Search Results - "Xing, Zikang"
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A new agricultural drought index considering the irrigation water demand and water supply availability
Published in Natural hazards (Dordrecht) (01-12-2020)“…Agricultural drought has a tremendous impact on crop yields and economic development under the context of global climate change. As an essential component of…”
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2
IDO1 can impair NK cells function against non-small cell lung cancer by downregulation of NKG2D Ligand via ADAM10
Published in Pharmacological research (01-03-2022)“…Indoleamine 2,3-dioxygenase 1 (IDO1) catalyzes the rate-limiting step in tryptophan catabolism along the kynurenine (Kyn) pathway and exerts immunosuppressive…”
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3
IDO1/TDO dual inhibitor RY103 targets Kyn-AhR pathway and exhibits preclinical efficacy on pancreatic cancer
Published in Cancer letters (01-12-2021)“…Indoleamine 2,3-dioxygenase 1 (IDO1) catalyzing the conversion of tryptophan (Trp) to kynurenine (Kyn) in kynurenine pathway (KP) is involved in the…”
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What is the prospect of indoleamine 2,3-dioxygenase 1 inhibition in cancer? Extrapolation from the past
Published in Journal of experimental & clinical cancer research (08-02-2021)“…Indoleamine 2,3-dioxygenase 1 (IDO1), a monomeric heme-containing enzyme, catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan…”
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5
Both IDO1 and TDO contribute to the malignancy of gliomas via the Kyn–AhR–AQP4 signaling pathway
Published in Signal transduction and targeted therapy (21-02-2020)“…Indoleamine 2,3-dioxygenase 1 (IDO1), indoleamine 2,3-dioxygenase 2 (IDO2), and tryptophan 2,3-dioxygenase (TDO) initiate the first step of the kynurenine…”
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IDO1 Inhibitor RY103 Suppresses Trp-GCN2-Mediated Angiogenesis and Counters Immunosuppression in Glioblastoma
Published in Pharmaceutics (28-06-2024)“…Glioma is characterized by strong immunosuppression and excessive angiogenesis. Based on existing reports, it can be speculated that the resistance to…”
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H2S suppresses indoleamine 2, 3-dioxygenase 1 and exhibits immunotherapeutic efficacy in murine hepatocellular carcinoma
Published in Journal of experimental & clinical cancer research (18-02-2019)“…Background Over-expression and over-activation of immunosuppressive enzyme indoleamine 2, 3 -dioxygenase 1 (IDO1) is a key mechanism of cancer immune escape…”
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8
A spatio-temporal dam deformation zoning method considering non-uniform distribution of monitoring information
Published in IEEE access (01-01-2021)“…Deformation is the most intuitive indicator of the actual working status of a concrete dam. Zoning the variation regulation of dam deformation is one of the…”
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Correction: Both IDO1 and TDO contribute to the malignancy of gliomas via the Kyn–AhR–AQP4 signaling pathway
Published in Signal transduction and targeted therapy (08-11-2021)Get full text
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Tryptophan deficiency induced by indoleamine 2,3‐dioxygenase 1 results in glucose transporter 1‐dependent promotion of aerobic glycolysis in pancreatic cancer
Published in MedComm (2020) (01-05-2024)“…Indoleamine 2,3‐dioxygenase 1 (IDO1), the key enzyme in the catabolism of the essential amino acid tryptophan (Trp) through kynurenine pathway, induces immune…”
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Amyloid β neurotoxicity is IDO1–Kyn–AhR dependent and blocked by IDO1 inhibitor
Published in Signal transduction and targeted therapy (12-06-2020)Get full text
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12
Forty‐three key gene expressions involved in the effect of indoleamine 2,3‐dioxygenase 1 expression on cancer prognosis may be a potential indoleamine 2,3‐dioxygenase 1 inhibitor biomarker
Published in Clinical and translational medicine (01-02-2021)“…SEE PDF] Specifically, we used Kaplan-Meier method and Cox proportional hazards (CoxPH) regression model to compare the overall survival (OS) and…”
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13
Altered drought propagation under the influence of reservoir regulation
Published in Journal of hydrology (Amsterdam) (01-12-2021)“…•A diagnosis frame was proposed to assess the reservoir impacts on drought propagation.•Strong aggravating effect of reservoir on drought propagations was…”
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Lagged influence of ENSO regimes on droughts over the Poyang Lake basin, China
Published in Atmospheric research (01-09-2022)“…The regional drought predictability is strongly influenced by teleconnections factors. Among them, El Niño-Southern Oscillation (ENSO) is important to drought…”
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Disentangling the spatially combined and temporally lagged influences of climate oscillations on seasonal droughts in the East Asian monsoon influenced Poyang Lake Basin
Published in Atmospheric research (01-11-2024)“…Large-scale climate oscillations are the main forcings affecting regional meteorological droughts and being relevant to sources of their predictability…”
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Both IDO1 and TDO contribute to the malignancy of gliomas via the Kyn-AhR-AQP4 signaling pathway
Published in Signal transduction and targeted therapy (21-02-2020)“…Indoleamine 2,3-dioxygenase 1 (IDO1), indoleamine 2,3-dioxygenase 2 (IDO2), and tryptophan 2,3-dioxygenase (TDO) initiate the first step of the kynurenine…”
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17
Optimization and analysis of a grounded type dynamic vibration absorber with lever component
Published in Science progress (1916) (01-10-2020)“…Dynamic vibration absorber (DVA) with large auxiliary mass has better control performance, but it is also more bulky. Therefore, the mass ratio (the ratio of…”
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Evaluation and comparison of the commonly used bioassays of human indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO)
Published in Bioorganic chemistry (01-11-2020)“…[Display omitted] •Reaction time has limited effect on NFK assay and Kyn adduct assay of IDO1/TDO.•The IC50 values obtained from NFK assay are higher than that…”
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A review of the adaptability of hydrological models for drought forecasting
Published in Proceedings of the International Association of Hydrological Sciences (16-09-2020)“…Drought intensity and frequency are increasing in recent years in multiple regions across the world due to global climate change and consequently drought…”
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Wide Solid Angle Scanning Conical Conformal Phased Array Antenna Based on Bidirectional Beam
Published in 2024 IEEE 7th International Conference on Electronic Information and Communication Technology (ICEICT) (31-07-2024)“…This paper presents a conical conformal antenna array with wide solid angle scanning range. The proposed antenna array employs two columns of conformal patch…”
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