Search Results - "Xie, Zeping"
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Salidroside attenuates neuronal ferroptosis by activating the Nrf2/HO1 signaling pathway in Aβ1-42-induced Alzheimer’s disease mice and glutamate-injured HT22 cells
Published in Chinese medicine (04-07-2022)“…Abstract Background Alzheimer’s disease (AD) is a neurodegenerative disease. Ferroptosis plays a critical role in neurodegenerative diseases. Nuclear factor…”
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2
Salidroside Attenuates Cognitive Dysfunction in Senescence-Accelerated Mouse Prone 8 (SAMP8) Mice and Modulates Inflammation of the Gut-Brain Axis
Published in Frontiers in pharmacology (09-12-2020)“…Alzheimer's disease (AD) is a fatal neurodegenerative disease characterized by progressive cognitive decline and memory loss. However, several therapeutic…”
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3
Baicalin suppresses Propionibacterium acnes-induced skin inflammation by downregulating the NF-κB/MAPK signaling pathway and inhibiting activation of NLRP3 inflammasome
Published in Brazilian journal of medical and biological research (01-01-2020)“…Acne is a kind of common, chronic skin condition caused by the inflammation of the sebaceous glands in hair follicles. Recent studies have demonstrated that…”
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4
Nrf2 regulates iron-dependent hippocampal synapses and functional connectivity damage in depression
Published in Journal of neuroinflammation (21-09-2023)“…Abstract Neuronal iron overload contributes to synaptic damage and neuropsychiatric disorders. However, the molecular mechanisms underlying iron deposition in…”
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5
Cathelicidins from the bullfrog Rana catesbeiana provides novel template for peptide antibiotic design
Published in PloS one (27-03-2014)“…Cathelicidins, a class of gene-encoded effector molecules of vertebrate innate immunity, provide a first line of defense against microbial invasions. Although…”
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6
Design, synthesis, and biological evaluation of triazole-pyrimidine-methylbenzonitrile derivatives as dual A2A/A2B adenosine receptor antagonists
Published in Journal of enzyme inhibition and medicinal chemistry (01-12-2022)“…A series of novel dual A 2A /A 2B AR antagonists based on the triazole-pyrimidine-methylbenzonitrile core were designed and synthesised. The A 2A AR antagonist…”
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7
Selective pyrophosphate detection via metal complexes
Published in iRadiology (Online) (01-12-2023)“…Pyrophosphate (PPi) anions are crucial in numerous biological and ecological processes involved in energy conversion, enzymatic reactions, and metabolic…”
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The anti-tumor efficacy of 20(S)-protopanaxadiol, an active metabolite of ginseng, according to fasting on hepatocellular carcinoma
Published in Journal of ginseng research (01-01-2022)“…20(S)-protopanaxadiol (20(S)-PPD), one of the main active metabolites of ginseng, performs a broad spectrum of anti-tumor effects. Our aims are to search out…”
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9
Ring D-Modified and Highly Reduced Angucyclinones From Marine Sediment-Derived Streptomyces sp
Published in Frontiers in chemistry (12-10-2021)“…Angucyclines and angucyclinones represent the largest family of type II PKS-engineered natural products. Chemical analysis of a marine Streptomyces sp. KCB-132…”
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10
Antibacterial and Cytotoxic Bridged and Ring Cleavage Angucyclinones From a Marine Streptomyces sp
Published in Frontiers in chemistry (04-08-2020)“…Chemical investigation of a marine-derived Streptomyces sp. KCB-132, cultivated in liquid ISP2 medium, had led to the discovery of three C-ring cleavage…”
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11
Genomic sequence-based discovery of novel angucyclinone antibiotics from marine Streptomyces sp. W007
Published in FEMS microbiology letters (01-07-2012)“…Abstract A large number of novel bioactive compounds were discovered from microbial secondary metabolites based on the traditional bioactivity screenings…”
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12
The anti-tumor efficacy of 20(S)-protopanaxadiol, an active metabolite of ginseng, according to fasting on hepatocellular carcinoma
Published in Journal of ginseng research (2022)“…Background: 20(S)-protopanaxadiol (20(S)-PPD), one of the main active metabolites of ginseng, performs a broad spectrum of anti-tumor effects. Our aims are to…”
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13
Isolation, identification, and cytotoxicity of a new isobenzofuran derivative from marine Streptomyces sp. W007
Published in Chinese journal of oceanology and limnology (01-03-2016)“…A new isobenzofuran derivative (1) was isolated from the marine Streptomyces sp. W007 and its structure was determined through extensive spectroscopic…”
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14
Kiamycin, a unique cytotoxic angucyclinone derivative from a marine Streptomyces sp
Published in Marine drugs (01-03-2012)“…Kiamycin (1), a new angucyclinone derivative possessing an 1,12-epoxybenz[a]anthracene ring system, was isolated from the marine Streptomyces sp. strain M268…”
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15
A new anthracene derivative from marine Streptomyces sp. W007 exhibiting highly and selectively cytotoxic activities
Published in Marine drugs (01-09-2011)“…A new anthracene derivative, 3-hydroxy-1-keto-3-methyl-8-methoxy-1,2,3, 4-tetrahydro-benz[α]anthracene, was isolated from the marine strain Streptomyces sp…”
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16
A marine sulfate-reducing bacterium producing multiple antibiotics: biological and chemical investigation
Published in Marine drugs (21-07-2009)“…A marine sulfate-reducing bacterium SRB-22 was isolated by means of the agar shake dilution method and identified as Desulfovibrio desulfuricans by…”
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Effects of hypoxia in the gills of the Manila clam Ruditapes philippinarum using NMR-based metabolomics
Published in Marine pollution bulletin (15-01-2017)“…Coastal hypoxia affects the survival, behavior, and reproduction of individual local marine organisms, and the abundance, biomass, and biodiversity of coastal…”
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18
Salidroside alleviates cognitive impairment by inhibiting ferroptosis via activation of the Nrf2/GPX4 axis in SAMP8 mice
Published in Phytomedicine (Stuttgart) (01-06-2023)“…Alzheimer's disease (AD) is a neurogenerative disease and remains no effective method for stopping its progress. Ferroptosis and adaptive immunity have been…”
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Research progress and application of chitosan dressings in hemostasis: A review
Published in International journal of biological macromolecules (01-12-2024)“…Hemorrhage affects human health, and severe bleeding remains a leading contributor to trauma-related mortality. The speed and effectiveness of the application…”
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20
A dual-mode mechanism terpyridine-based fluorescent probe (Tpy-Zn) for ATP sensing
Published in Journal of molecular structure (05-05-2024)“…•We report a simple terpyridine-based probe (Tpy-Zn) for ATP-selective turn-on sensing that exhibits good fluorescence-enhanced recognition of ATP in…”
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