Search Results - "Xie, Walter"
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Quality by Design I: Application of Failure Mode Effect Analysis (FMEA) and Plackett–Burman Design of Experiments in the Identification of “Main Factors” in the Formulation and Process Design Space for Roller-Compacted Ciprofloxacin Hydrochloride Immediate-Release Tablets
Published in AAPS PharmSciTech (01-12-2012)“…As outlined in the ICH Q8(R2) guidance, identifying the critical quality attributes (CQA) is a crucial part of dosage form development; however, the number of…”
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Novel, potent and selective cyclin D1/CDK4 inhibitors: indolo[6,7- a]pyrrolo[3,4- c]carbazoles
Published in Bioorganic & medicinal chemistry letters (21-07-2003)“…The synthesis and CDK inhibitory properties of a series of indolo[6,7- a]pyrrolo[3,4- c]carbazoles is reported. In addition to their potent CDK activity, the…”
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Fuzzy prototype model and semantic distance
Published in Information systems (Oxford) (01-11-2007)“…It is a challenge to provide an intelligent product suggestion for these new customers without previous shopping records in the supermarket application. To…”
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RG3487, a novel nicotinic α7 receptor partial agonist, improves cognition and sensorimotor gating in rodents
Published in The Journal of pharmacology and experimental therapeutics (01-01-2011)“…Neuronal nicotinic α7 acetylcholine receptors (α7nAChRs) are expressed primarily in the brain and are implicated in modulating many cognitive functions (e.g.,…”
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Intelligent Fril/SQL interrogator
Published in International journal of intelligent systems (01-03-2007)“…The intelligent Fril/SQL interrogator is an object‐oriented and knowledge‐based support query system, which is implemented by the set of logic objects linking…”
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