Search Results - "Xiang, Mingli"

Bio-inspired detoxification using 3D-printed hydrogel nanocomposites by Gou, Maling, Qu, Xin, Zhu, Wei, Xiang, Mingli, Yang, Jun, Zhang, Kang, Wei, Yuquan, Chen, Shaochen

“…Rationally designed nanoparticles that can bind toxins show great promise for detoxification. However, the conventional intravenous administration of…”
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Improving antiangiogenesis and anti-tumor activity of curcumin by biodegradable polymeric micelles by Gong, Changyang, Deng, Senyi, Wu, Qinjie, Xiang, Mingli, Wei, Xiawei, Li, Ling, Gao, Xiang, Wang, Bilan, Sun, Lu, Chen, Yishan, Li, Yuchen, Liu, Lei, Qian, Zhiyong, Wei, Yuquan

“…Abstract For developing aqueous formulation and improving anti-tumor activity of curcumin (Cur), we prepared Cur encapsulated MPEG-PCL micelles by solid…”
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Metformin prevents against oxidative stress-induced senescence in human periodontal ligament cells by Kuang, Yunchun, Hu, Bo, Feng, Ge, Xiang, Mingli, Deng, Yuejia, Tan, Minmin, Li, Jie, Song, Jinlin

“…Periodontitis is a chronic infectious disease involving periodontal tissues. Periodontal ligament cells (PDLCs) play an important role in the regeneration of…”
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Metformin enhances the therapeutic effects of extracellular vesicles derived from human periodontal ligament stem cells on periodontitis by Xiang, Mingli, Liu, Yulin, Guo, Qiushuang, Liao, Chengcheng, Xiao, Linlin, Xiang, Meiling, Guan, Xiaoyan, Liu, Jianguo

“…Metformin has shown outstanding anti-inflammatory and osteogenic abilities. Mesenchymal stem cell-derived extracellular vesicles (EVs) reveal promising…”
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The Biological Significance of AFF4: Promoting Transcription Elongation, Osteogenic Differentiation and Tumor Progression by Long, Qian, Xiang, Mingli, Xiao, Linlin, Wang, Jiajia, Guan, Xiaoyan, Liu, Jianguo, Liao, Chengcheng

“…As a member of the AF4/FMR2 (AFF) family, AFF4 is a scaffold protein in the superelongation complex (SEC). In this mini-view, we discuss the role of AFF4 as a…”
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B7 family protein glycosylation: Promising novel targets in tumor treatment by Xiao, Linlin, Guan, Xiaoyan, Xiang, Mingli, Wang, Qian, Long, Qian, Yue, Chaoyi, Chen, Lulu, Liu, Jianguo, Liao, Chengcheng

“…Cancer immunotherapy, including the inhibition of immune checkpoints, improves the tumor immune microenvironment and is an effective tool for cancer therapy…”
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Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents by Wang, Guangcheng, Li, Chunyan, He, Lin, Lei, Kai, Wang, Fang, Pu, Yuzi, Yang, Zhuang, Cao, Dong, Ma, Liang, Chen, Jinying, Sang, Yun, Liang, Xiaolin, Xiang, Mingli, Peng, Aihua, Wei, Yuquan, Chen, Lijuan

“…A new series of pyrano chalcone derivatives containing indole moiety were synthesized and evaluated for their antiproliferative activities. Among these…”
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LIPUS promotes FOXO1 accumulation by downregulating miR-182 to enhance osteogenic differentiation in hPDLCs by Chen, Duanjing, Xiang, Mingli, Gong, Yuanyuan, Xu, Ling, Zhang, Tingwei, He, Yao, Zhou, Mengjiao, Xin, Liangjing, Li, Jie, Song, Jinlin

“…Low intensity pulsed ultrasound (LIPUS) promotes bone fracture healing in clinical therapy. Transcription factor Forkhead box O1 (FOXO1) is crucial for bone…”
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Summer Thermal Challenges in Emergency Tents: Insights into Thermal Characteristics of Tents with Air Conditioning by Xiang, Mingli, Liao, Yuxuan, Jia, Yonghong, Zhang, Wentao, Long, Enshen

“…Emergency tents face challenges in harsh weather conditions and sometimes require the use of air conditioning for indoor thermal environment control. However,…”
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Effect of chewing gum on orthodontic pain in patients receiving fixed orthodontic treatment: a systematic review and meta-analysis by Guo, Qiushuang, Liao, Chengcheng, Guan, Xiaoyan, Xiao, Linlin, Xiang, Meiling, Long, Sicen, Liu, Jianguo, Xiang, Mingli

“…Abstract Objectives The objective of this systematic review and meta-analysis was to evaluate the effect of chewing gum on orthodontic pain and to determine…”
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Applying an innovative biodegradable self-assembly nanomicelles to deliver α-mangostin for improving anti-melanoma activity by Yang, Shuping, Gao, Xiang, He, Yihong, Hu, Yuzhu, Xu, Bocheng, Cheng, Zhiqiang, Xiang, Mingli, Xie, Yongmei

“…α-Mangostin (αM), a traditional natural product with promising application of treating a series of diseases, was limited use in clinical due to its…”
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Dynamic Heat Transfer Calculation for Ground-Coupled Floor in Emergency Temporary Housing by Ding, Pei, Li, Jin, Xiang, Mingli, Cheng, Zhu, Long, Enshen

“…Generally, ground-coupled floor heat transfer is supposed as annual periodic, which is reasonable for conventional buildings. However, for emergency housing…”
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Computer-aided drug design: lead discovery and optimization by Xiang, Mingli, Cao, Yu, Fan, Wenjie, Chen, Lijuan, Mo, Yirong

“…Over the past decade, there have been remarkable advances in the area of computer-aided drug design (CADD), which has been applied at almost all stages in the…”
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SKLB023 blocks joint inflammation and cartilage destruction in arthritis models via suppression of nuclear factor-kappa B activation in macrophage by Xie, Caifeng, Ma, Liang, Liu, Juan, Li, Xiuxia, Pei, Heying, Xiang, Mingli, Chen, Lijuan

“…Rheumatoid arthritis (RA) is the most common arthritis and is mainly characterized by symmetric polyarticular joint disorders. Our previous study demonstrated…”
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First-principles study of the adsorption of lysine on hydroxyapatite (100) surface by Lou, Zhaoyang, Zeng, Qun, Chu, Xiang, Yang, Fang, He, Duanwei, Yang, Mingli, Xiang, Mingli, Zhang, Xingdong, Fan, Hongsong

“…[Display omitted] ► Conformers of Lys on HA (100) surface are identified. ► Multiple interactions that favor the Lys adsorption are revealed. ► Strong ionic…”
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Design, synthesis and biological evaluation of thiazole- and indole-based derivatives for the treatment of type II diabetes by Xu, Qinyuan, Huang, Li, Liu, Juan, Ma, Liang, Chen, Tao, Chen, Jinying, Peng, Fei, Cao, Dong, Yang, Zhuang, Qiu, Neng, Qiu, Jingxiang, Wang, Guangcheng, Liang, Xiaolin, Peng, Aihua, Xiang, Mingli, Wei, Yuquan, Chen, Lijuan

“…Present studies have shown that the lipid carrier has a significant role in several aspects of metabolic syndrome in A-FABP/ap2-deficient mice, including type…”
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Discovery of novel focal adhesion kinase inhibitors using a hybrid protocol of virtual screening approach based on multicomplex-based pharmacophore and molecular docking by Wu, Fengbo, Xu, Ting, He, Gu, Ouyang, Liang, Han, Bo, Peng, Cheng, Song, Xiangrong, Xiang, Mingli

“…Focal adhesion kinase (FAK) is a tyrosine kinase that functions as a key orchestrator of signals leading to invasion and metastasis. In the current study, the…”
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Combined structure-based pharmacophore and 3D-QSAR studies on phenylalanine series compounds as TPH1 inhibitors by Ouyang, Liang, He, Gu, Huang, Wei, Song, Xiangrong, Wu, Fengbo, Xiang, Mingli

“…Tryptophan hydroxylase-1 (TPH1) is a key enzyme in the synthesis of serotonin. As a neurotransmitter, serotonin plays important physiological roles both…”
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A novel agonist of PPAR-γ based on barbituric acid alleviates the development of non-alcoholic fatty liver disease by regulating adipocytokine expression and preventing insulin resistance by Zheng, Hao, Li, Shilin, Ma, Liang, Cheng, Ling, Deng, Chongyang, Chen, Zhizhi, Xie, Caifeng, Xiang, Mingli, Jiang, Wei, Chen, Lijuan

“…Non-alcoholic fatty liver disease (NAFLD) is a frequent kind of metabolic syndrome, which included a wide spectrum of liver damage and closely associated with…”
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Rational design, synthesis, and pharmacological properties of pyranochalcone derivatives as potent anti-inflammatory agents by Peng, Fei, Wang, Guangcheng, Li, Xiuxia, Cao, Dong, Yang, Zhuang, Ma, Liang, Ye, Haoyu, Liang, Xiaolin, Ran, Yan, Chen, Jinying, Qiu, Jingxiang, Xie, Caifeng, Deng, Chongyang, Xiang, Mingli, Peng, Aihua, Wei, Yuquan, Chen, Lijuan

“…24 derivatives (5a–x) derived from natural pyranochalcones (I and II) were designed and evaluated for their inhibitory potency on the production of nitric…”
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