Search Results - "Xiao, Z X"
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RSK1 SUMOylation is required for KSHV lytic replication
Published in PLoS pathogens (01-12-2021)“…RSK1, a downstream kinase of the MAPK pathway, has been shown to regulate multiple cellular processes and is essential for lytic replication of a variety of…”
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2
MDMX exerts its oncogenic activity via suppression of retinoblastoma protein
Published in Oncogene (29-10-2015)“…Inactivation of the retinoblastoma protein (RB) has a major role in the development of human malignancies. We have previously shown that MDM2, an ubiquitin E3…”
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3
The SUMO E3 ligase activity of ORF45 determines KSHV lytic replication
Published in PLoS pathogens (28-04-2022)“…RSK1, an essential cellular kinase for Kaposi's sarcoma-associated herpesvirus (KSHV) replication, is highly phosphorylated and SUMOylated during KSHV lytic…”
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4
ΔNp63α regulates Erk signaling via MKP3 to inhibit cancer metastasis
Published in Oncogene (09-01-2014)“…Reduced expression of the p53 family member p63 has been suggested to play a causative role in cancer metastasis. Here, we show that ΔNp63α, the predominant…”
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5
Chemical composition analysis of seed oil from five wild almond species in China as potential edible oil resource for the future
Published in South African journal of botany (01-03-2019)“…The genetic resources of wild almond have not been paid enough attention for oil chemical components and uses. In the present study analyses concerning the…”
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KSHV-encoded ORF45 activates human NLRP1 inflammasome
Published in Nature immunology (01-06-2022)“…At steady state, the NOD-like receptor (NLR)-containing pyrin domain (PYD) (NLRP)1 inflammasome is maintained in an auto-inhibitory complex by dipeptidyl…”
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ORF3a-Mediated Incomplete Autophagy Facilitates Severe Acute Respiratory Syndrome Coronavirus-2 Replication
Published in Frontiers in cell and developmental biology (27-07-2021)“…Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative agent for the coronavirus disease 2019 (COVID-19) pandemic and there is an urgent…”
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8
Noncanonical inheritance of phenotypic information by protein amyloids
Published in Nature cell biology (01-10-2024)“…All known heritable phenotypic information in animals is transmitted by direct inheritance of nucleic acids, their covalent modifications or histone…”
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Patterns of Gene Expression in Cutaneous T-Cell Lymphoma: Systematic Review of Transcriptomic Studies in Mycosis Fungoides
Published in Cells (Basel, Switzerland) (06-06-2021)“…Mycosis fungoides (MF) is the most prevalent type of skin lymphoma. In its early stages, it has a favorable prognosis. However, in its late stages, it is…”
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10
Glial-modulating agents for the treatment of pain: protocol for a systematic review
Published in BMJ open (06-04-2022)“…IntroductionEvidence suggests a role for Central nervous system glia in pain transmission and in augmenting maladaptive opioid effects. Identification of drugs…”
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Retinoblastoma protein modulates gankyrin-MDM2 in regulation of p53 stability and chemosensitivity in cancer cells
Published in Oncogene (03-07-2008)“…MDM2 is a key ubiquitin E3 ligase for p53 and its activity is critically regulated by a set of modulators, including ARF, p300, YY1 and recently by gankyrin,…”
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The essential role of costimulatory molecules in systemic lupus erythematosus
Published in Lupus (01-04-2019)“…Systemic lupus erythematosus (SLE) is a chronic inflammatory disease with immune system disorder mediated through complex autoimmune pathways that involve…”
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13
p300/MDM2 Complexes Participate in MDM2-Mediated p53 Degradation
Published in Molecular cell (01-10-1998)“…Control of p53 turnover is critical to p53 function. E1A binding to p300/CBP translates into enhanced p53 stability, implying that these coactivator proteins…”
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ARF promotes accumulation of retinoblastoma protein through inhibition of MDM2
Published in Oncogene (12-07-2007)“…The INK4a/ARF locus, encoding two tumor suppressor proteins, p16(INK4a) and p14(ARF) (ARF), plays key roles in many cellular processes including cell…”
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Texture evolution and mechanical behaviour of irradiated face-centred cubic metals
Published in Proceedings of the Royal Society. A, Mathematical, physical, and engineering sciences (01-02-2018)“…A physically based theoretical model is proposed to investigate the mechanical behaviour and crystallographic texture evolution of irradiated face-centred…”
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Pin1 inhibits PP2A-mediated Rb dephosphorylation in regulation of cell cycle and S-phase DNA damage
Published in Cell death & disease (01-02-2015)“…Inactivation of the retinoblastoma protein (Rb) has a key role in tumorigenesis. It is well established that Rb function is largely regulated by a dynamic…”
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Pin1 modulates p63α protein stability in regulation of cell survival, proliferation and tumor formation
Published in Cell death & disease (01-12-2013)“…The homolog of p53 gene, p63, encodes multiple p63 protein isoforms. TAp63 proteins contain an N-terminal transactivation domain similar to that of p53 and…”
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ΔNp63α activates CD82 metastasis suppressor to inhibit cancer cell invasion
Published in Cell death & disease (05-06-2014)“…P63 is a p53 family member involved in multiple facets of biology, including embryonic development, cell proliferation, differentiation, survival, apoptosis,…”
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Gastric content and perioperative pulmonary aspiration in patients with diabetes mellitus: a scoping review
Published in British journal of anaesthesia : BJA (01-08-2021)“…Gastric emptying may be delayed in patients with diabetes mellitus (DM). However, the incidence of full stomach in fasting patients with DM and their risk of…”
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Mechanical properties for irradiated face-centred cubic nanocrystalline metals
Published in Proceedings of the Royal Society. A, Mathematical, physical, and engineering sciences (08-05-2015)“…In this paper, a self-consistent plasticity theory is proposed to model the mechanical behaviours of irradiated face-centred cubic nanocrystalline metals. At…”
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