Search Results - "Xie Lihui"
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Effects of sex and aging on the immune cell landscape as assessed by single-cell transcriptomic analysis
Published in Proceedings of the National Academy of Sciences - PNAS (17-08-2021)“…Sex and aging influence the human immune system, resulting in disparate responses to infection, autoimmunity, and cancer. However, the impact of sex and aging…”
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AaWRKY9 contributes to light‐ and jasmonate‐mediated to regulate the biosynthesis of artemisinin in Artemisia annua
Published in The New phytologist (01-09-2021)“…Summary Artemisinin, isolated from Artemisia annua, is recommended as the preferred drug to fight malaria. Previous research showed that jasmonate…”
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Mesenchymal stem cells in allergic diseases: Current status
Published in Allergology international (01-01-2020)“…Allergic diseases, which include asthma, allergic skin diseases, allergic rhinitis and allergic conjunctivitis, have already garnered worldwide public health…”
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A human circulating immune cell landscape in aging and COVID-19
Published in Protein & cell (01-10-2020)“…Age-associated changes in immune cells have been linked to an increased risk for infection. However, a global and detailed characterization of the changes that…”
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An R2R3-MYB Transcription Factor Positively Regulates the Glandular Secretory Trichome Initiation in Artemisia annua L
Published in Frontiers in plant science (09-04-2021)“…L. is known for its specific product "artemisinin" which is an active ingredient for curing malaria. Artemisinin is secreted and accumulated in the glandular…”
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The noncoding and coding transcriptional landscape of the peripheral immune response in patients with COVID‐19
Published in Clinical and translational medicine (01-10-2020)“…Background COVID‐19 is currently a global pandemic, but the response of human immune system to severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)…”
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Multicellular immune dynamics implicate PIM1 as a potential therapeutic target for uveitis
Published in Nature communications (04-10-2022)“…Uveitis is a severe autoimmune disease, and a common cause of blindness; however, its individual cellular dynamics and pathogenic mechanism remain poorly…”
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IL-38: A New Player in Inflammatory Autoimmune Disorders
Published in Biomolecules (Basel, Switzerland) (05-08-2019)“…Interleukin (IL)-38, a newly discovered IL-1 family cytokine, is expressed in several tissues and secreted by various cells. IL-38 has recently been reported…”
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WNT-inhibitory factor 1-mediated glycolysis protects photoreceptor cells in diabetic retinopathy
Published in Journal of translational medicine (06-03-2024)“…In diabetic retinopathy (DR), hypoxia-inducible factor (HIF-1α) induces oxidative stress by upregulating glycolysis. This process leads to neurodegeneration,…”
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Effects of poor sleep on the immune cell landscape as assessed by single-cell analysis
Published in Communications biology (25-11-2021)“…Poor sleep has become an important public health issue. With loss of sleep durations, poor sleep has been linked to the increased risks for diseases. Here we…”
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The Efficacy of Adalimumab as an Initial Treatment in Patients with Behçet’s Retinal Vasculitis
Published in Frontiers in pharmacology (22-06-2021)“…Background: No study has evaluated the effectiveness of Adalimumab (ADA) as first-line in treatment-naïve patients with retinal vasculitis due to Behçet’s…”
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Aging weakens Th17 cell pathogenicity and ameliorates experimental autoimmune uveitis in mice
Published in Protein & cell (01-06-2022)“…Aging-induced changes in the immune system are associated with a higher incidence of infection and vaccination failure. Lymph nodes, which filter the lymph to…”
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Prednisone Reprograms the Transcriptional Immune Cell Landscape in CNS Autoimmune Disease
Published in Frontiers in immunology (13-08-2021)“…Glucocorticoids (GCs) are widely used immunosuppressive drugs for autoimmune diseases, although considerable gaps exist between current knowledge of the…”
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Basic Helix-Loop-Helix Transcription Factors AabHLH2 and AabHLH3 Function Antagonistically With AaMYC2 and Are Negative Regulators in Artemisinin Biosynthesis
Published in Frontiers in plant science (06-06-2022)“…Plants have evolved sophisticated systems for regulating the biosynthesis of specialized phytochemicals. Artemisinin, which is a sesquiterpene lactone widely…”
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Research on Flexible Resource Dynamic Interactive Regulation Technology for Microgrids with High Permeable New Energy
Published in International transactions on electrical energy systems (2023)“…The efficiency of on-site consumption of new energy and the economy of dispatching strategy for that in modern microgrids are increasingly concerning, which…”
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The YABBY Family Transcription Factor AaYABBY5 Directly Targets Cytochrome P450 Monooxygenase (CYP71AV1) and Double-Bond Reductase 2 (DBR2) Involved in Artemisinin Biosynthesis in Artemisia Annua
Published in Frontiers in plant science (10-09-2019)“…Artemisinin is an effective antimalarial sesquiterpene lactone synthesized in Artemisia annua . Various transcription factors have been previously reported…”
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The Transcription Factor Aabzip9 Positively Regulates the Biosynthesis of Artemisinin in Artemisia annua
Published in Frontiers in plant science (07-11-2019)“…Artemisinin-based therapies are the only effective treatment for malaria, which reached to 219 million cases and killed 435,000 people in 2017. To meet the…”
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A high-efficiency Agrobacterium-mediated transient expression system in the leaves of Artemisia annua L
Published in Plant methods (16-10-2021)“…Abstract Background The Agrobacterium -mediated transient transformation, which proved effective in diverse plant species, has been widely applied for…”
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Effectiveness of a smartphone app on improving immunization of children in rural Sichuan Province, China: a cluster randomized controlled trial
Published in BMC public health (31-08-2016)“…The aim of this study was to assess the effectiveness of an EPI smartphone application (EPI app) on improving vaccination coverage in rural Sichuan Province,…”
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AaWRKY17, a positive regulator of artemisinin biosynthesis, is involved in resistance to Pseudomonas syringae in Artemisia annua
Published in Horticulture research (01-10-2021)“…Artemisia annua , a traditional Chinese medicinal plant, remains the only plant source for artemisinin production, yet few genes have been identified to be…”
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