Search Results - "Xiaoling DU"
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Glycolysis-Stimulated Esrrb Lactylation Promotes the Self-Renewal and Extraembryonic Endoderm Stem Cell Differentiation of Embryonic Stem Cells
Published in International journal of molecular sciences (01-03-2024)“…Embryonic stem cells (ESCs) favor glycolysis over oxidative phosphorylation for energy production, and glycolytic metabolism is critical for pluripotency…”
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Carbon-Based Nanomaterials in Sensors for Food Safety
Published in Nanomaterials (Basel, Switzerland) (01-09-2019)“…Food safety is one of the most important and widespread research topics worldwide. The development of relevant analytical methods or devices for detection of…”
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The genetic basis for inactivation of Wnt pathway in human osteosarcoma
Published in BMC cancer (18-06-2014)“…Osteosarcoma is a highly genetically unstable tumor with poor prognosis. We performed microarray-based comparative genomic hybridization (aCGH), transcriptome…”
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Clinical characteristics and antimicrobial therapy of healthcare-associated carbapenem-non-susceptible gram-negative bacterial meningitis: a 16-year retrospective cohort study
Published in BMC infectious diseases (02-04-2024)“…Healthcare-associated Gram-negative bacterial meningitis is a substantial clinical issue with poor outcomes, especially for neurosurgical patients. Here, we…”
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Advances in targeted therapy for unresectable melanoma: New drugs and combinations
Published in Cancer letters (01-04-2015)“…Highlights • This article is to overview the recent progress of targeted therapies for unresectable melanoma. • Targeted therapy has emerged and achieved great…”
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Lactylation of Hdac1 regulated by Ldh prevents the pluripotent-to-2C state conversion
Published in Stem cell research & therapy (13-11-2024)“…Cellular metabolism regulates the pluripotency of embryonic stem cells (ESCs). Yet, how metabolism regulates the transition among different pluripotent states…”
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Btbd8 deficiency reduces susceptibility to colitis by enhancing intestinal barrier function and suppressing inflammation
Published in Frontiers in immunology (2024)“…has been identified as a susceptible gene for inflammatory bowel diseases (IBD). However, the function of in normal development and IBD pathogenesis remains…”
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The ERα-NRF2 signalling axis promotes bicalutamide resistance in prostate cancer
Published in Cell communication and signaling (14-11-2022)“…Bicalutamide is a nonsteroidal antiandrogen widely used as a first-line clinical treatment for advanced prostate cancer (PCa). Although patients initially show…”
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The Essential Network (TEN): consulting stakeholders and experts to better understand implementation of a blended care mental health support services for Australian health professionals
Published in Australian journal of psychology (31-12-2024)“…Objective The Essential Network (TEN) is a blended care mental health support service for Australian health professionals. We conducted a series of…”
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CYP1B1-catalyzed 4-OHE2 promotes the castration resistance of prostate cancer stem cells by estrogen receptor α-mediated IL6 activation
Published in Cell communication and signaling (15-03-2022)“…Resistance to androgen deprivation therapy remains a major challenge for the clinical treatment of patients with castration-resistant prostate cancer (CRPC)…”
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A phase III, multicenter, double-blind, randomized clinical trial to evaluate the efficacy and safety of ceftolozane/tazobactam plus metronidazole versus meropenem in Chinese participants with complicated intra-abdominal infections
Published in International journal of infectious diseases (01-10-2022)“…•Phase III study of ceftolozane/tazobactam (C/T) plus metronidazole for complicated intra-abdominal infection in China.•C/T plus metronidazole was noninferior…”
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Clinical characteristics and prognostic indicators for metastatic melanoma: data from 446 patients in north China
Published in Tumor biology (01-08-2016)“…Melanoma is an extremely rare tumor in Asia. This retrospective study aimed to identify the clinical characteristics and prognostic factors of metastatic…”
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Mesenchymal to epithelial transition in sarcomas
Published in European journal of cancer (1990) (01-02-2014)“…Abstract Mesenchymal to epithelial transition (MET) in carcinomas has been proposed to promote the growth of epithelial tumour cells at distant sites during…”
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The HeyL-Aromatase Axis Promotes Cancer Stem Cell Properties by Endogenous Estrogen-Induced Autophagy in Castration-Resistant Prostate Cancer
Published in Frontiers in oncology (12-01-2022)“…Treatment of patients with castration-resistant prostate cancer (CRPC) remains a major clinical challenge. We previously showed that estrogenic effects…”
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Estrogen receptor α-NOTCH1 axis enhances basal stem-like cells and epithelial-mesenchymal transition phenotypes in prostate cancer
Published in Cell communication and signaling (23-05-2019)“…Prostate cancer (PCa) is the second leading cause of mortality and a leading cause of malignant tumors in males. Prostate cancer stem cells (PCSCs) are likely…”
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Genetic aberrations in soft tissue leiomyosarcoma
Published in Cancer letters (08-03-2009)“…Abstract Leiomyosarcoma is a malignant mesenchymal tumor composed of cells showing smooth muscle differentiation. This tumor usually occurs in middle-aged or…”
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Homozygous Loss of Septin12 , but not its Haploinsufficiency, Leads to Male Infertility and Fertilization Failure
Published in Frontiers in cell and developmental biology (25-04-2022)“…The gene has been associated with male infertility. Male chimera mice were infertile, supporting the prevailing view that haploinsufficiency causes male…”
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A diagnostic study of freezing rain over Guizhou, China, in January 2011
Published in Quarterly journal of the Royal Meteorological Society (01-07-2012)“…In early January 2011, southern China experienced another severe wintertime storm as in the winter of 2008. The storm consisted of a narrow east‐west‐oriented…”
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Estrogens Promote Invasion of Prostate Cancer Cells in a Paracrine Manner through Up-Regulation of Matrix Metalloproteinase 2 in Prostatic Stromal Cells
Published in Endocrinology (Philadelphia) (01-03-2011)“…We discuss the effect of estrogens on prostate cancer invasion, a novel mechanism of prostate cancer stroma-epithelium interaction. Accumulating evidence…”
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