Search Results - "Xiao, Chenghua"

IL-21 enhances STAT3/Blimp-1 signaling pathway in B cells and contributes to plasma cell differentiation in newly diagnosed patients with myasthenia gravis by Xu, Yanan, Huang, Xiaoyu, Li, Fengzhan, Liu, Tan, Yang, Tingting, Chen, Fei, Zhu, Jie, Pan, Meng, Zhang, Yong, Wang, Yuzhong, Fu, Linlin, Xiao, Chenghua, Geng, Deqin

“…The transcription factor Blimp-1 is necessary for the B cell differentiation toward immunoglobulin-secreting plasma cells. However, the immunopathological…”
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Association between interleukin gene polymorphisms and susceptibility to gastric cancer in the Qinghai population by Song, Xiaoyan, Wang, Dongmei, Ben, Baji, Xiao, Chenghua, Bai, Liyan, Xiao, Han, Zhang, Wenyan, Li, Wanchao, Jia, Jingying, Qi, Yujuan

“…Objective To investigate the associations between interleukin (IL) gene polymorphisms and susceptibility to gastric cancer in the Qinghai population, China…”
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Altered expression of transcription factors IRF4 and IRF8 in peripheral blood B cells is associated with clinical severity and circulating plasma cells frequency in patients with myasthenia gravis by Zhang, Yong, Jia, Xiao, Xia, Yan, Li, Hao, Chen, Fei, Zhu, Jie, Zhang, Xiuying, Zhang, Yanyan, Wang, YuZhong, Xu, Yanan, Pan, Meng, Huang, Xiaoyu, Yu, Tingyan, Fu, Linlin, Xiao, Chenghua, Geng, Deqin

“…Previous studies have shown that interferon regulatory factor-4 (IRF4) and IRF8 play critical but distinct roles in the differentiation of B cells into plasma…”
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Role of calbindin-D28K in estrogen treatment for Parkinson's disease by Wang, Chunhua, Jiang, Chao, Yuan, Honghua, Xiao, Chenghua, Gao, Dianshuai

“…Studies have shown that estrogen has neuroprotective effects on the nigrostriatal system. The present study established a Parkinson's disease model in C57BL/6…”
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Secretory Clusterin Inhibits Dopamine Neuron Apoptosis in MPTP Mice by Preserving Autophagy Activity by Zhu, Dongxue, Zhang, Shenyang, Wang, Xiaoying, Xiao, Chenghua, Cui, Guiyun, Yang, Xinxin

“…•sCLU treatment could improve motor deficits in an MPTP-induced mouse model of PD.•sCLU intervention inhibited MPTP-induced apoptosis.•sCLU treatment inhibited…”
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Increased Expression of CD95 in CD4+ Effector Memory T Cells Promotes Th17 Response in Patients with Myasthenia Gravis by Huang, Xiaoyu, Zhu, Jie, Liu, Tan, Li, Fengzhan, Yang, Tingting, Li, Hao, Chen, Fei, Zhang, Yong, Wang, Yuzhong, Fu, Linlin, Xiao, Chenghua, Geng, Deqin

“…Emerging data have revealed that CD95 can evoke non-apoptotic signals, thereby promoting pro-inflammatory functions that link to the severity of autoimmune…”
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Artesunate Attenuates Lipopolysaccharide-Stimulated Proinflammatory Responses by Suppressing TLR4, MyD88 Expression, and NF-κB Activation in Microglial Cells by Wang, Dunjing, Shi, Jun, Lv, Shuiqing, Xu, Weiwei, Li, Jizhen, Ge, Wei, Xiao, Chenghua, Geng, Deqin, Liu, Yonghai

“…Microglia are considered as a major target in the prevention of neuroinflammation by modulating the production of pro-inflammatory mediators. Artesunate, a…”
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Increased expression of P2X7 receptor in peripheral blood mononuclear cells correlates with clinical severity and serum levels of Th17-related cytokines in patients with myasthenia gravis by Zhang, Yong, Zhang, Yanyan, Li, Hao, Jia, Xiao, Zhang, Xiuying, Xia, Yan, Wang, YuZhong, Fu, Linlin, Xiao, Chenghua, Geng, Deqin

“…Highlights • P2X7R was significantly increased in PBMC from MG • Expression of P2X7R was positively correlated with QMG score of MG • Expression of P2X7R was…”
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RNA interference targeting Bcl-6 ameliorates experimental autoimmune myasthenia gravis in mice by Xin, Ning, Fu, Linlin, Shao, Zhen, Guo, Mingfeng, Zhang, Xiuying, Zhang, Yong, Dou, Changxin, Zheng, Shuangshuang, Shen, Xia, Yao, Yuanhu, Wang, Jiao, Wang, Jinhua, Cui, Guiyun, Liu, Yonghai, Geng, Deqin, Xiao, Chenghua, Zhang, Zunsheng, Dong, Ruiguo

“…Follicular helper T (Tfh) cells are dedicated to providing help to B cells and are strongly associated with antibody-mediated autoimmune disease. B cell…”
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TIPE2 Play a Negative Role in TLR4-Mediated Autoimmune T Helper 17 Cell Responses in Patients with Myasthenia Gravis by Zhang, Yong, Shao, Zhen, Zhang, Xiuying, Jia, Xiao, Xia, Yan, Zhang, Yanyan, Xin, Ning, Guo, Mingfeng, Chen, Jing, Zheng, ShuangShuang, Wang, YuZhong, Fu, Linlin, Dong, Ruiguo, Xiao, Chenghua, Geng, Deqin, Liu, Yonghai

“…Th17-related cytokines have been suggested to play a crucial role in myasthenia gravis (MG) pathogenesis.The tumor necrosis factor (TNF)-α-induced protein…”
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Decreased microRNA miR-181c expression in peripheral blood mononuclear cells correlates with elevated serum levels of IL-7 and IL-17 in patients with myasthenia gravis by Zhang, Yong, Guo, Mingfeng, Xin, Ning, Shao, Zhen, Zhang, Xiuying, Zhang, Yanyan, Chen, Jing, Zheng, Shuangshuang, Fu, Linlin, Wang, YuZhong, Zhou, Dongmei, Chen, Hao, Huang, Yan, Dong, Ruiguo, Xiao, Chenghua, Liu, Yonghai, Geng, Deqin

“…miR-181c is a newly identified negative regulator of immune cell activation. In this study, we aimed to investigate the expression and functional role of…”
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Identification of Novel MicroRNA Signatures Linked to Experimental Autoimmune Myasthenia Gravis Pathogenesis: Down-Regulated miR-145 Promotes Pathogenetic Th17 Cell Response by Wang, Jiao, Zheng, Shuangshuang, Xin, Ning, Dou, Changxin, Fu, Linlin, Zhang, Xiuying, Chen, Jing, Zhang, Yanyan, Geng, Deqin, Xiao, Chenghua, Cui, Guiyun, Shen, Xia, Lu, Yang, Wang, Jinhua, Dong, Ruiguo, Qiao, Yuehua, Zhang, Yong

“…Emerging evidence demonstrates that miRNAs, a new family of key mRNA regulatory molecules, have crucial roles in controlling and modulating immunity. Their…”
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CD19+ Tim-1+ B cells are decreased and negatively correlated with disease severity in Myasthenia Gravis patients by Zhang, Yong, Zhang, Xiuying, Xia, Yan, Jia, Xiao, Li, Hao, Zhang, Yanyan, Shao, Zhen, Xin, Ning, Guo, Mingfeng, Chen, Jing, Zheng, ShuangShuang, Wang, YuZhong, Fu, Linlin, Xiao, Chenghua, Geng, Deqin, Liu, Yonghai, Cui, Guiyun, Dong, Ruiguo, Huang, Xiaoyu, Yu, Tingyan

“…T cell immunoglobulin mucin domain-1(Tim-1) was recently identified to be critical and essential for optimal regulatory B cells function in maintaining immune…”
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Efficacy and Safety of Ginkgo Diterpene Lactone Meglumine in Acute Ischemic Stroke: A Randomized Clinical Trial by Zhang, Qian, Wang, Anxin, Xu, Qin, Xia, Xue, Tian, Xue, Zhang, Yijun, Li, Xiaolong, Yang, Xiusheng, Wang, Xingchen, Peng, Jinghua, Li, Yanchun, Liu, Luran, Jin, Shunshan, Meng, Xia, Zhao, Xingquan

“…Ginkgo diterpene lactone meglumine (GDLM) has attracted much attention because of its potential neuroprotective properties in ischemic stroke. The efficacy of…”
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Artesunate Attenuates Lipopolysaccharide-Stimulated Proinflammatory Responses by Suppressing TLR4, MyD88 Expression, and NF-[kappa]B Activation in Microglial Cells by Wang, Dunjing, Shi, Jun, Lv, Shuiqing, Xu, Weiwei, Li, Jizhen, Ge, Wei, Xiao, Chenghua, Geng, Deqin, Liu, Yonghai

“…Microglia are considered as a major target in the prevention of neuroinflammation by modulating the production of pro-inflammatory mediators. Artesunate, a…”
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Role of calbindin-D28K in estrogen treatment for Parkinson′s disease by Wang, Chunhua, Jiang, Chao, Yuan, Honghua, Xiao, Chenghua, Gao, Dianshuai

“…Abstract Studies have shown that estrogen has neuroprotective effects on the nigrostriatal system. The present study established a Parkinson′s disease model in…”
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Direct observation of Pt nanocrystal coalescence induced by electron-excitation-enhanced van der Waals interactions by Jiang, Ying, Wang, Yong, Zhang, Yu Yang, Zhang, Zhengfei, Yuan, Wentao, Sun, Chenghua, Wei, Xiao, Brodsky, Casey N., Tsung, Chia-Kuang, Li, Jixue, Zhang, Xiaofeng, Mao, Scott X., Zhang, Shengbai, Zhang, Ze

“…Nanocrystal coalescence has attracted paramount attention in nanostructure fabrication in the past decades. Tremendous endeavor and progress have been made in…”
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