Search Results - "Xie, Mengru"
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Circadian Clock Gene Bmal1 Inhibits Tumorigenesis and Increases Paclitaxel Sensitivity in Tongue Squamous Cell Carcinoma
Published in Cancer research (Chicago, Ill.) (15-01-2017)“…Circadian clock genes regulate cancer development and chemotherapy susceptibility. Accordingly, chronotherapy based on circadian phenotypes might be applied to…”
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New Insights Into the Circadian Rhythm and Its Related Diseases
Published in Frontiers in physiology (25-06-2019)“…Circadian rhythms (CR) are a series of endogenous autonomous oscillators generated by the molecular circadian clock which acting on coordinating internal time…”
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3
Role of the oral microbiota in cancer evolution and progression
Published in Cancer medicine (Malden, MA) (01-09-2020)“…Bacteria identified in the oral cavity are highly complicated. They include approximately 1000 species with a diverse variety of commensal microbes that play…”
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4
The roles of osteocytes in alveolar bone destruction in periodontitis
Published in Journal of translational medicine (11-12-2020)“…Periodontitis, a bacterium-induced inflammatory disease that is characterized by alveolar bone loss, is highly prevalent worldwide. Elucidating the underlying…”
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The crystal structure of (E)-3-(2-chlorophenyl)-1-ferrocenylprop-2-en-1-one, C19H15ClFeO
Published in Zeitschrift für Kristallographie. New crystal structures (26-08-2022)“…ClFeO, triclinic, (no. 2), = 10.2693(5) Å, = 11.2568(6) Å, = 20.8930(10) Å, = 80.350(2)°, = 76.9640(10)°, = 86.921(2)°, = 2319.4(2) Å , = 6,…”
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PLAU Promotes Cell Proliferation and Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma
Published in Frontiers in genetics (20-05-2021)“…Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. However, the biological…”
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The Effects of Porphyromonas gingivalis on Atherosclerosis-Related Cells
Published in Frontiers in immunology (23-12-2021)“…Atherosclerosis (AS), one of the most common types of cardiovascular disease, has initially been attributed to the accumulation of fats and fibrous materials…”
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Circadian rhythm modulates endochondral bone formation via MTR1/AMPKβ1/BMAL1 signaling axis
Published in Cell death and differentiation (01-04-2022)“…The circadian clock is a master regulator in coordinating daily oscillations of physiology and behaviors. Nevertheless, how the circadian rhythm affects…”
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9
Porphyromonas gingivalis and Its Systemic Impact: Current Status
Published in Pathogens (Basel) (13-11-2020)“…The relationship between periodontitis and systemic diseases, notably including atherosclerosis and diabetes, has been studied for several years. Porphyromonas…”
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Porphyromonas gingivalis disrupts vascular endothelial homeostasis in a TLR-NF-κB axis dependent manner
Published in International journal of oral science (30-09-2020)“…Cardiovascular disease is still the leading cause of mortality worldwide. Vascular endothelial dysfunction is viewed as the initial step of most cardiovascular…”
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FBXO2 targets glycosylated SUN2 for ubiquitination and degradation to promote ovarian cancer development
Published in Cell death & disease (07-05-2022)“…SAD1/UNC84 domain protein-2 (SUN2) plays a tumor suppressor role in various types of cancer by inhibiting cancer cell proliferation, migration and promoting…”
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12
Ecological Niche Characteristics of the Diets of Three Sympatric Rodents in the Meili Snow Mountain, Yunnan
Published in Animals (Basel) (18-08-2024)“…Understanding the dietary preferences and ecological niche characteristics of mammals not only reveals their adaptive strategies under environmental changes…”
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13
The Roles of Periodontal Bacteria in Atherosclerosis
Published in International journal of molecular sciences (01-08-2023)“…Atherosclerosis (AS) is an inflammatory vascular disease that constitutes a major underlying cause of cardiovascular diseases (CVD) and stroke. Infection is a…”
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14
Application of recombinase polymerase amplification with lateral flow assay to pathogen point-of-care diagnosis
Published in Frontiers in cellular and infection microbiology (18-11-2024)“…Since the outbreak of the new coronavirus, point-of-care diagnostics based on nucleic acid testing have become a requirement for the development of pathogen…”
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Periodic Oxaliplatin Administration in Synergy with PER2‐Mediated PCNA Transcription Repression Promotes Chronochemotherapeutic Efficacy of OSCC
Published in Advanced science (01-11-2019)“…Developing chemotherapeutic resistance affects clinical outcomes of oxaliplatin treatment on various types of cancer. Thus, it is imperative to explore…”
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WXJ-202, a novel Ribociclib derivative, exerts antitumor effects against breast cancer through CDK4/6
Published in Frontiers in pharmacology (19-01-2023)“…Cyclin-dependent kinases 4 and 6 ( ) are key regulatory proteins in the cell division and proliferative cycle in humans. They are overactive in many malignant…”
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The osteoclastic activity in apical distal region of molar mesial roots affects orthodontic tooth movement and root resorption in rats
Published in International journal of oral science (28-02-2024)“…The utilization of optimal orthodontic force is crucial to prevent undesirable side effects and ensure efficient tooth movement during orthodontic treatment…”
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VHL-HIF-2α axis-induced SEMA6A upregulation stabilized β-catenin to drive clear cell renal cell carcinoma progression
Published in Cell death & disease (04-02-2023)“…SEMA6A is a multifunctional transmembrane semaphorin protein that participates in various cellular processes, including axon guidance, cell migration, and…”
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The crystal structure of ( E )-3-(2-chlorophenyl)-1-ferrocenylprop-2-en-1-one, C 19 H 15 ClFeO
Published in Zeitschrift für Kristallographie. New crystal structures (26-08-2022)“…Abstract C 19 H 15 ClFeO, triclinic, P 1 ‾ $P\overline{1}$ (no. 2), a = 10.2693(5) Å, b = 11.2568(6) Å, c = 20.8930(10) Å, α = 80.350(2)°, β…”
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BMAL1-Downregulation Aggravates Porphyromonas Gingivalis-Induced Atherosclerosis by Encouraging Oxidative Stress
Published in Circulation research (13-03-2020)“…Atherosclerotic cardiovascular diseases are the leading cause of mortality worldwide. Atherosclerotic cardiovascular diseases are considered as chronic…”
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