applicable across diverse taxa and show good phylogenetic discrimination have broad applications…”
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An investigation of irreproducibility in maximum likelihood phylogenetic inference
Published in Nature communications (30-11-2020)“…Phylogenetic trees are essential for studying biology, but their reproducibility under identical parameter settings remains unexplored. Here, we find that 3515…”
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OrthoSNAP: A tree splitting and pruning algorithm for retrieving single-copy orthologs from gene family trees
Published in PLoS biology (13-10-2022)“…Molecular evolution studies, such as phylogenomic studies and genome-wide surveys of selection, often rely on gene families of single-copy orthologs (SC-OGs)…”
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Exosomes Derived from Mesenchymal Stem Cells Rescue Myocardial Ischaemia/Reperfusion Injury by Inducing Cardiomyocyte Autophagy Via AMPK and Akt Pathways
Published in Cellular physiology and biochemistry (01-01-2017)“…Background/Aims: Reperfusion after an ischaemic insult might cause infarct extension. Mesenchymal stem cell (MSC)-derived exosomes could attenuate myocardial…”
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Tempo and Mode of Genome Evolution in the Budding Yeast Subphylum
Published in Cell (29-11-2018)“…Budding yeasts (subphylum Saccharomycotina) are found in every biome and are as genetically diverse as plants or animals. To understand budding…”
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PhyloFisher: A phylogenomic package for resolving eukaryotic relationships
Published in PLoS biology (06-08-2021)“…Phylogenomic analyses of hundreds of protein-coding genes aimed at resolving phylogenetic relationships is now a common practice. However, no software…”
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HGT is widespread in insects and contributes to male courtship in lepidopterans
Published in Cell (04-08-2022)“…Horizontal gene transfer (HGT) is an important evolutionary force shaping prokaryotic and eukaryotic genomes. HGT-acquired genes have been sporadically…”
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Evolutionary instability of CUG-Leu in the genetic code of budding yeasts
Published in Nature communications (14-05-2018)“…The genetic code used in nuclear genes is almost universal, but here we report that it changed three times in parallel during the evolution of budding yeasts…”
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Surface‐Enhanced Raman Probes Based on Gold Nanomaterials for in vivo Diagnosis and Imaging
Published in Chemistry, an Asian journal (01-04-2022)“…Surface‐enhanced Raman scattering (SERS) has received considerable attention from researchers due to its high molecular specificity, high sensitivity,…”
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Reconstructing the Backbone of the Saccharomycotina Yeast Phylogeny Using Genome-Scale Data
Published in G3 : genes - genomes - genetics (01-12-2016)“…Understanding the phylogenetic relationships among the yeasts of the subphylum Saccharomycotina is a prerequisite for understanding the evolution of their…”
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Recent progress in metal complexes functionalized nanomaterials for photodynamic therapy
Published in Chemical communications (Cambridge, England) (06-06-2023)“…Metal complexes have shown promise as photosensitizers for cancer diagnosis and therapeutics. However, the vast majority of metal photosensitizers are not…”
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Near-infrared-II-activatable sulfur-deficient plasmonic Bi2S3-x-Au heterostructures for photoacoustic imaging-guided ultrasound enhanced high performance phototherapy
Published in Journal of colloid and interface science (15-08-2023)“…An “all-in-one” phototheranostic nanoplatform based on a single NIR-II light-responsive Schottky-type Bi2S3-x-Au heterostructure for photoacoustic…”
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