Effects of high-intensity interval training on physical morphology, cardiorespiratory fitness and metabolic risk factors of cardiovascular disease in children and adolescents: A systematic review and meta-analysis

To systematically evaluate the safety and efficacy of high-intensity interval training in children and adolescents. Eight databases were searched. Descriptive analysis of the efficacy and safety of high-intensity interval training on body shape, cardiorespiratory fitness, and metabolic risk markers...

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Bibliographic Details
Published in:	PloS one Vol. 18; no. 5; p. e0271845
Main Authors:	Men, Jie, Zou, Shuangling, Ma, Jia, Xiang, Chenmin, Li, Shufeng, Wang, Junli
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 11-05-2023 Public Library of Science (PLoS)
Subjects:	Adolescent Adolescents Aerobics Anaerobic threshold Bias Biology and Life Sciences Biomarkers Body composition Cardiorespiratory Fitness Cardiovascular disease Cardiovascular diseases Cardiovascular Diseases - prevention & control Child Children Children & youth Clinical trials Demographic aspects Diseases Effectiveness Energy consumption Evaluation Exercise Fitness Health aspects Health risks Health surveys High density lipoprotein High-Intensity Interval Training Humans Indicators Interval training Intervention Low density lipoprotein Low density lipoproteins Medical research Medicine and Health Sciences Meta-analysis Metabolism Morphology Obesity Oxygen consumption Pediatric cardiology People and Places Performance evaluation Physical Fitness Physical Sciences Physical training Research and Analysis Methods Risk Factors Safety Sensitivity analysis Shape effects Subgroups Supervision Systematic review Teenagers Training Youth China
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Summary:	To systematically evaluate the safety and efficacy of high-intensity interval training in children and adolescents. Eight databases were searched. Descriptive analysis of the efficacy and safety of high-intensity interval training on body shape, cardiorespiratory fitness, and metabolic risk markers of cardiovascular disease in children and adolescents. Subgroup analysis was performed using age, participants, intervention time, and exercise frequency as covariates. 47 studies included 2995 children and adolescents. The results of the meta-analysis showed that high-intensity interval training significantly improved cardiorespiratory fitness indicators (VO2max, SBP, DBP and HRmax) and cardiovascular disease biomarkers (TC and HDL-C). HIIT had no significant effect on body shape indicators (BMI, BF% and WC) or cardiovascular disease biomarkers (TG and LDL-C). Currently, there is insufficient evidence that HIIT with interval running as the predominant form improves physical indicators in children and adolescents. However, HIIT can be promoted in children and adolescents to improve cardiorespiratory fitness and reduce some metabolic risk of cardiovascular disease.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Undefined-3 JM and SZ are co-first authors and contributed equally to this work. Competing Interests: The authors have declared that no competing interests exist.
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0271845