Search Results - "Xiao, Tianhe"

Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies by Cao, Yunlong, Wang, Jing, Jian, Fanchong, Xiao, Tianhe, Song, Weiliang, Yisimayi, Ayijiang, Huang, Weijin, Li, Qianqian, Wang, Peng, An, Ran, Wang, Jing, Wang, Yao, Niu, Xiao, Yang, Sijie, Liang, Hui, Sun, Haiyan, Li, Tao, Yu, Yuanling, Cui, Qianqian, Liu, Shuo, Yang, Xiaodong, Du, Shuo, Zhang, Zhiying, Hao, Xiaohua, Shao, Fei, Jin, Ronghua, Wang, Xiangxi, Xiao, Junyu, Wang, Youchun, Xie, Xiaoliang Sunney

“…The SARS-CoV-2 B.1.1.529 (Omicron) variant contains 15 mutations of the receptor-binding domain (RBD). How Omicron evades RBD-targeted neutralizing antibodies…”
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Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines by Cao, Yunlong, Yisimayi, Ayijiang, Bai, Yali, Huang, Weijin, Li, Xiaofeng, Zhang, Zhiying, Yuan, Tianjiao, An, Ran, Wang, Jing, Xiao, Tianhe, Du, Shuo, Ma, Wenping, Song, Liyang, Li, Yongzheng, Li, Xiang, Song, Weiliang, Wu, Jiajing, Liu, Shuo, Li, Xuemei, Zhang, Yonghong, Su, Bin, Guo, Xianghua, Wei, Yangyang, Gao, Chuanping, Zhang, Nana, Zhang, Yifei, Dou, Yang, Xu, Xiaoyu, Shi, Rui, Lu, Bai, Jin, Ronghua, Ma, Yingmin, Qin, Chengfeng, Wang, Youchun, Feng, Yingmei, Xiao, Junyu, Xie, Xiaoliang Sunney

“…SARS-CoV-2 variants could induce immune escape by mutations on the receptor-binding domain (RBD) and N-terminal domain (NTD). Here we report the humoral immune…”
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BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection by Cao, Yunlong, Yisimayi, Ayijiang, Jian, Fanchong, Song, Weiliang, Xiao, Tianhe, Wang, Lei, Du, Shuo, Wang, Jing, Li, Qianqian, Chen, Xiaosu, Yu, Yuanling, Wang, Peng, Zhang, Zhiying, Liu, Pulan, An, Ran, Hao, Xiaohua, Wang, Yao, Wang, Jing, Feng, Rui, Sun, Haiyan, Zhao, Lijuan, Zhang, Wen, Zhao, Dong, Zheng, Jiang, Yu, Lingling, Li, Can, Zhang, Na, Wang, Rui, Niu, Xiao, Yang, Sijie, Song, Xuetao, Chai, Yangyang, Hu, Ye, Shi, Yansong, Zheng, Linlin, Li, Zhiqiang, Gu, Qingqing, Shao, Fei, Huang, Weijin, Jin, Ronghua, Shen, Zhongyang, Wang, Youchun, Wang, Xiangxi, Xiao, Junyu, Xie, Xiaoliang Sunney

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages BA.2.12.1, BA.4 and BA.5 exhibit higher transmissibility than the BA.2 lineage…”
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Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting by Yisimayi, Ayijiang, Song, Weiliang, Wang, Jing, Jian, Fanchong, Yu, Yuanling, Chen, Xiaosu, Xu, Yanli, Yang, Sijie, Niu, Xiao, Xiao, Tianhe, Wang, Jing, Zhao, Lijuan, Sun, Haiyan, An, Ran, Zhang, Na, Wang, Yao, Wang, Peng, Yu, Lingling, Lv, Zhe, Gu, Qingqing, Shao, Fei, Jin, Ronghua, Shen, Zhongyang, Xie, Xiaoliang Sunney, Wang, Youchun, Cao, Yunlong

“…The continuing emergence of SARS-CoV-2 variants highlights the need to update COVID-19 vaccine compositions. However, immune imprinting induced by vaccination…”
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Structures of SARS-CoV-2 B.1.351 neutralizing antibodies provide insights into cocktail design against concerning variants by Du, Shuo, Liu, Pulan, Zhang, Zhiying, Xiao, Tianhe, Yasimayi, Ayijiang, Huang, Weijin, Wang, Youchun, Cao, Yunlong, Xie, Xiaoliang Sunney, Xiao, Junyu

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CRISPR screening of porcine sgRNA library identifies host factors associated with Japanese encephalitis virus replication by Zhao, Changzhi, Liu, Hailong, Xiao, Tianhe, Wang, Zichang, Nie, Xiongwei, Li, Xinyun, Qian, Ping, Qin, Liuxing, Han, Xiaosong, Zhang, Jinfu, Ruan, Jinxue, Zhu, Mengjin, Miao, Yi-Liang, Zuo, Bo, Yang, Kui, Xie, Shengsong, Zhao, Shuhong

“…Japanese encephalitis virus (JEV) is a mosquito-borne zoonotic flavivirus that causes encephalitis and reproductive disorders in mammalian species. However,…”
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Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies by Cao, Yunlong, Wang, Jing, Jian, Fanchong, Xiao, Tianhe, Song, Weiliang, Yisimayi, Ayijiang, Huang, Weijin, Li, Qianqian, Wang, Peng, An, Ran, Wang, Yao, Niu, Xiao, Yang, Sijie, Liang, Hui, Sun, Haiyan, Li, Tao, Yu, Yuanling, Cui, Qianqian, Liu, Shuo, Yang, Xiaodong, Du, Shuo, Zhang, Zhiying, Hao, Xiaohua, Shao, Fei, Jin, Ronghua, Wang, Xiangxi, Xiao, Junyu, Wang, Youchun, Xie, Xiaoliang Sunney

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Omicron-specific ultra-potent SARS-CoV-2 neutralizing antibodies targeting the N1/N2 loop of Spike N-terminal domain by Niu, Xiao, Li, Zhiqiang, Wang, Jing, Jian, Fanchong, Yu, Yuanling, Song, Weiliang, Yisimayi, Ayijiang, Du, Shuo, Zhang, Zhiying, Wang, Qianran, Wang, Jing, An, Ran, Wang, Yao, Wang, Peng, Sun, Haiyan, Yu, Lingling, Yang, Sijie, Xiao, Tianhe, Gu, Qingqing, Shao, Fei, Wang, Youchun, Xiao, Junyu, Cao, Yunlong

“…A multitude of functional mutations continue to emerge on the N-terminal domain (NTD) of the spike protein in SARS-CoV-2 Omicron subvariants. Understanding the…”
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Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution by Cao, Yunlong, Jian, Fanchong, Wang, Jing, Yu, Yuanling, Song, Weiliang, Yisimayi, Ayijiang, Wang, Jing, An, Ran, Chen, Xiaosu, Zhang, Na, Wang, Yao, Wang, Peng, Zhao, Lijuan, Sun, Haiyan, Yu, Lingling, Yang, Sijie, Niu, Xiao, Xiao, Tianhe, Gu, Qingqing, Shao, Fei, Hao, Xiaohua, Xu, Yanli, Jin, Ronghua, Shen, Zhongyang, Wang, Youchun, Xie, Xiaoliang Sunney

“…Continuous evolution of Omicron has led to a rapid and simultaneous emergence of numerous variants that display growth advantages over BA.5 (ref. 1 ). Despite…”
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Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75 by Cao, Yunlong, Song, Weiliang, Wang, Lei, Liu, Pan, Yue, Can, Jian, Fanchong, Yu, Yuanling, Yisimayi, Ayijiang, Wang, Peng, Wang, Yao, Zhu, Qianhui, Deng, Jie, Fu, Wangjun, Yu, Lingling, Zhang, Na, Wang, Jing, Xiao, Tianhe, An, Ran, Wang, Jing, Liu, Lu, Yang, Sijie, Niu, Xiao, Gu, Qingqing, Shao, Fei, Hao, Xiaohua, Meng, Bo, Gupta, Ravindra Kumar, Jin, Ronghua, Wang, Youchun, Xie, Xiaoliang Sunney, Wang, Xiangxi

“…Recently emerged SARS-CoV-2 Omicron subvariant, BA.2.75, displayed a growth advantage over circulating BA.2.38, BA.2.76, and BA.5 in India. However, the…”
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Antigenicity and infectivity characterisation of SARS-CoV-2 BA.2.86 by Yang, Sijie, Yu, Yuanling, Jian, Fanchong, Song, Weiliang, Yisimayi, Ayijiang, Chen, Xiaosu, Xu, Yanli, Wang, Peng, Wang, Jing, Yu, Lingling, Niu, Xiao, Wang, Jing, Xiao, Tianhe, An, Ran, Wang, Yao, Gu, Qingqing, Shao, Fei, Jin, Ronghua, Shen, Zhongyang, Wang, Youchun, Cao, Yunlong

“…By Sept 8, 2023, 95 sequences were detected, of which their early sequences originated from multiple countries, had no epidemiological relevance, and were…”
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Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding by Jian, Fanchong, Feng, Leilei, Yang, Sijie, Yu, Yuanling, Wang, Lei, Song, Weiliang, Yisimayi, Ayijiang, Chen, Xiaosu, Xu, Yanli, Wang, Peng, Yu, Lingling, Wang, Jing, Liu, Lu, Niu, Xiao, Wang, Jing, Xiao, Tianhe, An, Ran, Wang, Yao, Gu, Qingqing, Shao, Fei, Jin, Ronghua, Shen, Zhongyang, Wang, Youchun, Wang, Xiangxi, Cao, Yunlong

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) XBB lineages have achieved dominance worldwide and keep on evolving. Convergent evolution of XBB…”
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Rational identification of potent and broad sarbecovirus-neutralizing antibody cocktails from SARS convalescents by Cao, Yunlong, Jian, Fanchong, Zhang, Zhiying, Yisimayi, Ayijiang, Hao, Xiaohua, Bao, Linlin, Yuan, Fei, Yu, Yuanling, Du, Shuo, Wang, Jing, Xiao, Tianhe, Song, Weiliang, Zhang, Ying, Liu, Pulan, An, Ran, Wang, Peng, Wang, Yao, Yang, Sijie, Niu, Xiao, Zhang, Yuhang, Gu, Qingqing, Shao, Fei, Hu, Yaling, Yin, Weidong, Zheng, Aihua, Wang, Youchun, Qin, Chuan, Jin, Ronghua, Xiao, Junyu, Xie, Xiaoliang Sunney

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages have escaped most receptor-binding domain (RBD)-targeting therapeutic…”
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Isolation and characterization of a Sabin 3/Sabin 1 recombinant vaccine-derived poliovirus from a child with severe combined immunodeficiency by Xiao, Tianhe, Leng, Hongying, Zhang, Qian, Chen, Qiang, Guo, Hongxiong, Qi, Yuhua

“…•A long-term secreted Sabin 3/Sabin 1 recombinant vaccine-derived poliovirus from a child with severe combined immunodeficiency.•A modified NGS platform to…”
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Evolving antibody response to SARS-CoV-2 antigenic shift from XBB to JN.1 by Jian, Fanchong, Wang, Jing, Yisimayi, Ayijiang, Song, Weiliang, Xu, Yanli, Chen, Xiaosu, Niu, Xiao, Yang, Sijie, Yu, Yuanling, Wang, Peng, Sun, Haiyan, Yu, Lingling, Wang, Jing, Wang, Yao, An, Ran, Wang, Wenjing, Ma, Miaomiao, Xiao, Tianhe, Gu, Qingqing, Shao, Fei, Wang, Youchun, Shen, Zhongyang, Jin, Ronghua, Cao, Yunlong

“…The continuous evolution of SARS-CoV-2, particularly the emergence of BA.2.86/JN.1 lineage replacing XBB, necessitates re-evaluation of vaccine compositions…”
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Arming AAV9 with a Single-Chain Fragment Variable Antibody Against PD-1 for Systemic Glioblastoma Therapy by Maksoud, Semer, Schweiger, Markus W, Tabet, Elie I, Xiao, Tianhe, Hokayem, Joelle El, Zinter, Max, Carvalho, Litia A, Breyne, Koen, Noske, David P, Chiocca, Ennio Antonio, Tannous, Bakhos A

“…Glioblastoma (GBM) is a highly aggressive brain cancer with a low survival rate, prompting the exploration of novel therapeutic strategies. Immune checkpoint…”
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Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity by Liu, Pan, Yue, Can, Meng, Bo, Xiao, Tianhe, Yang, Sijie, Liu, Shuo, Jian, Fanchong, Zhu, Qianhui, Yu, Yuanling, Ren, Yanyan, Wang, Peng, Li, Yixin, Wang, Jinyue, Mao, Xin, Shao, Fei, Wang, Youchun, Gupta, Ravindra Kumar, Cao, Yunlong, Wang, Xiangxi

“…Selective pressures have given rise to a number of SARS-CoV-2 variants during the prolonged course of the COVID-19 pandemic. Recently evolved variants differ…”
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