Search Results - "Xing, Xupeng"
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H3K9 demethylase KDM4E is an epigenetic regulator for bovine embryonic development and a defective factor for nuclear reprogramming
Published in Development (Cambridge) (15-02-2018)“…Aberrant epigenetic reprogramming often results in developmental defects in somatic cell nuclear transfer (SCNT) embryos during embryonic genome activation…”
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2
Lead exposure activates the Nrf2/Keap1 pathway, aggravates oxidative stress, and induces reproductive damage in female mice
Published in Ecotoxicology and environmental safety (01-01-2021)“…Lead, a common metallic contaminant, is widespread in the living environment, and has deleterious effects on the reproductive systems of humans and animals…”
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3
Genome-wide analysis of DNA methylation in bovine placentas
Published in BMC genomics (08-01-2014)“…DNA methylation is an important epigenetic modification that is essential for epigenetic gene regulation in development and disease. To date, the genome-wide…”
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4
Fisetin Delays Postovulatory Oocyte Aging by Regulating Oxidative Stress and Mitochondrial Function through Sirt1 Pathway
Published in Molecules (Basel, Switzerland) (20-07-2023)“…The quality of oocytes determines the development potential of an embryo and is dependent on their timely fertilization after ovulation. Postovulatory oocyte…”
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5
CARM1 is heterogeneous in mouse four-cell embryo and important to blastocyst development
Published in Reproduction (Cambridge, England) (01-01-2020)“…Coactivator-associated arginine methyltransferase 1 (CARM1) is a type I arginine methyltransferase that methylates the arginine residues of histone and…”
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Supplementation of SkQ1 Increases Mouse In Vitro Oocyte Maturation and Subsequent Embryonic Development by Reducing Oxidative Stress
Published in Pharmaceuticals (Basel, Switzerland) (02-04-2024)“…In vitro oocyte maturation (IVM) technology is important for assisted animal and human reproduction. However, the maturation rates and developmental potential…”
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7
Modification of alternative splicing in bovine somatic cell nuclear transfer embryos using engineered CRISPR-Cas13d
Published in Science China. Life sciences (01-11-2022)“…Animal cloning can be achieved by somatic cell nuclear transfer (SCNT), but the resulting live birth rate is relatively low. We previously improved the…”
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Luteolin regulates the distribution and function of organelles by controlling SIRT1 activity during postovulatory oocyte aging
Published in Frontiers in nutrition (Lausanne) (31-07-2023)“…The quality of oocytes determines their development competence, which will be rapidly lost if the oocytes are not fertilized at the proper time after…”
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Interleukin‐32ε induces caspase‐independent apoptosis mediated by N‐Myc interactor in macrophages infected with Mycobacterium tuberculosis
Published in The FEBS journal (01-02-2019)“…Mycobacterium tuberculosis (Mtb) is the pathogen responsible for tuberculosis, a leading cause of illness and death worldwide. Growing evidence suggests that…”
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10
Fisetin Delays Postovulatory Oocyte Aging by Regulating Oxidative Stress and Mitochondrial Function through ISirt1/I Pathway
Published in Molecules (Basel, Switzerland) (01-07-2023)“…The quality of oocytes determines the development potential of an embryo and is dependent on their timely fertilization after ovulation. Postovulatory oocyte…”
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11
Melatonin significantly improves the developmental competence of bovine somatic cell nuclear transfer embryos
Published in Journal of pineal research (01-11-2015)“…Somatic cell nuclear transfer (SCNT) is a promising technology, but its application is hampered by its low efficiency. Hence, the majority of SCNT embryos fail…”
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12
SIRT1 reduces epigenetic and non-epigenetic changes to maintain the quality of postovulatory aged oocytes in mice
Published in Experimental cell research (15-02-2021)“…Postovulatory oocyte aging has a major influence on the development potential of embryos. Many antioxidants can delay oocyte aging by regulating the expression…”
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13
Methionine adenosyltransferase 2A regulates mouse zygotic genome activation and morula to blastocyst transition
Published in Biology of reproduction (01-03-2019)“…Methionine adenosyltransferase II (MAT2A) is essential to the synthesis of S-adenosylmethionine, a major methyl donor, from L-methionine and ATP. Upon…”
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14
CHAF1b, chromatin assembly factor-1 subunit b, is essential for mouse preimplantation embryos
Published in International journal of biological macromolecules (15-01-2022)“…Chromatin assembly factor-1, subunit b (CHAF1b), the p60 subunit of the chromatin-assembly factor-1 (CAF-1) complex, is an evolutionarily conserved protein…”
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Effect of ACY-1215 on cytoskeletal remodeling and histone acetylation in bovine somatic cell nuclear transfer embryos
Published in Theriogenology (15-04-2022)“…The latest studies indicated that in addition to alterations in abnormal chromosome epigenetic modifications, the abnormal cytoskeletal changes are also an…”
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Functions of intrinsic disorder in proteins involved in DNA demethylation during pre-implantation embryonic development
Published in International journal of biological macromolecules (01-09-2019)“…DNA demethylation is involved in many biological processes during pre-implantation embryonic development in mammals. To date, the complicated mechanism of DNA…”
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Deep sequencing analysis of microRNAs in bovine sperm
Published in Molecular reproduction and development (01-11-2014)“…SUMMARY microRNAs (miRNAs) are small non‐coding RNAs that participates in the regulation of many physiological pathways, but a role for spermatozoon‐delivered…”
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18
MicroRNA-34c expression in donor cells influences the early development of somatic cell nuclear transfer bovine embryos
Published in Cellular reprogramming (01-12-2014)“…The essence of the reprogramming activity of somatic cell nuclear transfer (SCNT) embryos is to produce normal fertilized embryos. However, reprogramming of…”
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19
Application of adaptive genetic algorithm in robot path planning
Published in Xi'an Gongcheng Daxue xuebao (01-02-2021)“…Aiming at the shortcomings of traditional genetic algorithm in path planning, such as infeasible paths, falling into local optimum, and too many turns, an…”
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Coenzyme Q10 Supplement Rescues Postovulatory Oocyte Aging by Regulating SIRT4 Expression
Published in Current molecular pharmacology (2022)“…High-quality of the oocyte is crucial for embryo development and the success of human-assisted reproduction. The postovulatory aged oocytes lose developmental…”
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