Search Results - "Xia, Zhong‐yuan"

Lipopolysaccharide (LPS) Aggravates High Glucose- and Hypoxia/Reoxygenation-Induced Injury through Activating ROS-Dependent NLRP3 Inflammasome-Mediated Pyroptosis in H9C2 Cardiomyocytes by Leng, Yan, Lei, Shao-Qing, Ming, Hao, He, Yuhong, Qiu, Zhen, Xia, Zhong-Yuan

“…Diabetes aggravates myocardial ischemia-reperfusion (I/R) injury because of the combination effects of changes in glucose and lipid energy metabolism,…”
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Safety and efficacy of different anesthetic regimens for parturients with COVID-19 undergoing Cesarean delivery: a case series of 17 patients by Chen, Rong, Zhang, Yuan, Huang, Lei, Cheng, Bi-heng, Xia, Zhong-yuan, Meng, Qing-tao

“…Purpose To assess the management and safety of epidural or general anesthesia for Cesarean delivery in parturients with coronavirus disease (COVID-19) and…”
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Clinical characteristics and outcomes of patients undergoing surgeries during the incubation period of COVID-19 infection by Lei, Shaoqing, Jiang, Fang, Su, Wating, Chen, Chang, Chen, Jingli, Mei, Wei, Zhan, Li-Ying, Jia, Yifan, Zhang, Liangqing, Liu, Danyong, Xia, Zhong-Yuan, Xia, Zhengyuan

“…The outbreak of 2019 novel coronavirus disease (COVID-19) in Wuhan, China, has spread rapidly worldwide. In the early stage, we encountered a small but…”
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NLRP3 Inflammasome Activation-Mediated Pyroptosis Aggravates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats by Xia, Zhong-Yuan, Leng, Yan, Meng, Qing-Tao, Liu, Min, Su, Wating, Wu, Yang, Zhao, Bo, Lei, Shao-Qing, Qiu, Zhen, Zhou, Bin

“…The reactive oxygen species- (ROS-) induced nod-like receptor protein-3 (NLRP3) inflammasome triggers sterile inflammatory responses and pyroptosis, which is a…”
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SIRT3 activator honokiol ameliorates surgery/anesthesia‐induced cognitive decline in mice through anti‐oxidative stress and anti‐inflammatory in hippocampus by Ye, Ji‐Shi, Chen, Lei, Lu, Ya‐Yuan, Lei, Shao‐Qing, Peng, Mian, Xia, Zhong‐Yuan

“…Aims Increasing evidence indicates that neuroinflammatory and oxidative stress play two pivotal roles in cognitive impairment after surgery. Honokiol (HNK), as…”
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Long non‐coding RNA MALAT1 functions as a mediator in cardioprotective effects of fentanyl in myocardial ischemia‐reperfusion injury by Zhao, Zhi‐hui, Hao, Wei, Meng, Qing‐tao, Du, Xiao‐bing, Lei, Shao‐qing, Xia, Zhong‐yuan

“…Long non‐coding (lncRNA) MALAT1 can be increased by hypoxia or ischemic limbs. Also, downregulation of MALAT1 contributes to reduction of cardiomyocyte…”
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The Protective Role of Bmal1-Regulated Autophagy Mediated by HDAC3/SIRT1 Pathway in Myocardial Ischemia/Reperfusion Injury of Diabetic Rats by Qiu, Zhen, Ming, Hao, Zhang, Yi, Yu, Yanli, Lei, Shaoqing, Xia, Zhong-yuan

“…Purpose Histone deacetylase 3 (HDAC3) and silent information regulator 1 (SIRT1) are histone deacetylases that regulate important metabolic pathways and play…”
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The Pathway of Let-7a-1/2-3p and HMGB1 Mediated Dexmedetomidine Inhibiting Microglia Activation in Spinal Cord Ischemia-Reperfusion Injury Mice by Ha sen ta na, Nuo, Ming, Meng, Qing-tao, Xia, Zhong-yuan

“…Microglial cell activation after spinal cord ischemia-reperfusion injury (SCIRI) commonly causes the secondary nerve motion function injury. This study aims to…”
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Honokiol-Mediated Mitophagy Ameliorates Postoperative Cognitive Impairment Induced by Surgery/Sevoflurane via Inhibiting the Activation of NLRP3 Inflammasome in the Hippocampus by Peng, Mian, Lei, Shao-Qing, Lu, Yayuan, Chen, Lei, Ye, Jishi, Xia, Zhong-Yuan

“…Background. The potential mechanism of postoperative cognitive impairment is still largely unclear. The activation of NLRP3 inflammasome had been reported to…”
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The endothelial glycocalyx as a potential theriapeutic target in organ injuries by Cao, Rui-Na, Tang, Li, Xia, Zhong-Yuan, Xia, Rui

“…The endothelial glycocalyx (eGC) is a dynamic and multicomponent layer of macromolecules found at the surface of vascular endothelium, which is largely…”
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Nobiletin alleviates myocardial ischemia-reperfusion injury via ferroptosis in rats with type-2 diabetes mellitus by Huang, Qin, Tian, Liqun, Zhang, Yi, Qiu, Zhen, Lei, Shaoqing, Xia, Zhong-Yuan

“…Susceptibility to myocardial ischemia-reperfusion (IR) injury in type-2 diabetes (T2DM) remains disputed, although studies have reported that ferroptosis is…”
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PTEN in prefrontal cortex is essential in regulating depression-like behaviors in mice by Wang, Xiao-Qing, Zhang, Lei, Xia, Zhong-Yuan, Chen, Jia-Yin, Fang, Yiru, Ding, Yu-Qiang

“…Chronic stress is an environmental risk factor for depression and causes neuronal atrophy in the prefrontal cortex (PFC) and other brain regions. It is still…”
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Ischemic postconditioning attenuates acute kidney injury following intestinal ischemia‐reperfusion through Nrf2‐regulated autophagy, anti‐oxidation, and anti‐inflammation in mice by Chen, Rong, Zeng, Zi, Zhang, Yun‐yan, Cao, Chen, Liu, Hui‐min, Li, Wei, Wu, Yang, Xia, Zhong‐yuan, Ma, Daqing, Meng, Qing‐tao

“…Intestinal ischemia‐reperfusion (IIR) often occurs during and following major cardiovascular or gut surgery and causes significant organ including kidney…”
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Hyperglycemia-Induced Oxidative Stress Abrogates Remifentanil Preconditioning-Mediated Cardioprotection in Diabetic Rats by Impairing Caveolin-3-Modulated PI3K/Akt and JAK2/STAT3 Signaling by Irwin, Michael G., Xia, Zhengyuan, Qiao, Shigang, Zhou, Lu, Wang, Yafeng, Xia, Zhong-Yuan, Su, Wating, Lei, Shao-Qing, Zhao, Bo

“…Diabetic hearts are more vulnerable to ischemia/reperfusion (I/R) injury and less responsive to remifentanil preconditioning (RPC), but the underlying…”
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Rev-erbs agonist SR9009 alleviates ischemia-reperfusion injury by heightening endogenous cardioprotection at onset of type-2 diabetes in rats: Down-regulating ferritinophagy/ferroptosis signaling by Huang, Qin, Tian, Liqun, Zhao, Xiaoshuai, Lei, Shaoqing, Zhao, Bo, Qiu, Zhen, Xia, Zhong-Yuan

“…The complex progression of type-2 diabetes (T2DM) results in inconsistent findings on myocardial susceptibility to ischemia-reperfusion (IR). IR injuries in…”
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Inhibition of HDAC3 Ameliorates Cerebral Ischemia Reperfusion Injury in Diabetic Mice In Vivo and In Vitro by Liu, Lian, Gao, Wen-wei, Li, Mei, Zhan, Li-ying, Xia, Zhong-Yuan, Hou, Jia-Bao, Yuan, Quan, Zhao, Bo, Jiang, Meng

“…Background. A substantial increase in histone deacetylase 3 (HDAC3) expression is implicated in the pathological process of diabetes and stroke. However, it is…”
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DJ-1 overexpression restores ischaemic post-conditioning-mediated cardioprotection in diabetic rats: role of autophagy by Zhou, Bin, Lei, Shaoqing, Xue, Rui, Leng, Yan, Xia, Zhengyuan, Xia, Zhong-Yuan

“…IPO (ischaemic post-conditioning) is a promising method of alleviating myocardial IR (ischaemia-reperfusion) injury; however, IPO-mediated cardioprotection is…”
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Role of the hippocampal 5-HT1A receptor-mediated cAMP/PKA signalling pathway in sevoflurane-induced cognitivedysfunction in aged rats by Qiu, Yi, Wang, Ying, Wang, Xiaodong, Wang, Caixia, Xia, Zhong-yuan

“…Objective This study aimed to evaluate the role of the hippocampal 5-hydroxytryptamine-1A (5-HT1A)-mediated cyclic adenosine monophosphate/protein kinase A…”
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Ischemic Postconditioning Alleviates Intestinal Ischemia-Reperfusion Injury by Enhancing Autophagy and Suppressing Oxidative Stress through the Akt/GSK-3β/Nrf2 Pathway in Mice by Hou, Jia-bao, Sun, Tao, Zeng, Zi, Xia, Zhong-Yuan, Meng, Qing-Tao, Tang, Ling-Hua, Leng, Yan, Wu, Yang, Li, Wei, Liu, Huimin, Lan, Jia-nan, Zhang, Yun-yan, Chen, Rong, Sun, Qian

“…Aims. Ischemic postconditioning (IPO) has a strong protective effect against intestinal ischemia-reperfusion (IIR) injury that is partly related to autophagy…”
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Selective inhibition of PKCβ2 improves Caveolin-3/eNOS signaling and attenuates lipopolysaccharide-induced injury by inhibiting autophagy in H9C2 cardiomyocytes by Yang, Zhou, Su, Wating, Zhang, Yuan, Zhou, Lu, Xia, Zhong-yuan, Lei, Shaoqing

“…Lipopolysaccharide (LPS)-induced autophagy is involved in sepsis-associated myocardial injury with increased PKCβ2 activation. We previously found…”
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