Search Results - "Xiang, Yuejun"

Synthesis of Dihydroisoxazole Nucleoside and Nucleotide Analogs by Gi, Hung-Jang, Xiang, Yuejun, Schinazi, Raymond F, Zhao, Kang

“…The dihydroisoxazole nucleosides as well as their phosphonate derivatives were efficiently prepared via 1,3-dipolar cycloaddition reactions of nitrile oxides…”
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Structure−Activity Relationships of 2‘-Deoxy-2‘,2‘-difluoro-l-erythro-pentofuranosyl Nucleosides by Kotra, Lakshmi P, Xiang, Yuejun, Newton, M. Gary, Schinazi, Raymond F, Cheng, Yung-C, Chu, Chung K

“…Following the recent discoveries that some l-nucleosides are more or equal potent than their d-counterparts, we synthesized…”
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Synthesis and anti-HIV activity of dihydroisoxazole 6-chloropurine and adenine by Yuejun Xiang, Jie Chen, Schinazi, Raymond F, Kang Zhao

“…Dihydroisoxazole 6-chloropurine and adenine were efficiently prepared via 1,3-dipolar cycloaddition reaction of a nitrile oxide with vinyl 6-chloropurine, and…”
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N-O diheterocyclic nucleosides: Synthesis of 2′- n-methyl-3′-hydroxymethyl-1′,2′-isoxazolidinylthymidine by Xiang, Yuejun, Chen, Jie, Schinazi, Raymond F., Zhao, Kang

“…Isoxazolidine thymidine derivatives were synthesized by the condensation of silylated thymine with isoxazolidinyl acetate prepared by the Michael addition of…”
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Synthesis of [3.3.0] bicyclic isoxazolidinyl nucleosides by Xiang, Yuejun, Schinazi, Raymond F., Zhao, Kang

“…The isoxazolidine derivative 6, prepared from an intermolecular 1,3-dipolar cycloaddition of the (5 S)-unsaturated lactone 5 and N-methylnitrone, was…”
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Enantioselective synthesis of isoxazolidinyl thymine and cytosine nucleoides by Xiang, Yuejun, Gong, Youxiang, Zhao, Kang

“…A diastereo- and enantioselective synthesis of isoxazolidinyl nucleosides ( 4) is described. The required isoxazolidine intermediate ( 16) was successfully…”
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A live-cell fluorescence microplate assay suitable for monitoring vacuolation arising from drug or toxic agent treatment by Coleman, Jack, Xiang, Yuejun, Pande, Praveen, Shen, Dee, Gatica, Divina, Patton, Wayne F

“…Lysosomes are membrane-bound subcellular organelles involved in the degradation of macromolecules and pathogens in diverse processes, including endocytosis,…”
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Organelle‐targeting, red‐emitting fluorescent probes with superior photo‐physical properties for multiplexing with green fluorescent protein (GFP) in live cells by Coleman, Jack, Xiang, Yuejun, Shen, Dee, Pande, Praveen, Schwartz, Geoffrey, Gattica, Divina, Patton, Wayne

“…Abstract only Cell‐based assays are increasingly gaining in popularity in the biotechnology and pharmaceutical industry due to their high physiological…”
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A cell-permeant dye for cell cycle analysis by flow and laser-scanning microplate cytometry by Patton, Wayne F, Xiang, YueJun, Cox, Hilary, Lebedeva, Irina, Coleman, Jack, Shen, Dee, Pande, Praveen, Schultz, Joanne

“…Enzo Life Sciences Nuclear-ID ™ Red DNA stain is useful for staging cells on the basis of their DNA content. The stain can be applied to live,…”
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Use of 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil as a novel antiviral agent for hepatitis B virus and Epstein-Barr virus by CHU, C. K, TIANWEI MA, KIRUPA SHANMUGANATHAN, CHUNGUANG WANG, YUEJUN XIANG, BALAKRISHNA PAI, S, GANG-QING YAO, SOMMADOSSI, J.-P, YUNG-CHI CHENG

“…Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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An Efficient Route to β-d-Isoxazolidinyl Nucleosides via Diastereoselective Michael Addition of Hydroxylamine to Unsaturated Esters by Xiang, Yuejun, Gi, Hung-Jang, Niu, Deqiang, Schinazi, Raymond F, Zhao, Kang

“…Enantioselective syntheses of β-d-isoxazolidinyl pyrimidine and purine nucleosides are described. Michael addition of N-methylhydroxylamine to α,β-unsaturated…”
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Novel C-nucleoside analogs of 1,3-dioxolane: Synthesis of enantiomeric (2′R,4′S)- and (2′S,4′R)-2-[4-(hydroxymethyl)-1,3-dioxolan-2-yl]-1,3-thiazol-4-carboxamide by Xiang, Yuejun, Teng, Quincy, Chu, Chung K.

“…Novel C-nucleosides (2′R,4′S)-and (2′S,4′R)-2-[4-(hydroxymethyl)-1,3-dioxolan-2-yl]-1,3-thiazole-4-carboxamide have been synthesized from stereoselectively…”
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Synthesis and anti-HIV activities of 2′-deoxy-2′,2″-difluoro-β- L-ribofuranosyl-pyrimidine and -purine nucleosides by Yuejun Xiang, Kotra, Lakshmi P., Chu, Chung K., Schinazi, Raymond F.

“…1- or 9-(2-Deoxy-2,2-difluoro-β- L-ribofuranosyl)-thymine, -cytosine and -adenine were synthesized and their in vitro activity against HIV were evaluated. 1-…”
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Anti-human immunodeficiency virus type-1 (HIV-1) and anti-hepatitis B virus (HBV) activities of (2,3-dideoxy-2-fluoro- β- L- threo-pentofuranosyl)nucleosides by Xiang, Yuejun, Cavalcanti, Socrates, Chu, Chung K., Schinazi, Raymond F., Balakrishna Pai, S., Young-Lian Zhu, Yung-Chi Cheng

“…1-or-9-(2,3-Dideoxy-2-fluoro- β- L- threo-pentofuranosyl)- cytosine (F- β- L-ara-ddC) and-adenine (F- β- L-ara-ddA) were synthesized and their anti-HIV and…”
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Synthesis of 2',3'-dideoxy-2'-fluoro-L-threo-pentofuranosyl nucleosides as potential antiviral agents by Cavalcanti, S C, Xiang, Y, Newton, M G, Schinazi, R F, Cheng, Y C, Chu, C K

“…A series of 2',3'-dideoxy-2'-fluoro-L-threo-pentofuranosyl nucleosides has been synthesized as potential antiviral agents. The synthesized compounds were…”
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