Search Results - "Xie, Linka"
-
1
FOXO1 is a tumor suppressor in classical Hodgkin lymphoma
Published in Blood (12-04-2012)“…The FOXO transcription factors control proliferation and apoptosis in different cell types. Their activity is regulated by posttranslational modifications,…”
Get full text
Journal Article -
2
FOXO1 inhibits osteoclastogenesis partially by antagnozing MYC
Published in Scientific reports (16-11-2015)“…FOXO transcription factors especially FOXO1 have profound roles in bone development and remodeling. The regulation of cells of the osteoblast lineage by FOXOs…”
Get full text
Journal Article -
3
KLF4 is a tumor suppressor in B-cell non-Hodgkin lymphoma and in classic Hodgkin lymphoma
Published in Blood (02-09-2010)“…The transcription factor KLF4 may act both as an oncogene and a tumor suppressor in a tissue-depending manner. In T- and pre-B-cell lymphoma, KLF4 was found to…”
Get full text
Journal Article -
4
Repression of TCF3/E2A contributes to Hodgkin lymphomagenesis
Published in Oncotarget (14-06-2016)“…Although Hodgkin and Reed-Sternberg (HRS) cells of classical Hodgkin lymphoma (cHL) derived from germinal or post germinal B cells, they have lost the B cell…”
Get full text
Journal Article -
5
FOXO1 repression contributes to block of plasma cell differentiation in classical Hodgkin lymphoma
Published in Blood (13-11-2014)“…The survival of classical Hodgkin lymphoma (cHL) cells depends on activation of NF-κB, JAK/STAT, and IRF4. Whereas these factors typically induce the master…”
Get full text
Journal Article -
6
The effect of mucA allele on biofilm architecture and the biofilm-related proteomes
Published in African journal of biotechnology (29-08-2011)“…In this study, a unique mucA mutation (designated mucA56) was introduced, which was characterized by deletion of bases 166-333, encoding MucA56 protein with…”
Get full text
Journal Article -
7
A Novel Defined Pyroptosis-Related Gene Signature for the Prognosis of Acute Myeloid Leukemia
Published in Genes (03-12-2022)“…Pyroptosis is an inflammatory form of programmed necrotic cell death, but its potential prognostic value in acute myeloid leukemia (AML) remains unclear. On…”
Get full text
Journal Article -
8
A Competing Risk-based Prognostic Model to Predict Cancer-specific Death of Patients with Spinal and Pelvic Chondrosarcoma
Published in Spine (Philadelphia, Pa. 1976) (15-11-2021)“…Study Design. Retrospective analysis. Objective. The aim of this study was to develop and validate a competing-risk-based prognostic model and a nomogram for…”
Get full text
Journal Article -
9
AGTR1 promotes lymph node metastasis in breast cancer by upregulating CXCR4/SDF-1α and inducing cell migration and invasion
Published in Aging (Albany, NY.) (19-06-2019)“…The angiotensin II type I receptor (AGTR1) has a strong influence on tumor growth, angiogenesis, inflammation and immunity. However, the role of AGTR1 on lymph…”
Get full text
Journal Article -
10
Right atrial epithelioid angiosarcoma with multiple pulmonary metastasis confirmed by multimodality imaging-guided pulmonary biopsy: A case report and literature review
Published in Medicine (Baltimore) (01-07-2018)“…Primary cardiac tumors are very rare, and angiosarcoma accounts for about 33% of all primary malignant cardiac tumors. Primary cardiac epithelioid angiosarcoma…”
Get full text
Journal Article -
11
Decitabine represses translocated MYC oncogene in Burkitt lymphoma
Published in The Journal of pathology (01-04-2013)“…Burkitt lymphoma (BL) is caused by translocation of the MYC gene to an immunoglobulin locus resulting in its constitutive expression depending on the activity…”
Get full text
Journal Article -
12
Fine-tuning of FOXO3A in cHL as a survival mechanism and a hallmark of abortive plasma cell differentiation
Published in Blood (05-04-2018)“…We recently found that FOXO1 repression contributes to the oncogenic program of classical Hodgkin lymphoma (cHL). Interestingly, FOXO3A, another member of the…”
Get full text
Journal Article -
13
Preoperative platelet to lymphocyte ratio is a valuable prognostic biomarker in patients with colorectal cancer
Published in Oncotarget (03-05-2016)“…Recent studies suggest that an elevated preoperative platelet to lymphocyte ratio (PLR) may be considered a poor prognostic biomarker in patients with…”
Get full text
Journal Article -
14
Downregulation Of FOXO1 Prevents Induction Of The Tumor Suppressor BLIMP-1 In Classical Hodgkin Lymphoma
Published in Blood (15-11-2013)“…In contrast to other B cell lymphomas, Hodgkin and Reed-Sternberg (HRS) cells, the malignant cells of classical Hodgkin lymphoma (cHL), have mainly lost their…”
Get full text
Journal Article -
15
FOXO1 downregulation contributes to the oncogenic program of primary mediastinal B-cell lymphoma
Published in Oncotarget (30-07-2014)“…Recently we have shown that the transcription factor FOXO1, highly expressed in B cells, is downregulated in classical Hodgkin lymphoma (cHL). As primary…”
Get full text
Journal Article