Search Results - "Xiao, Chuanle"
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A human circulating immune cell landscape in aging and COVID-19
Published in Protein & cell (01-10-2020)“…Age-associated changes in immune cells have been linked to an increased risk for infection. However, a global and detailed characterization of the changes that…”
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2
Single-cell analysis of isoform switching and transposable element expression during preimplantation embryonic development
Published in PLoS biology (16-02-2024)“…Alternative splicing is an essential regulatory mechanism for development and pathogenesis. Through alternative splicing one gene can encode multiple isoforms…”
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3
De novo diploid genome assembly using long noisy reads
Published in Nature communications (05-04-2024)“…The high sequencing error rate has impeded the application of long noisy reads for diploid genome assembly. Most existing assemblers failed to generate…”
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4
Transfer RNAs Mediate the Rapid Adaptation of Escherichia coli to Oxidative Stress
Published in PLoS genetics (01-06-2015)“…Translational systems can respond promptly to sudden environmental changes to provide rapid adaptations to environmental stress. Unlike the well-studied…”
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A high heterozygosity genome assembly of Aedes albopictus enables the discovery of the association of PGANT3 with blood-feeding behavior
Published in BMC genomics (03-04-2024)“…The Asian tiger mosquito, Aedes albopictus, is a global invasive species, notorious for its role in transmitting dangerous human arboviruses such as dengue and…”
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6
Compacting a synthetic yeast chromosome arm
Published in Genome Biology (04-01-2021)“…Redundancy is a common feature of genomes, presumably to ensure robust growth under different and changing conditions. Genome compaction, removing sequences…”
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Low-cost, Low-bias and Low-input RNA-seq with High Experimental Verifiability based on Semiconductor Sequencing
Published in Scientific reports (21-04-2017)“…Low-input RNA-seq is powerful to represent the gene expression profiles with limited number of cells, especially when single-cell variations are not the aim…”
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Integrated single-cell analysis revealed immune dynamics during Ad5-nCoV immunization
Published in Cell discovery (10-08-2021)“…Coronavirus disease 2019 (COVID-19), driven by SARS-CoV-2, is a severe infectious disease that has become a global health threat. Vaccines are among the most…”
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Environmental Water and Sediment Microbial Communities Shape Intestine Microbiota for Host Health: The Central Dogma in an Anthropogenic Aquaculture Ecosystem
Published in Frontiers in microbiology (02-11-2021)“…From increasing evidence has emerged a tight link among the environment, intestine microbiota, and host health status; moreover, the microbial interaction in…”
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Applications and potentials of nanopore sequencing in the (epi)genome and (epi)transcriptome era
Published in Innovation (New York, NY) (28-11-2021)“…The Human Genome Project opened an era of (epi)genomic research, and also provided a platform for the development of new sequencing technologies. During and…”
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Phosphoproteome analysis of the pathogenic bacterium Helicobacter pylori reveals over-representation of tyrosine phosphorylation and multiply phosphorylated proteins
Published in Proteomics (Weinheim) (01-04-2011)“…Increasing evidence shows that protein phosphorylation on serine (Ser), threonine (Thr) and tyrosine (Tyr) residues is a major regulatory post‐translational…”
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Putative cobalt- and nickel-binding proteins and motifs in Streptococcus pneumoniae
Published in Metallomics (01-06-2013)“…Cobalt and nickel play important roles in various biological processes. The present work focuses on the enrichment and identification of Co- and Ni-binding…”
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Lipoprotein FtsB in Streptococcus pyogenes binds ferrichrome in two steps with residues Tyr137 and Trp204 as critical ligands
Published in PloS one (20-06-2013)“…Lipoprotein FtsB is a component of the FtsABCD transporter that is responsible for ferrichrome binding and uptake in the Gram-positive pathogen Streptococcus…”
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14
Author Correction: Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing
Published in Cell discovery (20-06-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Immune cell profiling of COVID-19 patients in the recovery stageby single-cell sequencing
Published in Cell discovery (04-05-2020)“…COVID-19, caused by SARS-CoV-2, has recently affected over 1,200,000 people and killed more than 60,000. The key immune cell subsets change and their states…”
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Identification of ubiquitinated proteins from human multiple myeloma U266 cells by proteomics
Published in Biomedical and environmental sciences (01-08-2011)“…To identify ubiquitinated proteins from complex human multiple myeloma (MM) U266 cells, a malignant disorder of differentiated human B cells. Employing a…”
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MethSMRT: an integrative database for DNA N6-methyladenine and N4-methylcytosine generated by single-molecular real-time sequencing
Published in Nucleic acids research (04-01-2017)“…DNA methylation is an important type of epigenetic modifications, where 5- methylcytosine (5mC), 6-methyadenine (6mA) and 4-methylcytosine (4mC) are the most…”
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Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing
Published in Cell discovery (04-05-2020)“…COVID-19, caused by SARS-CoV-2, has recently affected over 1,200,000 people and killed more than 60,000. The key immune cell subsets change and their states…”
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Targeting inflammasomes and pyroptosis in retinal diseases—molecular mechanisms and future perspectives
Published in Progress in retinal and eye research (01-07-2024)“…Retinal diseases encompass various conditions associated with sight-threatening immune responses and are leading causes of blindness worldwide. These diseases…”
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Semi-automated assembly of high-quality diploid human reference genomes
Published in Nature (London) (17-11-2022)“…The current human reference genome, GRCh38, represents over 20 years of effort to generate a high-quality assembly, which has benefitted society 1 , 2 …”
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