Search Results - "Xie, Yingda"
-
1
Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre diagnostic accuracy study
Published in The Lancet infectious diseases (01-01-2018)“…The Xpert MTB/RIF assay is an automated molecular test that has improved the detection of tuberculosis and rifampicin resistance, but its sensitivity is…”
Get full text
Journal Article -
2
Persistence of SARS-CoV-2 in saliva: Implications for late-stage diagnosis and infectious duration
Published in PloS one (16-03-2023)“…Saliva has been a COVID-19 diagnostic specimen of interest due to its simple collection, scalability, and yield. Yet COVID-19 testing and estimates of the…”
Get full text
Journal Article -
3
Alternative Methods for Therapeutic Drug Monitoring and Dose Adjustment of Tuberculosis Treatment in Clinical Settings: A Systematic Review
Published in Clinical pharmacokinetics (01-03-2023)“…Background and Objective Quantifying exposure to drugs for personalized dose adjustment is of critical importance in patients with tuberculosis who may be at…”
Get full text
Journal Article -
4
Development and Validation of a UPLC-MS/MS Method for Therapeutic Drug Monitoring, Pharmacokinetic and Stability Studies of First-Line Antituberculosis Drugs in Urine
Published in Molecules (Basel, Switzerland) (01-01-2024)“…Tuberculosis (TB) remains one of the leading global causes of mortality. Several methods have been established to detect anti-TB agents in human plasma and…”
Get full text
Journal Article -
5
New approach to rifampicin stability and first-line anti-tubercular drug pharmacokinetics by UPLC-MS/MS
Published in Journal of pharmaceutical and biomedical analysis (25-10-2023)“…Successful tuberculosis (TB) therapy requires achieving sufficient exposure to multiple drugs. Limited stability of several first-line anti-TB drugs might…”
Get full text
Journal Article -
6
Evaluation of a Rapid Molecular Drug-Susceptibility Test for Tuberculosis
Published in The New England journal of medicine (14-09-2017)“…Increasing drug resistance in Mycobacterium tuberculosis complicates the management of tuberculosis. Development of a point-of-care test to determine drug…”
Get full text
Journal Article -
7
Sample collection and transport strategies to enhance yield, accessibility, and biosafety of COVID-19 RT-PCR testing
Published in Journal of medical microbiology (01-09-2021)“…Non-invasive sample collection and viral sterilizing buffers have independently enabled workflows for more widespread COVID-19 testing by reverse-transcriptase…”
Get full text
Journal Article -
8
Simplified urine-based method to detect rifampin underexposure in adults with tuberculosis: a prospective diagnostic accuracy study
Published in Antimicrobial agents and chemotherapy (15-11-2023)“…Variable pharmacokinetics of rifampin in tuberculosis (TB) treatment can lead to poor outcomes. Urine spectrophotometry is simpler and more accessible than…”
Get full text
Journal Article -
9
RT-PCR negative COVID-19
Published in BMC infectious diseases (13-02-2022)“…COVID-19 is a multi-system infection with emerging evidence-based antiviral and anti-inflammatory therapies to improve disease prognosis. However, a subset of…”
Get full text
Journal Article -
10
Duration of Symptoms Prior to Pediatric and Adolescent Tuberculosis Diagnosis and Its Impact on Schooling in Tanzania: A Mixed Methods Study
Published in The American journal of tropical medicine and hygiene (07-06-2023)“…At least a third of tuberculosis (TB) cases remain undiagnosed, disproportionately so in children and adolescents, which is hampering global elimination goals…”
Get full text
Journal Article -
11
Fourteen-day PET/CT imaging to monitor drug combination activity in treated individuals with tuberculosis
Published in Science translational medicine (03-02-2021)“…Early bactericidal activity studies monitor daily sputum bacterial counts in individuals with tuberculosis (TB) for 14 days during experimental drug treatment…”
Get more information
Journal Article -
12
Rifampin urinary excretion to predict serum targets in children with tuberculosis: a prospective diagnostic accuracy study
Published in Archives of disease in childhood (01-08-2023)“…ObjectivePharmacokinetic variability drives tuberculosis (TB) treatment outcomes but measurement of serum drug concentrations for personalised dosing is…”
Get full text
Journal Article -
13
A randomized controlled trial to evaluate outcomes with Aggrenox in patients with SARS-CoV-2 infection
Published in PloS one (30-01-2023)“…Coronavirus disease 2019 (COVID-19) is an immunoinflammatory and hypercoagulable state that contributes to respiratory distress, multi-organ dysfunction, and…”
Get full text
Journal Article -
14
Classification of early tuberculosis states to guide research for improved care and prevention: an international Delphi consensus exercise
Published in The lancet respiratory medicine (01-06-2024)“…The current active–latent paradigm of tuberculosis largely neglects the documented spectrum of disease. Inconsistency with regard to definitions, terminology,…”
Get full text
Journal Article -
15
Transmission of Mycobacterium tuberculosis From Patients Who Are Nucleic Acid Amplification Test Negative
Published in Clinical infectious diseases (13-11-2018)“…We assessed the transmission risk of pulmonary tuberculosis patients whose sputum nucleic acid amplification tests (NAAT) were negative. We estimated that, at…”
Get full text
Journal Article -
16
Linezolid Trough Concentrations Correlate with Mitochondrial Toxicity-Related Adverse Events in the Treatment of Chronic Extensively Drug-Resistant Tuberculosis
Published in EBioMedicine (01-11-2015)“…Long-term linezolid use is limited by mitochondrial toxicity-associated adverse events (AEs). Within a prospective, randomized controlled trial of linezolid to…”
Get full text
Journal Article -
17
Severe Paradoxical Reaction During Treatment of Disseminated Tuberculosis in a Patient With Neutralizing Anti-IFNγ Autoantibodies
Published in Clinical infectious diseases (15-03-2016)“…Interferon-gamma (IFNγ) neutralizing autoantibodies are associated with disseminated nontuberculous mycobacterial infections. We report a previously healthy…”
Get full text
Journal Article -
18
Highly versatile antibody binding assay for the detection of SARS-CoV-2 infection and vaccination
Published in Journal of immunological methods (01-12-2021)“…Monitoring the burden and spread of infection with the new coronavirus SARS-CoV-2, whether within small communities or in large geographical settings, is of…”
Get full text
Journal Article -
19
Renal Fanconi syndrome with meropenem/amoxicillin-clavulanate during treatment of extensively drug-resistant tuberculosis
Published in The European respiratory journal (01-12-2017)“…We read with interest the papers by Tiberi et al. [1, 2] describing the effectiveness of meropenem/clavulanate in treating multidrug-resistant (MDR) and…”
Get full text
Journal Article -
20
Xpert MTB/RIF Ultra versus mycobacterial growth indicator tube liquid culture for detection of Mycobacterium tuberculosis in symptomatic adults: a diagnostic accuracy study
Published in The Lancet. Microbe (01-06-2024)“…Xpert MTB/RIF Ultra (Ultra) is an automated molecular test for the detection of Mycobacterium tuberculosis in sputum. We compared the sensitivity of Ultra to…”
Get full text
Journal Article