Search Results - "Xiangnan, Zhang"

BNIP3L/NIX-mediated mitophagy: molecular mechanisms and implications for human disease by Li, Yue, Zheng, Wanqing, Lu, Yangyang, Zheng, Yanrong, Pan, Ling, Wu, Xiaoli, Yuan, Yang, Shen, Zhe, Ma, Shijia, Zhang, Xingxian, Wu, Jiaying, Chen, Zhong, Zhang, Xiangnan

“…Mitophagy is a highly conserved cellular process that maintains the mitochondrial quantity by eliminating dysfunctional or superfluous mitochondria through…”
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PD-1 inhibitors increase the incidence and risk of pneumonitis in cancer patients in a dose-independent manner: a meta-analysis by Wu, Jiaying, Hong, Dongsheng, Zhang, Xiangnan, Lu, Xiaoyang, Miao, Jing

“…Therapies that targeted PD-1 have shown remarkable rates of durable clinical responses in patients with various tumor types. However, the extent and knowledge…”
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BNIP3L/NIX-mediated mitophagy protects against ischemic brain injury independent of PARK2 by Yuan, Yang, Zheng, Yanrong, Zhang, Xiangnan, Chen, Ying, Wu, Xiaoli, Wu, Jiaying, Shen, Zhe, Jiang, Lei, Wang, Lu, Yang, Wei, Luo, Jianhong, Qin, Zhenghong, Hu, Weiwei, Chen, Zhong

“…Cerebral ischemia induces massive mitochondrial damage. These damaged mitochondria are cleared, thus attenuating brain injury, by mitophagy. Here, we…”
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Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance by Zhang, Xiangnan, Yan, Haijing, Yuan, Yang, Gao, Jieqiong, Shen, Zhe, Cheng, Yun, Shen, Yao, Wang, Rong-Rong, Wang, Xiaofen, Hu, Wei-Wei, Wang, Guanghui, Chen, Zhong

“…Cerebral ischemia-reperfusion (I-R) is a complex pathological process. Although autophagy can be evoked by ischemia, its involvement in the reperfusion phase…”
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An efficient and universal polygon prediction method based on derivable analytic geometry for arbitrary-shaped text detection by Zhang, Xiangnan, Tian, Chunna, Gao, Xinbo

“…A polygon can represent the boundary of curved text more compactly than a rectangle. However, predicting reasonable polygon lacks of solutions due to the…”
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Rapid Monitoring Approach for Microplastics Using Portable Pyrolysis-Mass Spectrometry by Zhang, Xiangnan, Zhang, Hong, Yu, Kai, Li, Na, Liu, Yuning, Liu, Xiangyu, Zhang, Hengnan, Yang, Bin, Wu, Wenhai, Gao, Jing, Jiang, Jie

“…Microplastics (MPs) pollution has drawn increasing concern due to its widespread occurrence and potential risks in the environment. The reliable methods and…”
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Somatic autophagy of axonal mitochondria in ischemic neurons by Zheng, Yanrong, Zhang, Xiangnan, Wu, Xiaoli, Jiang, Lei, Ahsan, Anil, Ma, Shijia, Xiao, Ziyu, Han, Feng, Qin, Zheng-Hong, Hu, Weiwei, Chen, Zhong

“…Mitophagy protects against ischemic neuronal injury by eliminating damaged mitochondria, but it is unclear how mitochondria in distal axons are cleared. We…”
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Histamine H1 receptor deletion in cholinergic neurons induces sensorimotor gating ability deficit and social impairments in mice by Cheng, Li, Xu, Cenglin, Wang, Lu, An, Dadao, Jiang, Lei, Zheng, Yanrong, Xu, Yixin, Wang, Yi, Wang, Yujing, Zhang, Kuo, Wang, Xiaodong, Zhang, Xiangnan, Bao, Aimin, Zhou, Yudong, Yang, Jingyu, Duan, Shumin, Swaab, Dick F., Hu, Weiwei, Chen, Zhong

“…Negative symptoms in schizophrenia strongly contribute to poor functional outcomes, however its pathogenesis is still unclear. Here, we found that histamine H…”
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PARK2-dependent mitophagy induced by acidic postconditioning protects against focal cerebral ischemia and extends the reperfusion window by Shen, Zhe, Zheng, Yanrong, Wu, Jiaying, Chen, Ying, Wu, Xiaoli, Zhou, Yiting, Yuan, Yang, Lu, Shousheng, Jiang, Lei, Qin, Zhenghong, Chen, Zhong, Hu, Weiwei, Zhang, Xiangnan

“…Prompt reperfusion after cerebral ischemia is critical for neuronal survival. Any strategies that extend the limited reperfusion window will be of great…”
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The primary choriocarcinoma of testis with systemic metastasis in a patient with cryptorchidism by Zhang, Xiangnan, Yang, Fan, Ma, Xiaoli, Zhao, Huanfen

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Fluorescent and colorimetric dual-mode detection of Cu2+ based on carbon dots by You, Yijun, Li, Dan, Chen, Zhuangzhuang, Zhang, Xiangnan, Hu, Yuxuan, Ouyang, Shigen, Li, Na

“…A fluorescent and colorimetric dual-mode strategy based on carbon dots (CDs) was rationally designed for sensitive determination of Cu 2+ . Green fluorescent…”
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Chlorogenic acid inhibits trimethylamine- N -oxide formation and remodels intestinal microbiota to alleviate liver dysfunction in high L-carnitine feeding mice by Zhang, Xiangnan, Shi, Lin, Chen, Rui, Zhao, Yan, Ren, Daoyuan, Yang, Xingbin

“…High L-carnitine ingestion has been shown to cause liver injury, mechanically due to an elevated circulating level of trimethylamine- -oxide (TMAO), a gut…”
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The molecular and cellular insight into the toxicology of bortezomib-induced peripheral neuropathy by Yan, Wenping, Wu, Zhanxun, Zhang, Yuyu, Hong, Dongsheng, Dong, Xihao, Liu, Lin, Rao, Yuefeng, Huang, Lili, Zhang, Xiangnan, Wu, Jiaying

“…The proteasome inhibitor bortezomib (BTZ) is a first-line antitumor drug, mainly used for multiple myeloma treatment. However, BTZ shows prominent toxicity in…”
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A Lymphoepithelioma-Like Intrahepatic Cholangiocarcinoma With Massive Multinucleated Giant Cell Reaction by Luyao, Fang, Xiangnan, Zhang, Qiaoyun, Min, Hui, Zhang, Huanping, Meng, Tianwen, Xu, Huanfen, Zhao

“…Lymphoepithelioma-like intrahepatic cholangiocarcinoma (LEL-ICC) is a rare liver tumor that appears as a hepatic nodule on imaging with a specific pathological…”
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The autophagic regulation of rosiglitazone-promoted adipocyte browning by Li, Yue, Zheng, Wanqing, Li, Xinhang, Lue, Zhengwei, Liu, Yun, Wu, Jiaying, Zhang, Xiangnan

“…Browning of white adipocytes is considered an efficient approach to combat obesity. Rosiglitazone induces the thermogenetic program of white adipocytes, but…”
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Natural compounds modulate the autophagy with potential implication of stroke by Ahsan, Anil, Liu, Mengru, Zheng, Yanrong, Yan, Wenping, Pan, Ling, Li, Yue, Ma, Shijia, Zhang, Xingxian, Cao, Ming, Wu, Zhanxun, Hu, Weiwei, Chen, Zhong, Zhang, Xiangnan

“…Stroke is considered a leading cause of mortality and neurological disability, which puts a huge burden on individuals and the community. To date, effective…”
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Privileged Biorenewable Secologanin‐Based Diversity‐Oriented Synthesis for Pseudo‐Natural Alkaloids: Uncovering Novel Neuroprotective and Antimalarial Frameworks by Zhu, Huajian, Cai, Yunrui, Ma, Shijia, Futamura, Yushi, Li, Jinbiao, Zhong, Wen, Zhang, Xiangnan, Osada, Hiroyuki, Zou, Hongbin

“…Bioprivileged molecules hold great promise for supplementing petrochemicals in sustainable organic synthesis of a diverse bioactive products library…”
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Integration of microbial metabolomics and microbiomics uncovers a novel mechanism underlying the antidiabetic property of stachyose by Yan, Tao, Liu, Tianqi, Shi, Lin, Yan, Lijing, Li, Ze, Zhang, Xiangnan, Dai, Xiaoshuang, Sun, Xiaomin, Yang, Xingbin

“…[Display omitted] •Stachyose promoted indole derivates that could improve intestinal functions and glucose metabolism.•Stachyose ameliorated type 2 diabetes…”
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Postsynaptic histamine H3 receptors in ventral basal forebrain cholinergic neurons modulate contextual fear memory by Zheng, Yanrong, Fan, Lishi, Fang, Zhuowen, Liu, Zonghan, Chen, Jiahui, Zhang, Xiangnan, Wang, Yi, Zhang, Yan, Jiang, Lei, Chen, Zhong, Hu, Weiwei

“…Overly strong fear memories can cause pathological conditions. Histamine H3 receptor (H3R) has been viewed as an optimal drug target for CNS disorders, but its…”
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Regulation of mitophagy in ischemic brain injury by Yuan, Yang, Zhang, Xiangnan, Zheng, Yanrong, Chen, Zhong

“…The selective degradation of damaged or excessive mitochondria by autophagy is termed mitophagy. Mitophagy is crucial for mitochondrial quality control and has…”
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