Search Results - "Xiangdong, Guan"

Critical care crisis and some recommendations during the COVID-19 epidemic in China by Xie, Jianfeng, Tong, Zhaohui, Guan, Xiangdong, Du, Bin, Qiu, Haibo, Slutsky, Arthur S.

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Clinical Characteristics of Patients Who Died of Coronavirus Disease 2019 in China by Xie, Jianfeng, Tong, Zhaohui, Guan, Xiangdong, Du, Bin, Qiu, Haibo

“…This case series describes the characteristics of a cohort of patients who died of coronavirus disease 2019 in China…”
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Safety and efficacy of ciprofol vs. propofol for sedation in intensive care unit patients with mechanical ventilation: a multi-center, open label, randomized, phase 2 trial by Liu, Yongjun, Yu, Xiangyou, Zhu, Duming, Zeng, Jun, Lin, Qinhan, Zang, Bin, Chen, Chuanxi, Liu, Ning, Liu, Xiao, Gao, Wei, Guan, Xiangdong

“…Ciprofol (HSK3486; Haisco Pharmaceutical Group Co., Ltd., Chengdu, China), developed as a novel 2,6-disubstituted phenol derivative showed similar tolerability…”
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Systemic Corticosteroids and Mortality in Severe and Critical COVID-19 Patients in Wuhan, China by Wu, Jianfeng, Huang, Jianqiang, Zhu, Guochao, Liu, Yihao, Xiao, Han, Zhou, Qian, Si, Xiang, Yi, Hui, Wang, Cuiping, Yang, Daya, Chen, Shuling, Liu, Xin, Liu, Zelong, Wang, Qiongya, Lv, Qingquan, Huang, Ying, Yu, Yang, Guan, Xiangdong, Li, Yanbing, Nirantharakumar, Krishnarajah, Cheng, KarKeung, Peng, Sui, Xiao, Haipeng

“…Abstract Background Systemic corticosteroids are now recommended in many treatment guidelines, although supporting evidence is limited to 1 randomized…”
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Lung ultrasound: a valuable tool for assessing COVID-19 patients with different severity by Si, Xiang, Yi, Hui, Liu, Dayue, Wang, Ruizhi, Liu, Yumei, Wu, Jianfeng, Guan, Xiangdong

“…According to the ultrasound pattern, the LUS was scored as follows: the presence of A-lines alone with lung sliding or ≤2 B-lines (0 point), ≥3 well-spaced…”
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Clinical features of 375 COVID-19 cases imported from Russia through the Suifenhe port and countermeasures by Kang, Kai, Yang, Yi, Guan, Xiangdong, Kang, Yan, Zhao, Mingyan, Yu, Jianbo, Zeng, Xiqiu, Xie, Fengjie, Chen, Guolin, Yu, Kaijiang

“…At present, the focus of the fighting against COVID-19 in China is shifting to strictly prevent the entrance of cases from abroad and disease transmission…”
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Elevation of blood glucose level predicts worse outcomes in hospitalized patients with COVID-19: a retrospective cohort study by Wu, Jianfeng, Huang, Jianqiang, Zhu, Guochao, Wang, Qiongya, Lv, Qingquan, Huang, Ying, Yu, Yang, Si, Xiang, Yi, Hui, Wang, Cuiping, Liu, Yihao, Xiao, Han, Zhou, Qian, Liu, Xin, Yang, Daya, Guan, Xiangdong, Li, Yanbing, Peng, Sui, Sung, Joseph, Xiao, Haipeng

“…IntroductionWith intense deficiency of medical resources during COVID-19 pandemic, risk stratification is of strategic importance. Blood glucose level is an…”
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Clinical practice guidelines for nutritional assessment and monitoring of adult ICU patients in China by Guan, Xiangdong, Chen, Dechang, Xu, Yuan

“…The Chinese Society of Critical Care Medicine (CSCCM) has developed clinical practice guidelines for nutrition assessment and monitoring for patients in adult…”
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Targeting Selective Autophagy as a Therapeutic Strategy for Viral Infectious Diseases by Liu, Yishan, Zhou, Tao, Hu, Jiajia, Jin, Shouheng, Wu, Jianfeng, Guan, Xiangdong, Wu, Yaoxing, Cui, Jun

“…Autophagy is an evolutionarily conserved lysosomal degradation system which can recycle multiple cytoplasmic components under both physiological and stressful…”
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Molecular mechanisms and cellular functions of liquid-liquid phase separation during antiviral immune responses by Yang, Shuai, Shen, Weishan, Hu, Jiajia, Cai, Sihui, Zhang, Chenqiu, Jin, Shouheng, Guan, Xiangdong, Wu, Jianfeng, Wu, Yaoxing, Cui, Jun

“…Spatiotemporal separation of cellular components is vital to ensure biochemical processes. Membrane-bound organelles such as mitochondria and nuclei play a…”
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Autophagy Activation Induces p62-Dependent Autophagic Degradation of Dengue Virus Capsid Protein During Infection by Wu, Yaoxing, Zhou, Tao, Hu, Jiajia, Liu, Yishan, Jin, Shouheng, Wu, Jianfeng, Guan, Xiangdong, Cui, Jun

“…In the past decade, dengue virus infection is one of the most prevalent and rapidly spreading arthropod-borne diseases worldwide with about 400 million…”
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Heparin-binding protein as a biomarker for the diagnosis of sepsis in the intensive care unit: a retrospective cross-sectional study in China by Zuo, Lingyun, Li, Xiaoyun, Wang, Luhao, Yuan, Hao, Liao, Zihuai, Zhou, Si, Wu, Jianfeng, Guan, Xiangdong, Liu, Yongjun

“…ObjectivesThis study aims to investigate the diagnostic value of heparin-binding protein (HBP) in sepsis and develop a sepsis diagnostic model incorporating…”
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Guidelines for the diagnosis, treatment, prevention and control of infections caused by carbapenem-resistant gram-negative bacilli by Zeng, Mei, Xia, Jun, Zong, Zhiyong, Shi, Yi, Ni, Yuxing, Hu, Fupin, Chen, Yijian, Zhuo, Chao, Hu, Bijie, Lv, Xiaoju, Li, Jiabin, Liu, Zhengyin, Zhang, Jing, Yang, Wenjie, Yang, Fan, Yang, Qiwen, Zhou, Hua, Li, Xin, Wang, Jianhua, Li, Yimin, Ren, Jian'an, Chen, Baiyi, Chen, Dechang, Wu, Anhua, Guan, Xiangdong, Qu, Jieming, Wu, Depei, Huang, Xiaojun, Qiu, Haibo, Xu, Yingchun, Yu, Yunsong, Wang, Minggui

“…The dissemination of carbapenem-resistant Gram-negative bacilli (CRGNB) is a global public health issue. CRGNB isolates are usually extensively drug-resistant…”
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The Current Epidemiological Landscape of Ventilator-associated Pneumonia in the Intensive Care Unit: A Multicenter Prospective Observational Study in China by Xie, Jianfeng, Yang, Yi, Huang, Yingzi, Kang, Yan, Xu, Yuan, Ma, Xiaochun, Wang, Xue, Liu, Jian, Wu, Dawei, Tang, Yaoqing, Qin, Bingyu, Guan, Xiangdong, Li, Jianguo, Yu, Kaijiang, Liu, Dawei, Yan, Jing, Qiu, Haibo

“…Abstract Background Ventilator-associated pneumonia (VAP) is among the most important hospital-acquired infections in the intensive-care unit setting. However,…”
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Increased body mass index linked to greater short- and long-term survival in sepsis patients: A retrospective analysis of a large clinical database by Li, Shuhe, Hu, Xiaoguang, Xu, Jinghong, Huang, Fa, Guo, Zilu, Tong, Li, Lui, Ka Yin, Cao, Lu, Zhu, Yanping, Yao, Jiyou, Lin, Xiaobin, Guan, Xiangdong, Cai, Changjie

“…•Overweight and obese patients had greater survival benefits at 30 days and 1year.•Underweight patients tended to have higher mortality risk.•Obese patients…”
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Early sedation using ciprofol for intensive care unit patients requiring mechanical ventilation: a pooled post-hoc analysis of data from phase 2 and phase 3 trials by Liu, Yongjun, Zuo, Lingyun, Li, Xiaoyun, Nie, Yao, Chen, Chuanxi, Liu, Ning, Chen, Minying, Wu, Jianfeng, Guan, Xiangdong

“…Background Ciprofol was approved for use in intensive care unit (ICU) patients requiring sedation during mechanical ventilation in July 2022. A pooled post-hoc…”
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Chinese critical care certified course in intensive care unit: a nationwide-based analysis by Li, Li, Xu, Qianghong, Cai, Guolong, Gong, Shijin, Liu, Dawei, Qiu, Haibo, Yu, Kaijiang, Chen, Dechang, Guan, Xiangdong, Yan, Jing

“…Abstract Background A training program for intensive care unit (ICU) physicians entitled “Chinese Critical Care Certified Course” (5 C) started in China in…”
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Expert consensus on the diagnosis and treatment of severe and critical coronavirus disease 2019 by Shang, You, Wu, Jianfeng, Liu, Jinglun, Long, Yun, Xie, Jianfeng, Zhang, Dong, Hu, Bo, Zong, Yuan, Liao, Xuelian, Shang, Xiuling, Ding, Renyu, Kang, Kai, Liu, Jiao, Pan, Aijun, Xu, Yonghao, Wang, Changsong, Xu, Qianghong, Zhang, Xijing, Zhang, Jicheng, Liu, Ling, Zhang, Jiancheng, Yang, Yi, Yu, Kaijiang, Guan, Xiangdong, Chen, Dechang

“…[1–3] To better standardize and guide the diagnosis and treatment of severe and critical COVID-19 patients and improve the treatment success rate, the…”
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Phase-separated nucleocapsid protein of SARS-CoV-2 suppresses cGAS-DNA recognition by disrupting cGAS-G3BP1 complex by Cai, Sihui, Zhang, Chenqiu, Zhuang, Zhen, Zhang, Shengnan, Ma, Ling, Yang, Shuai, Zhou, Tao, Wang, Zheyu, Xie, Weihong, Jin, Shouheng, Zhao, Jincun, Guan, Xiangdong, Wu, Jianfeng, Cui, Jun, Wu, Yaoxing

“…Currently, the incidence and fatality rate of SARS-CoV-2 remain continually high worldwide. COVID-19 patients infected with SARS-CoV-2 exhibited decreased type…”
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Design, synthesis and 3D-QSAR of β-carboline derivatives as potent antitumor agents by Cao, Rihui, Guan, Xiangdong, Shi, Buxi, Chen, Zhiyong, Ren, Zhenhua, Peng, Wenlie, Song, Huacan

“…In a continuing effort to develop novel β-carbolines endowed with better pharmacological profiles, a series of β-carboline derivatives were designed and…”
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