Search Results - "Xie, Qiqiang"

Efficient Difluoromethylation of Alcohols Using TMSCF2Br as a Unique and Practical Difluorocarbene Reagent under Mild Conditions by Xie, Qiqiang, Ni, Chuanfa, Zhang, Rongyi, Li, Lingchun, Rong, Jian, Hu, Jinbo

“…A general method for the efficient difluoromethylation of alcohols using commercially available TMSCF2Br (TMS=trimethylsilyl) as a unique and practical…”
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TMSCF3 as a Convenient Source of CF2=CF2 for Pentafluoroethylation, (Aryloxy)tetrafluoroethylation, and Tetrafluoroethylation by Li, Lingchun, Ni, Chuanfa, Xie, Qiqiang, Hu, Mingyou, Wang, Fei, Hu, Jinbo

“…A new method for the on‐site preparation of tetrafluoroethylene (TFE) and a procedure for its efficient use in pentafluoroethylation by fluoride addition were…”
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Morusin, a novel inhibitor of ACLY, induces mitochondrial apoptosis in hepatocellular carcinoma cells through ROS-mediated mitophagy by Li, Desheng, Yuan, Xiaoqing, Ma, Jianjun, Lu, Tao, Zhang, Jinjin, Liu, Huan, Zhang, Guanqing, Wang, Yue, Liu, Xiaohan, Xie, Qiqiang, Zhou, Ling, Xu, Maolei

“…Morusin (Mor), a prenylated flavonoid isolated from the root bark of Morus alba L., exhibits potent anti-tumour effects; however, the molecular target of Mor…”
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Copper-Mediated Deuterotrifluoromethylation of α-Diazo Esters by Hu, Mingyou, Xie, Qiqiang, Li, Xinjin, Ni, Chuanfa, Hu, Jinbo

“…A copper-mediated deuterotrifluoromethylation of α-diazo esters under the promotion of deuterium oxide （D20） has been developed for the synthesis of…”
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Aza-Matteson Reactions via Controlled Mono- and Double-Methylene Insertions into Nitrogen–Boron Bonds by Xie, Qiqiang, Dong, Guangbin

“…Boron-homologation reactions represent an efficient and programmable approach to prepare alkylboronates, which are valuable and versatile synthetic…”
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A Journey of the Development of Privileged Difluorocarbene Reagents TMSCF2X (X = Br, F, Cl) for Organic Synthesis by Xie, Qiqiang, Hu, Jinbo

“…Conspectus As fluorine has played an increasingly important role in modulating the physical, chemical, and biological properties of organic molecules, the…”
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Programmable Ether Synthesis Enabled by Oxa-Matteson Reaction by Xie, Qiqiang, Dong, Guangbin

“…The Matteson-type reactions have received increasing interest in constructing complex organic molecules via iterative synthetic strategies; however, the…”
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Chen's Reagent: A Versatile Reagent for Trifluoromethylation, Difluoromethylenation, and Difluoroalkylation in Organic Synthesis by Xie, Qiqiang, Hu, Jinbo

“…Summary Methyl fluorosulfonyldifluoroacetate (FSO2CF2CO2Me or MFSDA), often called “Chen's reagent”, is commonly used to synthesize trifluoromethylated and…”
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A Journey of the Development of Privileged Difluorocarbene Reagents TMSCF 2 X (X = Br, F, Cl) for Organic Synthesis by Xie, Qiqiang, Hu, Jinbo

“…ConspectusAs fluorine has played an increasingly important role in modulating the physical, chemical, and biological properties of organic molecules, the…”
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TMSCF3 as a Convenient Source of CF2=CF2 for Pentafluoroethylation, (Aryloxy)tetrafluoroethylation, and Tetrafluoroethylation by Li, Lingchun, Ni, Chuanfa, Xie, Qiqiang, Hu, Mingyou, Wang, Fei, Hu, Jinbo

“…A new method for the on‐site preparation of tetrafluoroethylene (TFE) and a procedure for its efficient use in pentafluoroethylation by fluoride addition were…”
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Efficient Difluoromethylation of Alcohols Using TMSCF2Br as a Unique and Practical Difluorocarbene Reagent under Mild Conditions by Xie, Qiqiang, Ni, Chuanfa, Zhang, Rongyi, Li, Lingchun, Rong, Jian, Hu, Jinbo

“…A general method for the efficient difluoromethylation of alcohols using commercially available TMSCF2Br (TMS=trimethylsilyl) as a unique and practical…”
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Regioselective Synthesis of 2,6-Dimethyl-3,5-bis[（3-aryl-5- trifluoromethyl）-isoxazol-4-carbonyl]-pyridine Derivatives by Yang, Yindi, Zhang, Min, Zhu, Yiwen, Zhang, Li, Xie, Qiqiang, Song, Liping, Deng, Hongmei

“…Ethyl 4,4,4-trifluoro-3-oxo-butyrate reacted with 2,6-dimethyl-3,5-diacetyl-pyridine 1 in the presence of NaOC2H5 at 0 ℃ to give…”
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Programmable Amine Synthesis via Iterative Boron Homologation by Xie, Qiqiang, Zhang, Rui, Dong, Guangbin

“…The value of Matteson‐type reactions has been increasingly recognized for developing automated organic synthesis. However, the typical Matteson reactions…”
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A General Protocol for C−H Difluoromethylation of Carbon Acids with TMSCF2Br by Xie, Qiqiang, Zhu, Ziyue, Li, Lingchun, Ni, Chuanfa, Hu, Jinbo

“…An efficient method for the selective C‐difluoromethylation of carbon acids with the reagent TMSCF2Br has been developed. A variety of structurally diverse…”
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TMSCF2Br‐Enabled Fluorination–Aminocarbonylation of Aldehydes: Modular Access to α‐Fluoroamides by Liu, An, Ni, Chuanfa, Xie, Qiqiang, Hu, Jinbo

“…A protocol for the modular assembly of the α‐fluoroamide motif has been developed, which provides a practical method for the efficient synthesis of…”
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Transition‐Metal‐Free Controllable Single and Double Difluoromethylene Formal Insertions into C−H Bonds of Aldehydes with TMSCF2Br by Liu, An, Ni, Chuanfa, Xie, Qiqiang, Hu, Jinbo

“…We have developed a new strategy for controllable single and double difluoromethylene (CF2) formal insertions into C−H bonds of aldehydes with nearly full…”
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Nucleophilic (Phenylsulfonyl/arylthio)difluoromethylation of Aldehydes with TMSCF2Br: A Three-Component Strategy by Xie, Qiqiang, Zhu, Ziyue, Ni, Chuanfa, Hu, Jinbo

“…An efficient method for nucleophilic (phenylsulfonyl/arylthio)­difluoromethylation of aldehydes with TMSCF2Br was developed. The reaction proceeds through in…”
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Difluorocarbene‐Induced Ring‐Opening Difluoromethylation‐Halogenation of Cyclic (Thio)Ethers with TMSCF2X (X=Br, Cl) by Zhang, Rongyi, Li, Qigang, Xie, Qiqiang, Ni, Chuanfa, Hu, Jinbo

“…The ring‐opening difluoromethylation‐halogenation of cyclic (thio)ethers is reported through a simple strategy relying on carbon‐chalcogen bond activation with…”
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Transition-Metal-Free Controllable Single and Double Difluoromethylene Formal Insertions into C-H Bonds of Aldehydes with TMSCF 2 Br by Liu, An, Ni, Chuanfa, Xie, Qiqiang, Hu, Jinbo

“…We have developed a new strategy for controllable single and double difluoromethylene (CF ) formal insertions into C-H bonds of aldehydes with nearly full…”
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Controllable double CF2-insertion into sp2 C–Cu bond using TMSCF3: a facile access to tetrafluoroethylene-bridged structures by Xie, Qiqiang, Zhu, Ziyue, Li, Lingchun, Ni, Chuanfa, Hu, Jinbo

“…A highly efficient method for controllable double CF2-insertion into pentafluorophenylcopper species using TMSCF3 as difluoromethylene source has been…”
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