Search Results - "Xiao, Chunsheng"

Reactive Oxygen Species (ROS) Responsive Polymers for Biomedical Applications by Xu, Qinghua, He, Chaoliang, Xiao, Chunsheng, Chen, Xuesi

“…Reactive oxygen species (ROS) play important roles in cell signaling pathways, while increased production of ROS may disrupt cellular homeostasis, giving rise…”
Get full text

A Multistage Cooperative Nanoplatform Enables Intracellular Co‐Delivery of Proteins and Chemotherapeutics for Cancer Therapy by Zhang, Peng, Zhang, Yu, Ding, Xiaoya, Shen, Wei, Li, Mingqian, Wagner, Ernst, Xiao, Chunsheng, Chen, Xuesi

“…Combining intracellularly active proteins with chemotherapeutics represents a promising strategy for synergistic cancer therapy. However, the lack of…”
Get full text

Biodegradable pH-responsive polyacrylic acid derivative hydrogels with tunable swelling behavior for oral delivery of insulin by Gao, Xiaoye, He, Chaoliang, Xiao, Chunsheng, Zhuang, Xiuli, Chen, Xuesi

“…Novel biodegradable and pH-sensitive hydrogels composed of four types of pH-sensitive polyacrylic acid derivatives (PAAD) and a biodegradable poly(l-glutamic…”
Get full text

Engineered hydrogels for peripheral nerve repair by Liu, Yao, Zhang, Xiaonong, Xiao, Chunsheng, Liu, Bin

“…Peripheral nerve injury (PNI) is a complex disease that often appears in young adults. It is characterized by a high incidence, limited treatment options, and…”
Get full text

Preclinical Evaluation of Antitumor Activity of Acid-Sensitive PEGylated Doxorubicin by Sun, Diankui, Ding, Jianxun, Xiao, Chunsheng, Chen, Jinjin, Zhuang, Xiuli, Chen, Xuesi

“…The acid-sensitive PEGylated doxorubicin (DOX) with exact chemical structure was designed and prepared as a potential tumor intracellular…”
Get full text

Facile Synthesis of Glycopolypeptides by Combination of Ring-Opening Polymerization of an Alkyne-Substituted N-carboxyanhydride and Click "Glycosylation" by Xiao, Chunsheng, Zhao, Changwen, He, Pan, Tang, Zhaohui, Chen, Xuesi, Jing, Xiabin

“…Synthetic glycopolypeptides have attracted much interest for application in biomedical field as they are structural mimics to the natural glycopeptides or…”
Get full text

Polymeric nanomedicines for the treatment of hepatic diseases by Luo, Feixiang, Yu, Ying, Li, Mingqian, Chen, Yuguo, Zhang, Peng, Xiao, Chunsheng, Lv, Guoyue

“…Abstract The liver is an important organ in the human body and performs many functions, such as digestion, detoxification, metabolism, immune responses, and…”
Get full text

From oncolytic peptides to oncolytic polymers: A new paradigm for oncotherapy by Liu, Hanmeng, Shen, Wei, Liu, Wanguo, Yang, Zexin, Yin, Dengke, Xiao, Chunsheng

“…Traditional cancer therapy methods, especially those directed against specific intracellular targets or signaling pathways, are not powerful enough to overcome…”
Get full text

Quantitation of Glutathione by Quinoline-5, 8-Dione-Based Tag Strategy Using MALDI Mass Spectrometry by Guo, Liming, Xiao, Chunsheng, Wang, Sheng, Gao, Tianyang, Ling, Ling, Guo, Xinhua

“…In the present work, we developed an UV-absorptive and highly reactive tag aromatic molecule, quinoline-5,8-dione (QLD), for robust quantitative analysis of…”
Get full text

A sulfur dioxide polymer prodrug showing combined effect with doxorubicin in combating subcutaneous and metastatic melanoma by An, Lin, Zhang, Peng, Shen, Wei, Yi, Xuan, Yin, Weitian, Jiang, Rihua, Xiao, Chunsheng

“…Melanoma, as the most aggressive and treatment-resistant skin malignancy, is responsible for about 80% of all skin cancer mortalities. Prone to invade into the…”
Get full text

Decisive Role of Hydrophobic Side Groups of Polypeptides in Thermosensitive Gelation by Cheng, Yilong, He, Chaoliang, Xiao, Chunsheng, Ding, Jianxun, Zhuang, Xiuli, Huang, Yubin, Chen, Xuesi

“…Thermosensitive hydrogels based on PEG and poly(l-glutamate)s bearing different hydrophobic side groups were separately synthesized by the ring-opening…”
Get full text

CD44-targeting hyaluronic acid-selenium nanoparticles boost functional recovery following spinal cord injury by Luo, Wenqi, Li, Yueying, Zhao, Jianhui, Niu, Renrui, Xiang, Chunyu, Zhang, Mingyu, Xiao, Chunsheng, Liu, Wanguo, Gu, Rui

“…Therapeutic strategies based on scavenging reactive oxygen species (ROS) and suppressing inflammatory cascades are effective in improving functional recovery…”
Get full text

Multi-Sensor Based Online Attitude Estimation and Stability Measurement of Articulated Heavy Vehicles by Zhu, Qingyuan, Xiao, Chunsheng, Hu, Huosheng, Liu, Yuanhui, Wu, Jinjin

“…Articulated wheel loaders used in the construction industry are heavy vehicles and have poor stability and a high rate of accidents because of the…”
Get full text

Synthesis of polypeptide bearing 1,4-dithiane pendants for ROS-responsive drug release by Zhang, Tianhui, Yao, Jiuxu, Tian, Jiamei, Deng, Mingxiao, Zhuang, Xiuli, Xiao, Chunsheng

“…A new kind of polypeptide bearing 1,4-dithiane pendants was synthesized and used for reactive oxygen species (ROS)-responsive drug release. [Display omitted]…”
Get full text

Minocycline-Loaded Poly(α-Lipoic Acid)-Methylprednisolone Prodrug Nanoparticles for the Combined Anti-Inflammatory Treatment of Spinal Cord Injury by Lin, Feng, Liu, Yixuan, Luo, Wenqi, Liu, Shuhan, Wang, Yiming, Gu, Rui, Liu, Wanguo, Xiao, Chunsheng

“…Traumatic spinal cord injury (TSCI) induces a powerful inflammatory response that can significantly exacerbate the extent and severity of neural damage (termed…”
Get full text

Correction Technique of Inertial Force and Moment in Direct Force Measuring Test of Dynamic Aerodynamic Performance of Airfoils by Jiao, Yuqin, Xiao, Chunsheng, Wu, Dengke

“…The research on both direct force measuring test technique of dynamic aerodynamic performance of oscillating airfoils in low-speed flow and inertial force and…”
Get full text

Multidentate Comb-Shaped Polypeptides Bearing Trithiocarbonate Functionality: Synthesis and Application for Water-Soluble Quantum Dots by Zhang, Hang, Chen, Jinlong, Zhang, Xiaojie, Xiao, Chunsheng, Chen, Xuesi, Tao, Youhua, Wang, Xianhong

“…We describe here the synthesis of multidentate comb-shaped polypeptides bearing trithiocarbonate functionality and their application in the preparation of…”
Get full text

Versatile Biofunctionalization of Polypeptide-Based Thermosensitive Hydrogels via Click Chemistry by Cheng, Yilong, He, Chaoliang, Xiao, Chunsheng, Ding, Jianxun, Cui, Haitao, Zhuang, Xiuli, Chen, Xuesi

“…In this study, we report thermosensitive hydrogels based on poly(ethylene glycol)-block-poly(γ-propargyl-l-glutamate) (PEG-PPLG). 13C NMR spectra, DLS, and…”
Get full text

Highly Efficient "Grafting From" an α-Helical Polypeptide Backbone by Atom Transfer Radical Polymerization by Ding, Jianxun, Xiao, Chunsheng, Tang, Zhaohui, Zhuang, Xiuli, Chen, Xuesi

“…Because of their favorable biodegradability, biocompatibility, regular secondary structures, and stimuli‐responsiveness, synthetic polypeptides have attracted…”
Get full text

Recent advances in nanomaterials for the treatment of spinal cord injury by Gong, Weiquan, Zhang, Tianhui, Che, Mingxue, Wang, Yongjie, He, Chuanyu, Liu, Lidi, Lv, Zhenshan, Xiao, Chunsheng, Wang, Hao, Zhang, Shaokun

“…Spinal cord injuries (SCIs) are devastating. In SCIs, a powerful traumatic force impacting the spinal cord results in the permanent loss of nerve function…”
Get full text