Search Results - "Xie, Yong Mei"
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Mitochondria-targeted ratiometric fluorescent probe for real time monitoring of pH in living cells
Published in Biomaterials (01-06-2015)“…Abstract Pyridinium functioned 7-hydroxy coumarin was presented as the first mitochondria-targeted ratiometric fluorescent probe CP for real time monitoring pH…”
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A highly selective water-soluble optical probe for endogenous peroxynitrite
Published in Chemical communications (Cambridge, England) (07-09-2014)“…A colorimetric and fluorescent probe C-Py-1 for ONOO(-) was prepared and it could exhibit high sensitivity and excellent selectivity toward ONOO(-) among…”
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Enantioselective [4 + 2] Cycloaddition of Cyclic N‑Sulfimines and Acyclic Enones or Ynones: A Concise Route to Sulfamidate-Fused 2,6-Disubstituted Piperidin-4-ones
Published in Organic letters (06-12-2013)“…A concise route to valuable sulfamate-fused 2,6-disubstituted piperidin-4-ones or 2,3-dihydropyridin-4(1H)-ones in good yield with high diastereo- and…”
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Paternal origin of Tungusic‐speaking populations: Insights from the updated phylogenetic tree of Y‐chromosome haplogroup C2a‐M86
Published in American journal of human biology (01-03-2021)“…Objectives Haplogroup C2a‐M48 is the predominant paternal lineage of Tungusic‐speaking populations, one of the largest population groups in Siberia. Up until…”
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SIS3, a good candidate for the reverse of type 2 diabetes mellitus in mice
Published in Fundamental & clinical pharmacology (01-04-2021)“…TGF‐β signaling plays an extremely important role in the occurrence and development of type 2 diabetes mellitus (T2DM), and the blockade of TGF‐β/Smad3 pathway…”
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Inhibition of Stat3 signaling pathway by nifuroxazide improves antitumor immunity and impairs colorectal carcinoma metastasis
Published in Cell death & disease (05-01-2017)“…Colorectal carcinoma (CRC) is the one of the most common cancers with considerable metastatic potential, explaining the need for new drug candidates that…”
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Phylogenetic analysis of the Y-chromosome haplogroup C2b-F1067, a dominant paternal lineage in Eastern Eurasia
Published in Journal of human genetics (01-10-2020)“…Human Y-chromosome haplogroup C2b-F1067 is one of the dominant paternal lineages of populations in Eastern Eurasia. In order to explore the origin,…”
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Discovery of highly potent and selective 7-ethyl-10-hydroxycamptothecin-glucose conjugates as potential anti-colorectal cancer agents
Published in Frontiers in pharmacology (23-11-2022)“…7-Ethyl-10-hydroxycamptothecin (SN38), a highly potent metabolite of irinotecan, has an anticancer efficacy 100-1000 folds more than irinotecan . However, the…”
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9
Novel Tumor-Specific and Mitochondria-Targeted near-Infrared-Emission Fluorescent Probe for SO2 Derivatives in Living Cells
Published in ACS sensors (26-02-2016)“…Endogenous sulfur dioxide (SO2) is an important gaseous signal molecule, which was also regarded as one of the reactive sulfur spaces (RSS) and closely related…”
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Reduced thiamine binding is a novel mechanism for TPK deficiency disorder
Published in Molecular genetics and genomics : MGG (01-04-2019)“…Thiamine pyrophosphokinase (TPK) converts thiamine (vitamin B 1 ) into thiamine pyrophosphate (TPP), an essential cofactor for many important enzymes. TPK1…”
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Action Mechanism Underlying Improvement Effect of Fuzi Lizhong Decoction on Nonalcoholic Fatty Liver Disease: A Study Based on Network Pharmacology and Molecular Docking
Published in Evidence-based complementary and alternative medicine (2022)“…Objective. This study aimed to decipher the bioactive compounds and potential mechanism of traditional Chinese medicine (TCM) formula Fuzi Lizhong Decoction…”
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12
Intestinal ischemia-reperfusion of macaques triggers a strong innate immune response
Published in World journal of gastroenterology : WJG (07-11-2014)“…AIM:To investigate inflammatory injury in the intestinal mucosa after intestinal ischemia-reperfusion(ⅡR) with Toll-like receptor(TLR)-mediated innate…”
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Global attitudes on and the status of enteral nutrition therapy for pediatric inflammatory bowel disease
Published in Frontiers in medicine (08-12-2022)“…Enteral nutrition (EN) is a diet-remission therapy for inflammatory bowel disease (IBD) that plays a more important role in children than adults. EN includes…”
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Adjuvant celecoxib and lanreotide following transarterial chemoembolisation for unresectable hepatocellular carcinoma: a randomized pilot study
Published in Oncotarget (18-07-2017)“…Recurrence of hepatocellular carcinoma (HCC) after transarterial chemoembolisation (TACE) is common due to neoangiogenesis. Cyclooxygenase-2 inhibitors and…”
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Efficient and mild one-pot synthesis of (E)-8′-arylidene-5′,6′,7′,8′-tetrahydrospiro[oxindole-3,4′-pyrano[3,2-c]pyridin] derivatives with potential antitumor activity
Published in Arabian journal of chemistry (01-12-2019)“…A mild and efficient cyclization procedure for the synthesis of (E)-8′-arylidene-5′,6′,7′,8′-tetrahydrospiro[oxindole-3,4′-pyrano[3,2-c]pyridin] derivatives…”
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Efficient and mild cyclization procedures for the synthesis of novel 2-amino-4H-pyran derivatives with potential antitumor activity
Published in Chinese chemical letters (01-07-2014)“…A series of novel 2-amino-4H-pyran derivatives have been synthesized via a three-component reaction of α,β-unsaturated ketone derivatives, malononitrile,…”
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A mitochondria-targeted colorimetric and ratiometric fluorescent probe for biological SO2 derivatives in living cells
Published in Chemical communications (Cambridge, England) (25-06-2015)“…A ratiometric fluorescent probe for SO2 derivatives based on the conjugate of carbazole and indolium was presented, which could selectively respond to HSO3(-)…”
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Facile Synthesis of Functionalized Spiropyrrolizidine Oxindoles via a Three-Component Tandem Cycloaddition Reaction
Published in Molecules (Basel, Switzerland) (01-10-2011)“…An efficient synthesis of functionalized spiropyrrolizidine oxindoles via a three-component tandem cycloaddition has been achieved. This strategy can provide…”
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Mitochondria-targeted colorimetric and fluorescent probes for hypochlorite and their applications for in vivo imaging
Published in Chemical communications (Cambridge, England) (14-08-2014)“…Two mitochondria-targeted real-time probes were presented, which could selectively respond to hypochlorite over other ROS. Meanwhile, the "off-on" probes could…”
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Synthesis and biological evaluation of novel acenaphthene derivatives as potential antitumor agents
Published in Molecules (Basel, Switzerland) (17-03-2011)“…Twelve novel acenaphthene derivatives have been synthesized. The structures of all compounds were confirmed by ¹H-NMR, MS and elemental analysis. Their…”
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