Search Results - "Xiang, Zhichu"
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A Multivariate‐Gated DNA Nanodevice for Spatioselective Imaging of Pro‐metastatic Targets in Extracellular Microenvironment
Published in Angewandte Chemie International Edition (21-01-2022)“…Probing pro‐metastatic biomarkers is of significant importance to evaluate the risk of tumor metastasis, but spatially selective imaging of such targets in…”
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Peptide Nucleic Acid (PNA)‐Guided Peptide Engineering of an Aptamer Sensor for Protease‐Triggered Molecular Imaging
Published in Angewandte Chemie International Edition (11-10-2021)“…Protease‐triggered control of functional DNA has remained unachieved, leaving a significant gap in activatable DNA biotechnology. Herein, we report the design…”
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3
Coordination-driven assembly of proteins and nucleic acids in a single architecture for carrier-free intracellular co-delivery
Published in Nano today (01-06-2021)“…•We reported an extremely simple approach to produce a hybrid platform for the intracellular co-delivery of protein and nucleic acid therapeutics.•This system…”
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Drug-internalized bacterial swimmers for magnetically manipulable tumor-targeted drug delivery
Published in Nanoscale (02-07-2020)“…Tumor-targeted drug carriers are becoming attractive for precise drug delivery in anti-tumor therapy. However, a lot of the reported drug delivery systems are…”
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Self‐Confirming Magnetosomes for Tumor‐Targeted T1/T2 Dual‐Mode MRI and MRI‐Guided Photothermal Therapy
Published in Advanced healthcare materials (01-07-2022)“…Nanomaterials as T1/T2 dual‐mode magnetic resonance imaging (MRI) contrast agents have great potential in improving the accuracy of tumor diagnosis…”
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Frontispiece: A Multivariate‐Gated DNA Nanodevice for Spatioselective Imaging of Pro‐metastatic Targets in Extracellular Microenvironment
Published in Angewandte Chemie International Edition (21-01-2022)“…DNA Nanodevices In their Communication (e202111836), Jun Song, Lele Li et al. report a multivariate‐gated DNA nanodevice for spatioselective imaging of…”
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Engineering magnetotactic bacteria MVs to synergize chemotherapy, ferroptosis and immunotherapy for augmented antitumor therapy
Published in Nanoscale horizons (24-07-2023)“…One main obstacle to targeted cancer therapies is the immunosuppressive tumor microenvironment, which can facilitate tumor growth and induce resistance to…”
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Peptide probes derived from pertuzumab by molecular dynamics modeling for HER2 positive tumor imaging
Published in PLoS computational biology (01-04-2017)“…A high level of HER2 expression in breast cancer correlates with a higher tumor growth rate, high metastatic potential, and a poor long-term patient survival…”
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9
Stimuli-Responsive Polymeric Nanosystems for Controlled Drug Delivery
Published in Applied sciences (01-10-2021)“…Biocompatible nanosystems based on polymeric materials are promising drug delivery nanocarrier candidates for antitumor therapy. However, the efficacy is…”
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10
Engineering of a DNA/γPNA Hybrid Nanoreporter for ctDNA Mutation Detection via γPNA Urinalysis
Published in Advanced science (01-09-2024)“…Detection of circulating tumor DNA (ctDNA) mutations, which are molecular biomarkers present in bodily fluids of cancer patients, can be applied for tumor…”
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Frontispiz: A Multivariate‐Gated DNA Nanodevice for Spatioselective Imaging of Pro‐metastatic Targets in Extracellular Microenvironment
Published in Angewandte Chemie (21-01-2022)“…DNA‐Nanofunktionseinheiten In ihrer Zuschrift (e202111836) berichten Jun Song, Lele Li et al. über eine multivariate DNA‐Nanofunktionseinheit für die…”
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12
A Multivariate‐Gated DNA Nanodevice for Spatioselective Imaging of Pro‐metastatic Targets in Extracellular Microenvironment
Published in Angewandte Chemie (21-01-2022)“…Probing pro‐metastatic biomarkers is of significant importance to evaluate the risk of tumor metastasis, but spatially selective imaging of such targets in…”
Get full text
Journal Article -
13
Peptide Nucleic Acid (PNA)‐Guided Peptide Engineering of an Aptamer Sensor for Protease‐Triggered Molecular Imaging
Published in Angewandte Chemie (11-10-2021)“…Protease‐triggered control of functional DNA has remained unachieved, leaving a significant gap in activatable DNA biotechnology. Herein, we report the design…”
Get full text
Journal Article -
14
HER2 Targeting Peptides Screening and Applications in Tumor Imaging and Drug Delivery
Published in Theranostics (01-01-2016)“…Herein, computational-aided one-bead-one-compound (OBOC) peptide library design combined with in situ single-bead sequencing microarray methods were…”
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Peptosome Coadministration Improves Nanoparticle Delivery to Tumors through NRP1-Mediated Co-Endocytosis
Published in Biomolecules (Basel, Switzerland) (05-05-2019)“…Improving the efficacy of nanoparticles (NPs) delivery to tumors is critical for cancer diagnosis and therapy. In our previous work, amphiphilic peptide APPA…”
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Tumor detection using magnetosome nanoparticles functionalized with a newly screened EGFR/HER2 targeting peptide
Published in Biomaterials (01-01-2017)“…Abstract A novel peptide (P75) targeting EGFR and HER2 is successfully screened from a one-bead-one-compound (OBOC) library containing approximately 2 × 105…”
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CD151 enrichment in exosomes of luminal androgen receptor breast cancer cell line contributes to cell invasion
Published in Biochimie (01-10-2021)“…Breast cancer is the most common and highly heterogeneous disease in women worldwide. Given the challenges in the treatment of advanced metastatic breast…”
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18
Self‐Confirming Magnetosomes for Tumor‐Targeted T 1 /T 2 Dual‐Mode MRI and MRI‐Guided Photothermal Therapy
Published in Advanced healthcare materials (01-07-2022)“…Abstract Nanomaterials as T 1 / T 2 dual‐mode magnetic resonance imaging (MRI) contrast agents have great potential in improving the accuracy of tumor…”
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19
Programming peptide-oligonucleotide nano-assembly for engineering of neoantigen vaccine with potent immunogenicity
Published in Theranostics (01-01-2024)“…Neoantigen nanovaccine has been recognized as a promising treatment modality for personalized cancer immunotherapy. However, most current nanovaccines are…”
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20
Self-Confirming Magnetosomes for Tumor-targeted T 1 /T 2 Dual-Mode MR Imaging and MRI-Guided Photothermal Therapy
Published in Advanced healthcare materials (17-05-2022)“…Nanomaterials as T /T dual-mode magnetic resonance imaging (MRI) contrast agents have great potential in improving the accuracy of tumor diagnosis…”
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