Search Results - "Xiaocheng Li-Sucholeiki"
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Performance characteristics of a polymerase chain reaction-based assay for the detection of EGFR mutations in plasma cell-free DNA from patients with non-small cell lung cancer using cell-free DNA collection tubes
Published in PloS one (09-04-2024)“…Survival rates in non-small cell lung cancer (NSCLC) are low. Detection of circulating tumor DNA in liquid biopsy (plasma) is increasingly used to identify…”
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Tissue and Plasma EGFR Mutation Analysis in the FLAURA Trial: Osimertinib versus Comparator EGFR Tyrosine Kinase Inhibitor as First-Line Treatment in Patients with EGFR-Mutated Advanced Non-Small Cell Lung Cancer
Published in Clinical cancer research (15-11-2019)“…To assess the utility of the EGFR Mutation Test, with tissue and plasma, for first-line osimertinib therapy for patients with -mutated ( m; Ex19del and/or…”
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Biomarker-Directed Phase II Platform Study in Patients With EGFR Sensitizing Mutation-Positive Advanced/Metastatic Non-Small Cell Lung Cancer Whose Disease Has Progressed on First-Line Osimertinib Therapy (ORCHARD)
Published in Clinical lung cancer (01-11-2021)“…Osimertinib, a third-generation, irreversible, epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), selectively inhibits both EGFR-TKI…”
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SAVANNAH: A Phase II trial of osimertinib plus savolitinib for patients (pts) with EGFR -mutant, MET -driven ( MET +), locally advanced or metastatic non-small cell lung cancer (NSCLC), following disease progression on osimertinib
Published in Journal of clinical oncology (20-05-2019)“…Abstract only TPS9119 Background: The toxicity profile of the third-generation EGFR-tyrosine kinase inhibitor (TKI) osimertinib makes it an attractive backbone…”
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