Search Results - "Xing, Yanjiang"

Gefitinib and fostamatinib target EGFR and SYK to attenuate silicosis: a multi-omics study with drug exploration by Wang, Mingyao, Zhang, Zhe, Liu, Jiangfeng, Song, Meiyue, Zhang, Tiantian, Chen, Yiling, Hu, Huiyuan, Yang, Peiran, Li, Bolun, Song, Xiaomin, Pang, Junling, Xing, Yanjiang, Cao, Zhujie, Guo, Wenjun, Yang, Hao, Wang, Jing, Yang, Juntao, Wang, Chen

“…Silicosis is the most prevalent and fatal occupational disease with no effective therapeutics, and currently used drugs cannot reverse the disease progress…”
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Autoimmunity in Pulmonary Arterial Hypertension: Evidence for Local Immunoglobulin Production by Shu, Ting, Xing, Yanjiang, Wang, Jing

“…Pulmonary arterial hypertension (PAH) is a progressive life-threatening disease. The notion that autoimmunity is associated with PAH is widely recognized by…”
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A novel piperidine identified by stem cell-based screening attenuates pulmonary arterial hypertension by regulating BMP2 and PTGS2 levels by Xing, Yanjiang, Zhao, Shuang, Wei, Qingxia, Gong, Shiqiang, Zhao, Xin, Zhou, Fang, Ai-Lamki, Rafia, Ortmann, Daniel, Du, Mingxia, Pedersen, Roger, Shang, Guangdong, Si, Shuyi, Morrell, Nicholas W, Yang, Jun

“…Genetic defects in bone morphogenetic protein type II receptor (BMPRII) signalling and inflammation contribute to the pathogenesis of pulmonary arterial…”
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Enhancement of phagocytosis and cytotoxicity in macrophages by tumor-derived IL-18 stimulation by Henan, Xu, Toyota, Naoka, Yanjiang, Xing, Fujita, Yuuki, Zhijun, Huang, Touma, Maki, Qiong, Wu, Sugimoto, Kenkichi

“…Inoculation of mice with the murine NFSA cell line caused the formation of large tumors with necrotic tumor cores. FACS analysis revealed accumulations of…”
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Endothelial phosphodiesterase 4B inactivation ameliorates endothelial-to-mesenchymal transition and pulmonary hypertension by Xing, Yanjiang, Hou, Yangfeng, Fan, Tianfei, Gao, Ran, Feng, Xiaohang, Li, Bolun, Pang, Junling, Guo, Wenjun, Shu, Ting, Li, Jinqiu, Yang, Jie, Mao, Qilong, Luo, Ya, Qi, Xianmei, Yang, Peiran, Liang, Chaoyang, Zhao, Hongmei, Chen, Wenhui, Wang, Jing, Wang, Chen

“…Pulmonary hypertension (PH) is a fatal disorder characterized by pulmonary vascular remodeling and obstruction. The phosphodiesterase 4 (PDE4) family…”
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miR-370 is stage-specifically expressed during mouse embryonic development and regulates Dnmt3a by Qi, Liu, Hongjuan, He, Ning, Gu, Zhengbin, Han, Yanjiang, Xing, Tiebo, Zeng, Zhijun, Huang, Qiong, Wu

“…► We analyse the spatiotemporal expression pattern of miR-370. ► miR-370 is a stage- and tissue-specific miRNA in implantation embryos. ► Dnmt3a is shown to be…”
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Evidence of Accumulated Endothelial Progenitor Cells in the Lungs of Rats with Pulmonary Arterial Hypertension by 89Zr-oxine PET Imaging by Liu, Yimin, Zhao, Xin, Ding, Jie, Xing, Yanjiang, Zhou, Meijun, Wang, Xuezhu, Zhu, Wenjia, Huo, Li, Yang, Jun

“…Endothelial progenitor cells (EPCs) play a major role in regulating pulmonary vascular remodeling during pulmonary arterial hypertension (PAH) development…”
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Role of FGF10 on tumorigenesis by MS‐K by Sugimoto, Kenkichi, Yoshida, Suzuka, Mashio, Yuka, Toyota, Naoka, Xing, Yanjiang, Xu, Henan, Fujita, Yuki, Huang, Zhijun, Touma, Maki, Wu, Qiong

“…Murine MS‐K and NFSA cell lines formed tumor after inoculation into mouse and both cell lines expressed high level of vascular endothelial growth factor‐A…”
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Expression of non-coding RNA AB063319 derived from Rian gene during mouse development by Gu, Tiantian, He, Hongjuan, Xing, Yanjiang, Liu, Qi, Gu, Ning, Kenkichi, Sugimoto, Jiang, Huijie, Wu, Qiong

“…The regulatory functions of many non-coding RNAs (ncRNAs) were widely recognized. However, there are very few publications on long intronic ncRNAs. The…”
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Expression Patterns of Ubiquitin Conjugating Enzyme UbcM2 During Mouse Embryonic Development by YANJIANG, XING, HONGJUAN, HE, TIANTIAN, GU, YAN, ZHANG, ZHIJUN, HUANG, QIONG, WU

“…Ubiquitin conjugating enzyme UbcM2 (Ubiquitin-conjugating enzymes from Mice, the number reveals the identification order) has been implicated in many critical…”
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Expression patterns of imprinted gene Inpp5f-v3 during mouse brain development by Yan, Chen, Hongjuan, He, Yanjiang, Xing, Zhengbin, Han, Kai, Li, Fengwei, Zhang, Jing, Hou, Qiong, Wu

“…Inpp5f - v3 is a transcriptional variant of Inpp5f (inositol polyphosphate-5-phosphatase F) and locates in distal mouse chromosome 7. It is a paternally…”
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Enhancement of phagocytosis and cytotoxicity in macrophages by tumor-derived IL-18 stimulation? by Xu, Henan, Toyota, Naoka, Xing, Yanjiang, Fujita, Yuuki, Huang, Zhijun, Touma, Maki, Wu, Qiong, Sugimoto, Kenkichi

“…Inoculation of mice with the murine NFSA cell line caused theformation of large tumors with necrotic tumor cores. FACSanalysis revealed accumulations of CD11b+…”
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Eosinophils protect against pulmonary hypertension through 14-HDHA and 17-HDHA by Shu, Ting, Zhang, Jiawei, Zhou, Yitian, Chen, Zhihua, Li, Jinqiu, Tang, Qihao, Lei, Wenqi, Xing, Yanjiang, Wang, Jing, Wang, Chen

“…Pulmonary hypertension (PH) is a life-threatening disease featuring pulmonary vessel remodelling and perivascular inflammation. The effect, if any, of…”
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Abstract 14566: The Role of Eosinophils in Pulmonary Hypertension by Shu, Ting, Zhang, Jiawei, Chen, Zhihua, Zhou, Yitian, Xing, Yanjiang, Wang, Jing, Wang, Chen

“…IntroductionPulmonary hypertension (PH) is a severe life-threatening disease with insidious onset and high mortality, featured by pulmonary vascular remodeling…”
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The LPS induced pyroptosis exacerbates BMPR2 signaling deficiency to potentiate SLE‐PAH by Xing, Yanjiang, Zhao, Jiuliang, Zhou, Meijun, Jing, Shuliang, Zhao, Xin, Mao, Pei, Qian, Junyan, Huang, Can, Tian, Zhuang, Wang, Qian, Zeng, Xiaofeng, Li, Mengtao, Yang, Jun

“…Pulmonary arterial hypertension (PAH) is a common and fatal complication of systemic lupus erythematosus (SLE). Whether the BMP receptor deficiency found in…”
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Abstract 13237: Single Cell Transcriptomes Reveal Novel Macrophage and Endothelial Subtypes in Pulmonary Hypertension by Li, Bolun, Xing, Yanjiang, Zhou, Yitian, Xiao, Xingqi, Shu, Ting, Song, Xiaomin, Zhao, Hongmei, Pang, Junling, Yang, Peiran, Yu, Paul B, Wang, Jing, Wang, Chen

“…IntroductionAnimal models are widely used to study pulmonary hypertension and test experimental therapies. The detailed cellular phenotypes of these diverse…”
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Proteome, Lysine Acetylome, and Succinylome Identify Posttranslational Modification of STAT1 as a Novel Drug Target in Silicosis by Zhang, Tiantian, Wang, Yiyang, Sun, Youliang, Song, Meiyue, Pang, Junling, Wang, Mingyao, Zhang, Zhe, Yang, Peiran, Chen, Yiling, Qi, Xianmei, Zhou, Huan, Han, Zhenzong, Xing, Yanjiang, Liu, Ying, Li, Baicun, Liu, Jiangfeng, Yang, Juntao, Wang, Jing

“…Inhalation of crystalline silica dust induces incurable lung damage, silicosis, and pulmonary fibrosis. However, the mechanisms of the lung injury remain…”
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Accumulation of endothelial progenitor cells in the lung of pulmonary arterial hypertension: 89Zr-oxine cell trafficking with PET imaging in a rat model by Liu, Yimin, Zhao, Xin, Ding, Jie, Xing, Yanjiang, Wang, Xuezhu, Huo, Li, Yang, Jun

“…Background: Accumulating evidence indicates endothelial progenitor cells (EPCs) play a major role in regulating pulmonary vascular remodeling during pulmonary…”
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Inactivation of Malic Enzyme 1 in Endothelial Cells Alleviates Pulmonary Hypertension by Luo, Ya, Qi, Xianmei, Zhang, Zhenxi, Zhang, Jiawei, Li, Bolun, Shu, Ting, Li, Xiaona, Hu, Huiyuan, Li, Jinqiu, Tang, Qihao, Zhou, Yitian, Wang, Mingyao, Fan, Tianfei, Guo, Wenjun, Liu, Ying, Zhang, Jin, Pang, Junling, Yang, Peiran, Gao, Ran, Chen, Wenhui, Yan, Chen, Xing, Yanjiang, Du, Wenjing, Wang, Jing, Wang, Chen

“…Pulmonary hypertension (PH) is a progressive cardiopulmonary disease with a high mortality rate. Although growing evidence has revealed the importance of…”
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Tourism activities significantly contributed toatmospheric pollutants in a remote town of Tianshan revealed by the continuous observation of two years by Zhong, Xiaoling, Chen, Pengfei, Kang, Shichang, Zheng, Huijun, Guo, Junming, Hu, Zhaofu, Wu, Xiaobo, Li, Xiaobin, Xing, Yanjiang, Li, Chaoliu

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