Search Results - "Xiang, Chengang"

Long-term functional maintenance of primary human hepatocytes in vitro by Xiang, Chengang, Du, Yuanyuan, Meng, Gaofan, Soon Yi, Liew, Sun, Shicheng, Song, Nan, Zhang, Xiaonan, Xiao, Yiwei, Wang, Jie, Yi, Zhigang, Liu, Yifang, Xie, Bingqing, Wu, Min, Shu, Jun, Sun, Da, Jia, Jun, Liang, Zhen, Sun, Dong, Huang, Yanxiang, Shi, Yan, Xu, Jun, Lu, Fengmin, Li, Cheng, Xiang, Kuanhui, Yuan, Zhenghong, Lu, Shichun, Deng, Hongkui

“…The maintenance of terminally differentiated cells, especially hepatocytes, in vitro has proven challenging. Here we demonstrated the long-term in vitro…”
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Hepatic spheroids derived from human induced pluripotent stem cells in bio-artificial liver rescue porcine acute liver failure by Chen, Sitong, Wang, Jinglin, Ren, Haozhen, Liu, Yinan, Xiang, Chengang, Li, Cheng, Lu, Shichun, Shi, Yan, Deng, Hongkui, Shi, Xiaolei

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Single Cell RNA Sequencing Identifies a Unique Inflammatory Macrophage Subset as a Druggable Target for Alleviating Acute Kidney Injury by Yao, Weijian, Chen, Ying, Li, Zehua, Ji, Jing, You, Abin, Jin, Shanzhao, Ma, Yuan, Zhao, Youlu, Wang, Jinwei, Qu, Lei, Wang, Hui, Xiang, Chengang, Wang, Suxia, Liu, Gang, Bai, Fan, Yang, Li

“…Acute kidney injury (AKI) is a complex clinical disorder associated with poor outcomes. Targeted regulation of the degree of inflammation has been a potential…”
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Generation of Naive Induced Pluripotent Stem Cells from Rhesus Monkey Fibroblasts by Fang, Riguo, Liu, Kang, Zhao, Yang, Li, Haibo, Zhu, Dicong, Du, Yuanyuan, Xiang, Chengang, Li, Xiang, Liu, Haisong, Miao, Zhenchuan, Zhang, Xing, Shi, Yan, Yang, Weifeng, Xu, Jun, Deng, Hongkui

“…Conventional embryonic stem cells (ESCs) or induced pluripotent stem cells (iPSCs) derived from primates resemble mouse epiblast stem cells, raising an…”
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Two supporting factors greatly improve the efficiency of human iPSC generation by Zhao, Yang, Yin, Xiaolei, Qin, Han, Zhu, Fangfang, Liu, Haisong, Yang, Weifeng, Zhang, Qiang, Xiang, Chengang, Hou, Pingping, Song, Zhihua, Liu, Yanxia, Yong, Jun, Zhang, Pengbo, Cai, Jun, Liu, Meng, Li, Honggang, Li, Yanqin, Qu, Xiuxia, Cui, Kai, Zhang, Weiqi, Xiang, Tingting, Wu, Yetao, Zhao, Yiding, Liu, Chun, Yu, Chen, Yuan, Kehu, Lou, Jinning, Ding, Mingxiao, Deng, Hongkui

“…Human fibroblasts can be induced into pluripotent stem cells (iPSCs), but the reprogramming efficiency is quite low. Here, we screened a panel of candidate…”
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A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts by Xie, Bingqing, Sun, Da, Du, Yuanyuan, Jia, Jun, Sun, Shicheng, Xu, Jun, Liu, Yifang, Xiang, Chengang, Chen, Sitong, Xie, Huangfan, Wang, Qiming, Li, Guangya, LYU, Xuehui, Shen, Hui, Li, Shiyu, Wu, Min, Zhang, Xiaonan, Pu, Yue, Xiang, Kuanhui, Lai, Weifeng, Du, Peng, Yuan, Zhenghong, Li, Cheng, Shi, Yan, Lu, Shichun, Deng, Hongkui

“…Terminally differentiated cells can be generated by lineage reprogramming, which is, however, hindered by incomplete conversion with residual initial cell…”
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Promotion of the efficient metabolic maturation of human pluripotent stem cell-derived hepatocytes by correcting specification defects by Zhao, Dongxin, Chen, Song, Duo, Shuguang, Xiang, Chengang, Jia, Jun, Guo, Mina, Lai, Wei, Lu, Shichun, Deng, Hongkui

“…Promoting the functional maturation of the desired cell types derived from human pluripotent stem cells （hPSCs） remains a major challenge, especially for…”
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Human Amniotic Epithelial Cells and Their Derived Exosomes Protect Against Cisplatin-Induced Acute Kidney Injury Without Compromising Its Antitumor Activity in Mice by Kang, Xin, Chen, Ying, Xin, Xiaohong, Liu, Menghan, Ma, Yuan, Ren, Yifei, Ji, Jing, Yu, Qi, Qu, Lei, Wang, Suxia, Liu, Gang, Xiang, Chengang, Yang, Li

“…Cisplatin is a widely used chemotherapeutic drug, whereas the clinical application is greatly limited by its nephrotoxic side effect. Currently, there has been…”
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Nephropathy Is Aggravated by Fatty Acids in Diabetic Kidney Disease through Tubular Epithelial Cell Necroptosis and Is Alleviated by an RIPK-1 Inhibitor by Yu, Qi, Chen, Ying, Zhao, Youlu, Huang, Shuo, Xin, Xiaohong, Jiang, Lei, Wang, Hui, Wu, Wenyan, Qu, Lei, Xiang, Chengang, Wang, Suxia, Liu, Gang, Yang, Li

“…Introduction: Diabetic kidney disease (DKD), one of the leading causes of end-stage renal disease, has complex pathogenic mechanisms and few effective clinical…”
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Human Amnion Epithelial Cells and Their Derived Exosomes Alleviate Sepsis-Associated Acute Kidney Injury via Mitigating Endothelial Dysfunction by Chi, Dongxuan, Chen, Ying, Xiang, Chengang, Yao, Weijian, Wang, Hui, Zheng, Xizi, Xu, Damin, Li, Nan, Xie, Min, Wang, Suxia, Liu, Gang, Li, Shuangling, Yang, Li

“…Sepsis is characterized by organ dysfunction resulting from a patient's dysregulated response to infection. Sepsis-associated acute kidney injury (S-AKI) is…”
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Human Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming by Du, Yuanyuan, Wang, Jinlin, Jia, Jun, Song, Nan, Xiang, Chengang, Xu, Jun, Hou, Zhiyuan, Su, Xiaohua, Liu, Bei, Jiang, Tao, Zhao, Dongxin, Sun, Yingli, Shu, Jian, Guo, Qingliang, Yin, Ming, Sun, Da, Lu, Shichun, Shi, Yan, Deng, Hongkui

“…Obtaining fully functional cell types is a major challenge for drug discovery and regenerative medicine. Currently, a fundamental solution to this key problem…”
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TRIM56 impairs HBV infection and replication by inhibiting HBV core promoter activity by Tian, Xing, Dong, Huijun, Lai, Xinyuan, Ou, Guomin, Cao, Junning, Shi, Jihang, Xiang, Chengang, Wang, Lei, Zhang, Xuechao, Zhang, Kai, Song, Ji, Deng, Juan, Deng, Hongkui, Lu, Shichun, Zhuang, Hui, Li, Tong, Xiang, Kuanhui

“…Members of the tripartite motif (TRIM) protein family strongly induced by interferons (IFNs) are parts of the innate immune system with antiviral activity…”
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Generation of functionally competent hepatic stellate cells from human stem cells to model liver fibrosis in vitro by Lai, Xinyuan, Li, Chuanyun, Xiang, Chengang, Pan, Zihang, Zhang, Kai, Wang, Lei, Xie, Bingqing, Cao, Junning, Shi, Jihang, Deng, Juan, Lu, Shichun, Deng, Hongkui, Zhuang, Hui, Li, Tong, Shi, Yan, Xiang, Kuanhui

“…The detailed understanding of fibrogenesis has been hampered by a lack of important functional quiescence characteristics and an in vitro model to recapitulate…”
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Single Cell RNA Sequencing Identifies a Unique Inflammatory Macrophage Subset as a Druggable Target for Alleviating Acute Kidney Injury (Adv. Sci. 12/2022) by Yao, Weijian, Chen, Ying, Li, Zehua, Ji, Jing, You, Abin, Jin, Shanzhao, Ma, Yuan, Zhao, Youlu, Wang, Jinwei, Qu, Lei, Wang, Hui, Xiang, Chengang, Wang, Suxia, Liu, Gang, Bai, Fan, Yang, Li

“…Alleviating Acute Kidney Injury In article number 2103675, Ying Chen, Fan Bai, Li Yang, and co‐workers revealed S100a8/a9high infiltrated macrophage initiated…”
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Generation of Naive Induced Pluripotent Stem Cells from Rhesus Monkey Fibroblasts by Fang, Riguo, Liu, Kang, Zhao, Yang, Li, Haibo, Zhu, Dicong, Du, Yuanyuan, Xiang, Chengang, Li, Xiang, Liu, Haisong, Miao, Zhenchuan, Zhang, Xing, Shi, Yan, Yang, Weifeng, Xu, Jun, Deng, Hongkui

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Single Cell RNA Sequencing Identifies a Unique Inflammatory Macrophage Subset as a Druggable Target for Alleviating Acute Kidney Injury (Adv. Sci. 12/2022) by Yao, Weijian, Chen, Ying, Li, Zehua, Ji, Jing, You, Abin, Jin, Shanzhao, Ma, Yuan, Zhao, Youlu, Wang, Jinwei, Qu, Lei, Wang, Hui, Xiang, Chengang, Wang, Suxia, Liu, Gang, Bai, Fan, Yang, Li

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ROADM节点内阻塞限制下的RWA算法研究 by 王晓玲, 高丽, 沈纲祥

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关于下一代光传输网络的演进和升级的一些思考(特邀) by 沈纲祥

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超低损耗光纤技术的研究现状 by 李泳成, 杨昊, 郭宁宁, 沈一春, 蒋新力, 钱宜刚, 曹珊珊, 刘志忠, 房红莲, 由骁迪, 沈纲祥

“…TN818; 超低损耗光纤被认为是实现400 Gbit/s甚至1…”
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