Search Results - "Xiangwei, Gao"
-
1
Quantitative profiling of initiating ribosomes in vivo
Published in Nature methods (01-02-2015)“…QTI-seq (quantitative translation initiation sequencing) maps the position of the start codon and thus allows the determination of initiation efficiency in…”
Get full text
Journal Article -
2
Discovery of the hidden coding information in cancers: Mechanisms and biological functions
Published in International journal of cancer (01-07-2023)“…Most proteins are derived from the translation of coding sequence (CDS) in messenger RNAs (mRNAs). However, accumulating evidence has revealed an unexpected…”
Get full text
Journal Article -
3
The emerging role of follistatin under stresses and its implications in diseases
Published in Gene (10-01-2018)“…Follistatin (FST), a single-chain glycosylated protein, is expressed in various tissues. The essential biological function of FST is binding and neutralizing…”
Get full text
Journal Article -
4
Land-Cover Classification of Coastal Wetlands Using the RF Algorithm for Worldview-2 and Landsat 8 Images
Published in Remote sensing (Basel, Switzerland) (01-08-2019)“…Wetlands are one of the world’s most important ecosystems, playing an important role in regulating climate and protecting the environment. However, human…”
Get full text
Journal Article -
5
Translational control of the cytosolic stress response by mitochondrial ribosomal protein L18
Published in Nature structural & molecular biology (01-05-2015)“…A stress-induced cytosolic isoform of the mitochondrial ribosomal protein MRPL18 facilitates the specific translation of heat-shock proteins during the general…”
Get full text
Journal Article -
6
SIRT6 Inhibits Anoikis of Colorectal Cancer Cells by Down-Regulating NDRG1
Published in International journal of molecular sciences (01-06-2024)“…Anoikis, a form of apoptosis resulting from the loss of cell-extracellular matrix interaction, is a significant barrier to cancer cell metastasis. However, the…”
Get full text
Journal Article -
7
Autophagic flux blockage in alveolar epithelial cells is essential in silica nanoparticle-induced pulmonary fibrosis
Published in Cell death & disease (12-02-2019)“…Silica nanoparticles (SiNPs) have been reported to induce pulmonary fibrosis (PF) with an unknown mechanism. Recently, the activation of autophagy, a…”
Get full text
Journal Article -
8
Adipocyte YTH N(6)-methyladenosine RNA-binding protein 1 protects against obesity by promoting white adipose tissue beiging in male mice
Published in Nature communications (13-03-2023)“…Obesity, one of the most serious public health issues, is caused by the imbalance of energy intake and energy expenditure. N(6)-methyladenosine (m 6 A) RNA…”
Get full text
Journal Article -
9
Myeloid cells protect intestinal epithelial barrier integrity through the angiogenin/plexin‐B2 axis
Published in The EMBO journal (01-07-2020)“…Communication between myeloid cells and epithelium plays critical role in maintaining intestinal epithelial barrier integrity. Myeloid cells interact with…”
Get full text
Journal Article -
10
Angiogenin Stimulates Ribosomal RNA Transcription by Epigenetic Activation of the Ribosomal DNA Promoter
Published in Journal of cellular physiology (01-04-2014)“…Angiogenin (ANG) undergoes nuclear translocation and promotes ribosomal RNA (rRNA) transcription thereby enhancing cell growth and proliferation. However, the…”
Get full text
Journal Article -
11
The Induction of Yes-Associated Protein Expression After Arterial Injury Is Crucial for Smooth Muscle Phenotypic Modulation and Neointima Formation
Published in Arteriosclerosis, thrombosis, and vascular biology (01-11-2012)“…OBJECTIVE—Abnormal proliferation and migration of vascular smooth muscle cells (SMCs) are the key events in the progression of neointima formation in response…”
Get full text
Journal Article -
12
The Ecological Risks in Arid Zones from a Production–Living–Ecological Space Perspective: A Case Study of the Tuha Region in Xinjiang, China
Published in Remote sensing (Basel, Switzerland) (01-09-2024)“…The ecological and environmental problems of arid zones have become an urgent global concern. Current research on ecological risk is based mainly on the…”
Get full text
Journal Article -
13
Reduction of AUF1-mediated follistatin mRNA decay during glucose starvation protects cells from apoptosis
Published in Nucleic acids research (15-09-2014)“…Follistatin (FST) performs several vital functions in the cells, including protection from apoptosis during stress. The expression of FST is up-regulated in…”
Get full text
Journal Article -
14
Inhibition of RNA polymerase III transcription by Triptolide attenuates colorectal tumorigenesis
Published in Journal of experimental & clinical cancer research (23-05-2019)“…Upregulation of RNA polymerase (Pol) III products, including tRNAs and 5S rRNA, in tumor cells leads to enhanced protein synthesis and tumor formation, making…”
Get full text
Journal Article -
15
Angiogenin enhances cell migration by regulating stress fiber assembly and focal adhesion dynamics
Published in PloS one (14-12-2011)“…Angiogenin (ANG) acts on both vascular endothelial cells and cancer cells, but the underlying mechanism remains elusive. In this study, we carried out a…”
Get full text
Journal Article -
16
Ribosome profiling reveals sequence-independent post-initiation pausing as a signature of translation
Published in Cell research (01-07-2014)“…The journey of a newly synthesized polypeptide starts in the peptidyltransferase center of the ribosome, from where it traverses the exit tunnel. The interior…”
Get full text
Journal Article -
17
Transcriptional activation of follistatin by Nrf2 protects pulmonary epithelial cells against silica nanoparticle-induced oxidative stress
Published in Scientific reports (16-02-2016)“…Silica nanoparticles (SiO 2 NPs) cause oxidative stress in respiratory system. Meanwhile, human cells launch adaptive responses to overcome SiO 2 NP toxicity…”
Get full text
Journal Article -
18
The Influence of CLBP Window Size on Urban Vegetation Type Classification Using High Spatial Resolution Satellite Images
Published in Remote sensing (Basel, Switzerland) (01-10-2020)“…Urban vegetation can regulate ecological balance, reduce the influence of urban heat islands, and improve human beings’ mental state. Accordingly,…”
Get full text
Journal Article -
19
Identification of estrogen receptor-related receptor gamma as a direct transcriptional target of angiogenin
Published in PloS one (15-08-2013)“…Nuclear translocation of angiogenin (ANG) is essential for the proliferation of its target cells. ANG promotes rRNA synthesis, while whether it regulates mRNA…”
Get full text
Journal Article -
20
Dynamic m6A mRNA methylation directs translational control of heat shock response
Published in Nature (London) (12-10-2015)“…Under stress, such as heat shock, the N 6 -methyladenosine (m 6 A) modification is shown to accumulate primarily in the 5′ untranslated region of induced mRNAs…”
Get full text
Journal Article