Search Results - "Xiao, Zhi‐Jie"

Small Extracellular Vesicle-Derived vWF Induces a Positive Feedback Loop between Tumor and Endothelial Cells to Promote Angiogenesis and Metastasis in Hepatocellular Carcinoma by Wong, Samuel Wan Ki, Tey, Sze Keong, Mao, Xiaowen, Fung, Hiu Ling, Xiao, Zhi-Jie, Wong, Danny Ka Ho, Mak, Lung-Yi, Yuen, Man-Fung, Ng, Irene Oi-Lin, Yun, Jing Ping, Gao, Yi, Yam, Judy Wai Ping

“…Hepatocellular carcinoma (HCC) is a hypervascular malignancy by which its growth and dissemination are largely driven by the modulation of tumor-derived small…”
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Targeting GSTP1 as Therapeutic Strategy against Lung Adenocarcinoma Stemness and Resistance to Tyrosine Kinase Inhibitors by Wang, Si‐Qi, Chen, Jun‐Jiang, Jiang, Yuchen, Lei, Zi‐Ning, Ruan, Ye Chun, Pan, Yihang, Yam, Judy Wai Ping, Wong, Maria Pik, Xiao, Zhi‐Jie

“…Glutathione S‐transferase pi (GSTP1), a phase II detoxification enzyme, is known to be overexpressed and mediates chemotherapeutic resistance in lung cancer…”
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NFATc2 enhances tumor-initiating phenotypes through the NFATc2/SOX2/ALDH axis in lung adenocarcinoma by Xiao, Zhi-Jie, Liu, Jing, Wang, Si-Qi, Zhu, Yun, Gao, Xu-Yuan, Tin, Vicky Pui-Chi, Qin, Jing, Wang, Jun-Wen, Wong, Maria Pik

“…Tumor-initiating cells (TIC) are dynamic cancer cell subsets that display enhanced tumor functions and resilience to treatment but the mechanism of TIC…”
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The Benefits and Risks of Statin Therapy in Ischemic Stroke: A Review of the Literature by Zhao, Wang, Xiao, Zhi-Jie, Zhao, Shui-Ping

“…Statins are effective cholesterol-lowering drugs for reducing the risks of mortality and morbidity of cardiovascular diseases. Increasing evidence has shown…”
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The Dual Role of the NFATc2/galectin‐9 Axis in Modulating Tumor‐Initiating Cell Phenotypes and Immune Suppression in Lung Adenocarcinoma by Xiao, Zhi‐Jie, Wang, Si‐Qi, Chen, Jun‐Jiang, Li, Yun, Jiang, Yuchen, Tin, Vicky Pui‐Chi, Liu, Jia, Hu, Huiyi, Wong, Maria Pik, Pan, Yihang, Yam, Judy Wai Ping

“…Tumor‐initiating cells (TICs) resilience and an immunosuppressive microenvironment are aggressive oncogenic phenotypes that contribute to unsatisfactory…”
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Nilotinib potentiates anticancer drug sensitivity in murine ABCB1-, ABCG2-, and ABCC10-multidrug resistance xenograft models by Tiwari, Amit K, Sodani, Kamlesh, Dai, Chun-ling, Abuznait, Alaa H, Singh, Satyakam, Xiao, Zhi-Jie, Patel, Atish, Talele, Tanaji T, Fu, Liwu, Kaddoumi, Amal, Gallo, James M, Chen, Zhe-Sheng

“…Highlights ► Nilotinib compared to panel of tyrosine kinase inhibitors most potently reverse ABCB1, ABCG2 and ABCC10 transporters mediated drug resistance. ►…”
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NHE7 upregulation potentiates the uptake of small extracellular vesicles by enhancing maturation of macropinosomes in hepatocellular carcinoma by Yao, Yue, Xu, Yi, Yu, Liang, Xue, Ting‐Mao, Xiao, Zhi‐Jie, Tin, Pui‐Chi, Fung, Hiu‐Ling, Ma, Hoi‐Tang, Yun, Jing‐Ping, Yam, Judy Wai Ping

“…Background Small extracellular vesicles (sEVs) mediate intercellular communication that contributes to hepatocellular carcinoma (HCC) progression via…”
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MRP4 sustains Wnt/β-catenin signaling for pregnancy, endometriosis and endometrial cancer by Chen, Jun-Jiang, Xiao, Zhi-Jie, Meng, Xiaojing, Wang, Yan, Yu, Mei Kuen, Huang, Wen Qing, Sun, Xiao, Chen, Hao, Duan, Yong-Gang, Jiang, Xiaohua, Wong, Maria Pik, Chan, Hsiao Chang, Zou, Fei, Ruan, Ye Chun

“…: Abnormal Wnt/β-catenin signaling in the endometrium can lead to both embryo implantation failure and severe pathogenic changes of the endometrium such as…”
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CAMK2A supported tumor initiating cells of lung adenocarcinoma by upregulating SOX2 through EZH2 phosphorylation by Wang, Si-Qi, Liu, Jing, Qin, Jing, Zhu, Yun, Tin, Vicky Pui-Chi, Yam, Judy Wai Ping, Wong, Maria Pik, Xiao, Zhi-Jie

“…Tumor initiating cells (TIC) of lung cancer are mainly induced by stress-related plasticity. Calcium/Calmodulin dependent protein kinase II alpha (CAMK2A) is a…”
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GW583340 and GW2974, human EGFR and HER-2 inhibitors, reverse ABCG2- and ABCB1-mediated drug resistance by Sodani, Kamlesh, Tiwari, Amit K., Singh, Satyakam, Patel, Atish, Xiao, Zhi-Jie, Chen, Jun-Jiang, Sun, Yue-Li, Talele, Tanaji T., Chen, Zhe-Sheng

“…The overexpression of ATP binding cassette (ABC) transporters often leads to the development of multidrug resistance (MDR) and results in a suboptimal response…”
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Psychosis secondary to recurrent spinal meningioma by Xiao, Min-Jia, Fang, Fang, Zhan, Ya-Jing, Xiao, Zhi-Jie, Lan, Zi-Wei

“…Based on this case, spinal meningioma should also be included as an etiology of anti-NMDAR encephalitis. [...]central nervous system neoplasms should be taken…”
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PDE5 inhibitors, sildenafil and vardenafil, reverse multidrug resistance by inhibiting the efflux function of multidrug resistance protein 7 (ATP‐binding Cassette C10) transporter by Chen, Jun‐Jiang, Sun, Yue‐Li, Tiwari, Amit K., Xiao, Zhi‐Jie, Sodani, Kamlesh, Yang, Dong‐Hua, Vispute, Saraubh G., Jiang, Wen‐Qi, Chen, Si‐Dong, Chen, Zhe‐Sheng

“…Phosphodiesterase type 5 (PDE5) inhibitors are widely used in the treatment of male erectile dysfunction and pulmonary hypertension. Recently, several groups…”
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bba, a synthetic derivative of 23-hydroxybutulinic acid, reverses multidrug resistance by inhibiting the efflux activity of MRP7 (ABCC10) by Chen, Jun-Jiang, Patel, Atish, Sodani, Kamlesh, Xiao, Zhi-Jie, Tiwari, Amit K, Zhang, Dong-Mei, Li, Ying-Jie, Yang, Dong-Hua, Ye, Wen-Cai, Chen, Si-Dong, Chen, Zhe-Sheng

“…Natural products are frequently used for adjuvant chemotherapy in cancer treatment. 23-O-(1,4'-bipiperidine-1-carbonyl) betulinic acid (BBA) is a synthetic…”
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Blood-Brain Barrier: More Contributor to Disruption of Central Nervous System Homeostasis Than Victim in Neurological Disorders by Xiao, Minjia, Xiao, Zhi Jie, Yang, Binbin, Lan, Ziwei, Fang, Fang

“…The blood-brain barrier (BBB) is a dynamic but solid shield in the cerebral microvascular system. It plays a pivotal role in maintaining central nervous system…”
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BBA, a Derivative of 23-Hydroxybetulinic Acid, Potently Reverses ABCB1-Mediated Drug Resistance in Vitro and in Vivo by Zhang, Dong-Mei, Shu, Chang, Chen, Jun-Jiang, Sodani, Kamlesh, Wang, Jiao, Bhatnagar, Jaya, Lan, Ping, Ruan, Zhi-Xiong, Xiao, Zhi-Jie, Ambudkar, Suresh V, Chen, Wei-Min, Chen, Zhe-Sheng, Ye, Wen-Cai

“…23-O-(1,4′-Bipiperidine-1-carbonyl)betulinic acid (BBA), a synthetic derivative of 23-hydroxybetulinic acid (23-HBA), shows a reversal effect on multidrug…”
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Ameliorative effects of physcion 8-O-β-glucopyranoside isolated from Polygonum cuspidatum on learning and memory in dementia rats induced by Aβ1-40 by Xu, Nian-Gui, Xiao, Zhi-Jie, Zou, Ting, Huang, Zhi-Ling

“…Polygonum cuspidatum Sieb. Et Zucc. (Polygonaceae) has been traditionally used in folk medicine to treat various diseases. This study investigates the…”
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Identify practice gaps in medication education through surveys to patients and physicians by Yi, Zhan-Miao, Zhi, Xiao-Jie, Yang, Ling, Sun, Shu-Sen, Zhang, Zhuo, Sun, Zhi-Ming, Zhai, Suo-Di

“…Effective communication and education formats between health care providers and patients about medication use are associated with patients' satisfaction,…”
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Effects of Matrix Proteins on the Expression of Matrix Metalloproteinase-2, -9, and -14 and Tissue Inhibitors of Metalloproteinases in Human Cytotrophoblast Cells During the First Trimester by PING XU, WANG, Yan-Ling, PIAO, Yun-Shang, BAI, Su-Xia, XIAO, Zhi-Jie, JIA, Ya-Li, LUO, Shu-Yi, ZHUANG, Lin-Zhi

“…The activity of matrix metalloproteinases (MMPs) specifies the ability of the trophoblast cell to degrade extracellular matrix (ECM) substrates. Usually the…”
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The lipoprotein lipase Ser447Ter mutation and risk of stroke in the Chinese by Zhao, Shui-Ping, Tong, Qi-Guang, Xiao, Zhi-Jie, Cheng, Yan-Chun, Zhou, Hong-Nian, Nie, Shai

“…Background: Lipoprotein lipase (LPL) plays an important role in plasma lipoprotein metabolism. The Ser447Ter mutation of LPL may be associated with ischemic…”
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Expression of P450 aromatase and 17β-hydroxysteroid dehydrogenase type 1 at fetal–maternal interface during tubal pregnancy by Li, Yan, Qin, Li, Xiao, Zhi-Jie, Wang, Yan-Ling, Herva, Riitta, Leng, Jin-Hua, Lang, Jing-He, Isomaa, Veli, Piao, Yun-Shang

“…Steroidogenesis in the placenta has been studied widely, but little is known about steroid metabolism in ectopic pregnancy. Previous studies have indicated…”
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