Search Results - "Xie, Jiansheng"
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Roles of PFKFB3 in cancer
Published in Signal transduction and targeted therapy (24-11-2017)“…The understanding of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFK-2/FBPase 3, PFKFB3) has advanced considerably since its initial identification…”
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2
Optogenetic engineering to probe the molecular choreography of STIM1-mediated cell signaling
Published in Nature communications (25-02-2020)“…Genetically encoded photoswitches have enabled spatial and temporal control of cellular events to achieve tailored functions in living cells, but their…”
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3
Biochemical issues in estimation of cytosolic free NAD/NADH ratio
Published in PloS one (03-05-2012)“…Cytosolic free NAD/NADH ratio is fundamentally important in maintaining cellular redox homeostasis but current techniques cannot distinguish between…”
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4
The roles of transmembrane family proteins in the regulation of store-operated Ca2+ entry
Published in Cellular and molecular life sciences : CMLS (01-02-2022)“…Store-operated Ca 2+ entry (SOCE) is a major pathway for calcium signaling, which regulates almost every biological process, involving cell proliferation,…”
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Beyond Warburg effect – dual metabolic nature of cancer cells
Published in Scientific reports (13-05-2014)“…Warburg effect is a dominant phenotype of most cancer cells. Here we show that this phenotype depends on its environment. When cancer cells are under regular…”
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Range-Renewal Processes: SLLNs and Power Laws
Published in Chinese annals of mathematics. Serie B (2022)“…Given n samples (viewed as an n -tuple) of a γ -regular discrete distribution π , in this article the authors concern with the weighted and unweighted graphs…”
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7
TRIM59 promotes breast cancer motility by suppressing p62-selective autophagic degradation of PDCD10
Published in PLoS biology (08-11-2018)“…Cancer cells adopt various modes of migration during metastasis. How the ubiquitination machinery contributes to cancer cell motility remains underexplored…”
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Development of Store-Operated Calcium Entry-Targeted Compounds in Cancer
Published in Frontiers in pharmacology (28-05-2021)“…Store-operated Ca 2+ entry (SOCE) is the major pathway of Ca 2+ entry in mammalian cells, and regulates a variety of cellular functions including…”
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Compound heterozygous variants in MYH11 underlie autosomal recessive megacystis-microcolon-intestinal hypoperistalsis syndrome in a Chinese family
Published in Journal of human genetics (01-11-2019)“…Megacystis-microcolon-intestinal-hypoperistalsis syndrome (MMIHS) is a rare and severe disorder characterized by functional obstruction in the urinary and…”
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10
Central role of lactic acidosis in cancer cell resistance to glucose deprivation-induced cell death
Published in The Journal of pathology (01-06-2012)“…Solid tumours are dependent on glucose, but are generally glucose‐deprived due to poor vascularization. Nevertheless, cancer cells can generally survive…”
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TRIM59 deficiency promotes M1 macrophage activation and inhibits colorectal cancer through the STAT1 signaling pathway
Published in Scientific reports (12-07-2024)“…Tumor-associated macrophages play a crucial role in the tumor microenvironment. Tripartite motif 59 (TRIM59), a member of the tripartite motif (TRIM) family,…”
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Screening, prenatal diagnosis, and prenatal decision for sex chromosome aneuploidy
Published in Expert review of molecular diagnostics (03-06-2019)“…: To assess the performance of non-invasive prenatal testing (NIPT) in screening sex chromosome aneuploidy (SCA), and explore prenatal decision-making in NIPT…”
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13
Cyclosporine A sensitizes human non-small cell lung cancer cells to gefitinib through inhibition of STAT3
Published in Cancer letters (28-08-2016)“…Highlights • CsA significantly augments the anti-cancer effect of gefitinib in NSCLC cells. • CsA promotes gefitinib-induced apoptosis through inhibition of…”
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14
miR-26a attenuates colitis and colitis-associated cancer by targeting the multiple intestinal inflammatory pathways
Published in Molecular therapy. Nucleic acids (04-06-2021)“…Patients with inflammatory bowel disease are at increased risk for colitis-associated colorectal cancer (CAC). Therefore, controlling intestinal inflammation…”
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15
Asymptotic entropy of the ranges of random walks on discrete groups
Published in Science China. Mathematics (01-06-2020)“…Inspired by Benjamini et al. (2010) and Windisch (2010), we consider the entropy of the random walk ranges R n formed by the first n steps of a random walk S…”
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16
Necrostatin-1 reverts shikonin-induced necroptosis to apoptosis
Published in Apoptosis (London) (01-05-2009)“…Degterev et al. previously demonstrated that death receptor mediated apoptosis could be diverted to necroptosis when apoptosis signaling was blocked,…”
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Circular RNA hsa_circ_0081343 promotes trophoblast cell migration and invasion and inhibits trophoblast apoptosis by regulating miR-210-5p/DLX3 axis
Published in Reproductive biology and endocrinology (09-08-2021)“…Various circular RNAs (circRNAs) are dysregulated in the placenta of fetal growth restriction (FGR) fetuses, but their roles and regulatory mechanisms have not…”
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Anticancer agent shikonin is an incompetent inducer of cancer drug resistance
Published in PloS one (03-01-2013)“…Cancer drug resistance is a major obstacle for the success of chemotherapy. Since most clinical anticancer drugs could induce drug resistance, it is desired to…”
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The role of autophagy in colitis-associated colorectal cancer
Published in Signal transduction and targeted therapy (30-11-2018)“…Autophagy is an evolutionarily conserved catabolic process that eliminates harmful components through lysosomal degradation. In addition to its role in…”
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An ultralow dose of the NADPH oxidase inhibitor diphenyleneiodonium (DPI) is an economical and effective therapeutic agent for the treatment of colitis-associated colorectal cancer
Published in Theranostics (01-01-2020)“…Long-term inflammatory stimulation is considered one of the most important causes of colorectal cancer. Diphenyleneiodonium (DPI), an NADPH oxidase inhibitor,…”
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