Search Results - "Xie, Leiming"
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Bioengineered bacterial outer membrane vesicles encapsulated Polybia-mastoparan I fusion peptide as a promising nanoplatform for bladder cancer immune-modulatory chemotherapy
Published in Frontiers in immunology (14-03-2023)“…Nanosized bacterial outer membrane vesicles (OMVs) secreted by Gram-negative bacteria have emerged as a novel antitumor nanomedicine reagent due to their…”
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Mitochondrial Trafficking and Processing of Telomerase RNA TERC
Published in Cell reports (Cambridge) (04-09-2018)“…Mitochondrial dysfunctions play major roles in many diseases. However, how mitochondrial stresses are relayed to downstream responses remains unclear. Here we…”
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In situ editing of tumour cell membranes induces aggregation and capture of PD-L1 membrane proteins for enhanced cancer immunotherapy
Published in Nature communications (09-11-2024)“…Immune checkpoint blockade (ICB) therapy has emerged as a new therapeutic paradigm for a variety of advanced cancers, but wide clinical application is hindered…”
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Mammalian mitochondrial RNAs are degraded in the mitochondrial intermembrane space by RNASET2
Published in Protein & cell (01-10-2017)“…Mammalian mitochondrial genome encodes a small set of tRNAs, rRNAs, and mRNAs. The RNA synthesis process has been well characterized. How the RNAs are…”
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Mitochondrion-processed TERC regulates senescence without affecting telomerase activities
Published in Protein & cell (01-09-2019)“…Mitochondrial dysfunctions play major roles in ageing. How mitochondrial stresses invoke downstream responses and how speci city of the signaling is achieved,…”
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Mitotic Implantation of the Transcription Factor Prospero via Phase Separation Drives Terminal Neuronal Differentiation
Published in Developmental cell (10-02-2020)“…Compacted heterochromatin blocks are prevalent in differentiated cells and present a barrier to cellular reprogramming. It remains obscure how heterochromatin…”
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Magnetic‐Powered Janus Cell Robots Loaded with Oncolytic Adenovirus for Active and Targeted Virotherapy of Bladder Cancer
Published in Advanced materials (Weinheim) (01-07-2022)“…A unique robotic medical platform is designed by utilizing cell robots as the active “Trojan horse” of oncolytic adenovirus (OA), capable of tumor‐selective…”
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Swarm Autonomy: From Agent Functionalization to Machine Intelligence
Published in Advanced materials (Weinheim) (02-05-2024)“…Swarm behaviors are common in nature, where individual organisms collaborate via perception, communication, and adaptation. Emulating these dynamics, large…”
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Engineered Microrobots for Targeted Delivery of Bacterial Outer Membrane Vesicles (OMV) in Thrombus Therapy
Published in Small (Weinheim an der Bergstrasse, Germany) (01-10-2024)“…In the realm of thrombosis treatment, bioengineered outer membrane vesicles (OMVs) offer a novel and promising approach, as they have rich content of…”
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Magnetically Powered Immunogenic Macrophage Microrobots for Targeted Multimodal Cancer Therapy
Published in Small (Weinheim an der Bergstrasse, Germany) (01-10-2023)“…Motile microrobots open a new realm for disease treatment. However, the concerns of possible immune elimination, targeted capability and limited therapeutic…”
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Phase-separated condensate-aided enrichment of biomolecular interactions for high-throughput drug screening in test tubes
Published in The Journal of biological chemistry (14-08-2020)“…Modification-dependent and -independent biomolecular interactions, including protein–protein, protein–DNA/RNA, protein–sugar, and protein–lipid interactions,…”
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Magnetically Powered Immunogenic Macrophage Microrobots for Targeted Multimodal Cancer Therapy (Small 42/2023)
Published in Small (Weinheim an der Bergstrasse, Germany) (01-10-2023)“…Targeted Multimodal Cancer TherapiesThe immunogenic cell‐based microrobots capable of multimodal cancer therapy are constructed by loading bioengineered…”
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Evolutional heterochromatin condensation delineates chromocenter formation and retrotransposon silencing in plants
Published in Nature plants (01-08-2024)“…Heterochromatic condensates (chromocenters) are critical for maintaining the silencing of heterochromatin. It is therefore puzzling that the presence of…”
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Protein adsorption enhanced radio-frequency heating of silica nanoparticles
Published in Applied physics letters (22-07-2013)“…Measurements of specific-absorption-rate (SAR) of silica 30, 50, and 100 nm nanoparticles (NP) suspended in water were carried out at 30 MHz in 7 kV/m…”
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A method to measure specific absorption rate of nanoparticles in colloidal suspension using different configurations of radio-frequency fields
Published in Applied physics letters (20-08-2012)“…We report a method for characterization of the efficiency of radio-frequency (rf) heating of nanoparticles (NPs) suspended in an aqueous medium. Measurements…”
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Use of the radiofrequency-intermodulation distortion technique to investigate intrinsic nonlinearity at the electrode-electrolyte interface
Published in Applied physics letters (06-02-2012)“…We report on investigations of nonlinear radiofrequency responses of electrolytes with Na + and Cl − ions placed within gold electrodes of a capacitor. The…”
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Microwave properties of single-walled carbon nanotubes films below percolation threshold
Published in Applied physics letters (08-06-2009)“…A film residue obtained by evaporating surfactant-stabilized single-walled carbon nanotube (SWNT) suspension was characterized at 12 GHz using a…”
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The mechanism of copper oxide segregations in Y-Ba-Cu-O/YSZ thin films
Published in Applied Physics A Solids and Surfaces (01-02-1990)Get full text
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Preparation of high J sub(c) YBa sub(2)Cu sub(3)O sub(7- delta ) superconducting thin films by ion beam sputtering deposition
Published in Applied physics. A, Materials science & processing (01-01-1991)“…Preparation of high T sub(c) and high J sub(c) YBa sub(3)Cu sub(3)O sub(7- delta ) superconducting thin films by ion beam sputtering deposition is reported…”
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Preparation of high J c YBa2Cu3O7?? superconducting thin films by ion beam sputtering deposition
Published in Applied Physics A Solids and Surfaces (01-03-1991)Get full text
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