Search Results - "Xiao, Feizhe"

A novel protein encoded by the circular form of the SHPRH gene suppresses glioma tumorigenesis by Zhang, Maolei, Huang, Nunu, Yang, Xuesong, Luo, Jingyan, Yan, Sheng, Xiao, Feizhe, Chen, Wenping, Gao, Xinya, Zhao, Kun, Zhou, Huangkai, Li, Ziqiang, Ming, Liu, Xie, Bo, Zhang, Nu

“…Circular RNAs (circRNAs) are recognized as functional non-coding transcripts in eukaryotic cells. Recent evidence has indicated that even though circRNAs are…”
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Circular RNA-encoded oncogenic E-cadherin variant promotes glioblastoma tumorigenicity through activation of EGFR–STAT3 signalling by Gao, Xinya, Xia, Xin, Li, Fanying, Zhang, Maolei, Zhou, Huangkai, Wu, Xujia, Zhong, Jian, Zhao, Zheng, Zhao, Kun, Liu, Dawei, Xiao, Feizhe, Xu, Qiang, Jiang, Tao, Li, Bo, Cheng, Shi-Yuan, Zhang, Nu

“…Activated EGFR signalling drives tumorigenicity in 50% of glioblastoma (GBM). However, EGFR-targeting therapy has proven ineffective in treating patients with…”
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A peptide encoded by circular form of LINC-PINT suppresses oncogenic transcriptional elongation in glioblastoma by Zhang, Maolei, Zhao, Kun, Xu, Xiaoping, Yang, Yibing, Yan, Sheng, Wei, Ping, Liu, Hui, Xu, Jianbo, Xiao, Feizhe, Zhou, Huangkai, Yang, Xuesong, Huang, Nunu, Liu, Jinglei, He, Kejun, Xie, Keping, Zhang, Gong, Huang, Suyun, Zhang, Nu

“…Circular RNAs (circRNAs) are a large class of transcripts in the mammalian genome. Although the translation of circRNAs was reported, additional coding…”
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A novel tumor suppressor protein encoded by circular AKT3 RNA inhibits glioblastoma tumorigenicity by competing with active phosphoinositide-dependent Kinase-1 by Xia, Xin, Li, Xixi, Li, Fanying, Wu, Xujia, Zhang, Maolei, Zhou, Huangkai, Huang, Nunu, Yang, Xuesong, Xiao, Feizhe, Liu, Dawei, Yang, Lixuan, Zhang, Nu

“…The RTK/PI3K/AKT pathway plays key roles in the development and progression of many cancers, including GBM. As a regulatory molecule and a potential drug…”
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A novel protein encoded by circular SMO RNA is essential for Hedgehog signaling activation and glioblastoma tumorigenicity by Wu, Xujia, Xiao, Songhua, Zhang, Maolei, Yang, Lixuan, Zhong, Jian, Li, Bo, Li, Fanying, Xia, Xin, Li, Xixi, Zhou, Huangkai, Liu, Dawei, Huang, Nunu, Yang, Xuesong, Xiao, Feizhe, Zhang, Nu

“…Aberrant activation of the Hedgehog pathway drives tumorigenesis of many cancers, including glioblastoma. However, the sensitization mechanism of the G…”
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Circular HER2 RNA positive triple negative breast cancer is sensitive to Pertuzumab by Li, Jie, Ma, Maoguang, Yang, Xuesong, Zhang, Maolei, Luo, Jingyan, Zhou, Huangkai, Huang, Nunu, Xiao, Feizhe, Lai, Bingquan, Lv, Weiming, Zhang, Nu

“…Abstract Background Triple negative breast cancer (TNBC) remains the most challenging breast cancer subtype so far. Specific therapeutic approaches have rarely…”
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Circular EZH2-encoded EZH2-92aa mediates immune evasion in glioblastoma via inhibition of surface NKG2D ligands by Zhong, Jian, Yang, Xuesong, Chen, Junju, He, Kejun, Gao, Xinya, Wu, Xujia, Zhang, Maolei, Zhou, Huangkai, Xiao, Feizhe, An, Lele, Wang, Xiuxing, Shi, Yu, Zhang, Nu

“…Glioblastoma (GBM) is a highly aggressive primary brain tumour and is resistant to nearly all available treatments, including natural killer (NK) cell…”
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Circular RNA encoded MET variant promotes glioblastoma tumorigenesis by Zhong, Jian, Wu, Xujia, Gao, Yixin, Chen, Junju, Zhang, Maolei, Zhou, Huangkai, Yang, Jia, Xiao, Feizhe, Yang, Xuesong, Huang, Nunu, Qi, Haoyue, Wang, Xiuxing, Bai, Fan, Shi, Yu, Zhang, Nu

“…Activated by its single ligand, hepatocyte growth factor (HGF), the receptor tyrosine kinase MET is pivotal in promoting glioblastoma (GBM) stem cell…”
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FoxM1 Inhibition Sensitizes Resistant Glioblastoma Cells to Temozolomide by Downregulating the Expression of DNA-Repair Gene Rad51 by Zhang, Nu, Wu, Xinjian, Yang, Lixuan, Xiao, Feizhe, Zhang, Heng, Zhou, Aidong, Huang, Zhengsong, Huang, Suyun

“…Recurrent glioblastoma multiforme (GBM) is characterized by resistance to radiotherapy and chemotherapy and a poor clinical prognosis. In this study, we…”
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Correction: A novel tumor suppressor protein encoded by circular AKT3 RNA inhibits glioblastoma tumorigenicity by competing with active phosphoinositide-dependent Kinase-1 by Xia, Xin, Li, Xixi, Li, Fanying, Wu, Xujia, Zhang, Maolei, Zhou, Huangkai, Huang, Nunu, Yang, Xuesong, Xiao, Feizhe, Liu, Dawei, Yang, Lixuan, Zhang, Nu

“…Mol Cancer 18, 131 (2019) https://doi.org/10.1186/s12943-019-1056-5 Following publication of the original article [1], errors were identified in the images…”
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Correction to: A novel tumor suppressor protein encoded by circular AKT3 RNA inhibits glioblastoma tumorigenicity by competing with active phosphoinositide-dependent Kinase-1 by Xia, Xin, Li, Xixi, Li, Fanying, Wu, Xujia, Zhang, Maolei, Zhou, Huangkai, Huang, Nunu, Yang, Xuesong, Xiao, Feizhe, Liu, Dawei, Yang, Lixuan, Zhang, Nu

“…In the published article [1], an error was noticed in Fig. 6B. The western blot results were reversed between the overexpression group and the knockdown group…”
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Novel Role of FBXW7 Circular RNA in Repressing Glioma Tumorigenesis by Yang, Yibing, Gao, Xinya, Zhang, Maolei, Yan, Sheng, Sun, Chengjun, Xiao, Feizhe, Huang, Nunu, Yang, Xuesong, Zhao, Kun, Zhou, Huangkai, Huang, Suyun, Xie, Bo, Zhang, Nu

“…Circular RNAs (circRNAs) are RNA transcripts that are widespread in the eukaryotic genome. Recent evidence indicates that circRNAs play important roles in…”
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Rolling-translated EGFR variants sustain EGFR signaling and promote glioblastoma tumorigenicity by Liu, Yi, Li, Zhongjun, Zhang, Maolei, Zhou, Huangkai, Wu, Xujia, Zhong, Jian, Xiao, Feizhe, Huang, Nunu, Yang, Xuesong, Zeng, Rong, Yang, Lixuan, Xia, Zhibo, Zhang, Nu

“…Abstract Background Aberrant epidermal growth factor receptor (EGFR) activation is observed in over 50% of cases of adult glioblastoma (GBM). Nevertheless,…”
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An Upstream Open Reading Frame in Phosphatase and Tensin Homolog Encodes a Circuit Breaker of Lactate Metabolism by Huang, Nunu, Li, Fanying, Zhang, Maolei, Zhou, Huangkai, Chen, Zhipeng, Ma, Xiaoyan, Yang, Lixuan, Wu, Xujia, Zhong, Jian, Xiao, Feizhe, Yang, Xuesong, Zhao, Kun, Li, Xixi, Xia, Xin, Liu, Zexian, Gao, Song, Zhang, Nu

“…The metabolic role of micropeptides generated from untranslated regions remains unclear. Here we describe MP31, a micropeptide encoded by the upstream open…”
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Distinct roles of TREM2 in central nervous system cancers and peripheral cancers by Zhong, Jian, Xing, Xudong, Gao, Yixin, Pei, Lei, Lu, Chenfei, Sun, Huixin, Lai, Yanxing, Du, Kang, Xiao, Feizhe, Yang, Ying, Wang, Xiuxing, Shi, Yu, Bai, Fan, Zhang, Nu

“…Glioblastomas (GBM) are incurable central nervous system (CNS) cancers characterized by substantial myeloid cell infiltration. Whether myeloid cell-directed…”
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Upstream open reading frame-encoded MP31 disrupts the mitochondrial quality control process and inhibits tumorigenesis in glioblastoma by Huang, Nunu, Chen, Zhipeng, Yang, Xuesong, Gao, Yixin, Zhong, Jian, Li, Yan, Xiao, Feizhe, Wang, Xiuxing, Shi, Yu, Zhang, Nu

“…Abstract Background Mitochondrial hyperpolarization achieved by the elevation of mitochondrial quality control (MQC) activity is a hallmark of glioblastoma…”
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A novel protein RASON encoded by a lncRNA controls oncogenic RAS signaling in KRAS mutant cancers by Cheng, Rongjie, Li, Fanying, Zhang, Maolei, Xia, Xin, Wu, Jianzhuang, Gao, Xinya, Zhou, Huangkai, Zhang, Zhi, Huang, Nunu, Yang, Xuesong, Zhang, Yaliang, Shen, Shunli, Kang, Tiebang, Liu, Zexian, Xiao, Feizhe, Yao, Hongwei, Xu, Jianbo, Yan, Chao, Zhang, Nu

“…Mutations of the RAS oncogene are found in around 30% of all human cancers yet direct targeting of RAS is still considered clinically impractical except for…”
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An Upstream Open Reading Frame in Phosphatase and Tensin Homolog Encodes a Circuit Breaker of Lactate Metabolism by Huang, Nunu, Li, Fanying, Zhang, Maolei, Zhou, Huangkai, Chen, Zhipeng, Ma, Xiaoyan, Yang, Lixuan, Wu, Xujia, Zhong, Jian, Xiao, Feizhe, Yang, Xuesong, Zhao, Kun, Li, Xixi, Xia, Xin, Liu, Zexian, Gao, Song, Zhang, Nu

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Lnc-H19-derived protein shapes the immunosuppressive microenvironment of glioblastoma by Chen, Junju, Gao, Yixin, Zhong, Jian, Wu, Xujia, Leng, Zhaojie, Liu, Ming, Wang, Yesheng, Wang, Yuan, Yang, Xuesong, Huang, Nunu, Xiao, Feizhe, Zhang, Maolei, Liu, Xuesong, Zhang, Nu

“…The immunosuppressive tumor microenvironment (TME) is a prominent feature of glioblastoma (GBM), the most lethal primary brain cancer resistant to current…”
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