Search Results - "Xia, Youli"

Genetic determinants of the molecular portraits of epithelial cancers by Xia, Youli, Fan, Cheng, Hoadley, Katherine A., Parker, Joel S., Perou, Charles M.

“…The ability to characterize and predict tumor phenotypes is crucial to precision medicine. In this study, we present an integrative computational approach…”
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Circulating tumor DNA reveals complex biological features with clinical relevance in metastatic breast cancer by Prat, Aleix, Brasó-Maristany, Fara, Martínez-Sáez, Olga, Sanfeliu, Esther, Xia, Youli, Bellet, Meritxell, Galván, Patricia, Martínez, Débora, Pascual, Tomás, Marín-Aguilera, Mercedes, Rodríguez, Anna, Chic, Nuria, Adamo, Barbara, Paré, Laia, Vidal, Maria, Margelí, Mireia, Ballana, Ester, Gómez-Rey, Marina, Oliveira, Mafalda, Felip, Eudald, Matito, Judit, Sánchez-Bayona, Rodrigo, Suñol, Anna, Saura, Cristina, Ciruelos, Eva, Tolosa, Pablo, Muñoz, Montserrat, González-Farré, Blanca, Villagrasa, Patricia, Parker, Joel S., Perou, Charles M., Vivancos, Ana

“…Liquid biopsy has proven valuable in identifying individual genetic alterations; however, the ability of plasma ctDNA to capture complex tumor phenotypes with…”
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Molecular analysis of TCGA breast cancer histologic types by Thennavan, Aatish, Beca, Francisco, Xia, Youli, Garcia-Recio, Susana, Allison, Kimberly, Collins, Laura C., Tse, Gary M., Chen, Yunn-Yi, Schnitt, Stuart J., Hoadley, Katherine A., Beck, Andrew, Perou, Charles M.

“…Breast cancer is classified into multiple distinct histologic types, and many of the rarer types have limited characterization. Here, we extend The Cancer…”
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Biologically Targeted Photo‐Crosslinkable Nanopatch to Prevent Postsurgical Peritoneal Adhesion by Mi, Yu, Yang, Feifei, Bloomquist, Cameron, Xia, Youli, Sun, Bo, Qi, Yanfei, Wagner, Kyle, Montgomery, Stephanie A., Zhang, Tian, Wang, Andrew Z.

“…Peritoneal adhesion occurs in a majority of patients following abdominal surgery and can result in significant side effects and complications. Current…”
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Nanomedicine: Biologically Targeted Photo‐Crosslinkable Nanopatch to Prevent Postsurgical Peritoneal Adhesion (Adv. Sci. 19/2019) by Mi, Yu, Yang, Feifei, Bloomquist, Cameron, Xia, Youli, Sun, Bo, Qi, Yanfei, Wagner, Kyle, Montgomery, Stephanie A., Zhang, Tian, Wang, Andrew Z.

“…In article number 1900809, Andrew Z. Wang and co‐workers develop a strategy to prevent postsurgical adhesion using a biologically targeted photo‐crosslinkable…”
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Integrated DNA and RNA Sequencing Reveals Drivers of Endocrine Resistance in Estrogen Receptor-Positive Breast Cancer by Xia, Youli, He, Xiaping, Renshaw, Lorna, Martinez-Perez, Carlos, Kay, Charlene, Gray, Mark, Meehan, James, Parker, Joel S, Perou, Charles M, Carey, Lisa A, Dixon, J Michael, Turnbull, Arran

“…Endocrine therapy resistance (ETR) remains the greatest challenge in treating patients with hormone receptor-positive breast cancer. We set out to identify…”
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Abstract P4-05-12: Genetic determinants of the molecular portraits of epithelial cancers by Xia, Youli, Fan, Cheng, Hoadley, Katherine A, Parker, Joel S, Perou, Charles M

“…Background: Tumorigenesis is often driven by multiple types of aberrations in DNA leading to diseases of enormous complexity and heterogeneity. With the effort…”
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Identification of Small Molecules That Induce Therapeutic Levels of Fetal Hemoglobin for Treatment of Sickle Cell Disease By Pairing Machine Learning with High-Resolution Single Cell RNA Sequencing Maps of Adult and Fetal Human Erythropoiesis by Cortes, Mauricio, Monti, Anthony J, Sun, Sunny, Lynch, Orna, Xia, Youli, Lin, Sarah, Malamas, Michael, Steelman, Scott, Krishnamoorthy, Sriram, Stewart, Morag, Tozzo, Effie

“…Induction of fetal hemoglobin (HbF) to treat sickle cell disease (SCD) and beta-thalassemia has been validated as a clinical strategy to ameliorate these…”
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Integrative Genomics Approaches to Identify Genetic Drivers of Human Breast Cancer by Xia, Youli

“…Breast cancer is a heterogeneous disease as revealed by next generation sequencing studies. Intrinsic molecular subtypes defined by gene expression profiles…”
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Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis by Garcia-Recio, Susana, Hinoue, Toshinori, Wheeler, Gregory L, Kelly, Benjamin J, Garrido-Castro, Ana C, Pascual, Tomas, De Cubas, Aguirre A, Xia, Youli, Felsheim, Brooke M, McClure, Marni B, Rajkovic, Andrei, Karaesmen, Ezgi, Smith, Markia A, Fan, Cheng, Ericsson, Paula I Gonzalez, Sanders, Melinda E, Creighton, Chad J, Bowen, Jay, Leraas, Kristen, Burns, Robyn T, Coppens, Sara, Wheless, Amy, Rezk, Salma, Garrett, Amy L, Parker, Joel S, Foy, Kelly K, Shen, Hui, Park, Ben H, Krop, Ian, Anders, Carey, Gastier-Foster, Julie, Rimawi, Mothaffar F, Nanda, Rita, Lin, Nancy U, Isaacs, Claudine, Marcom, P Kelly, Storniolo, Anna Maria, Couch, Fergus J, Chandran, Uma, Davis, Michael, Silverstein, Jonathan, Ropelewski, Alexander, Liu, Minetta C, Hilsenbeck, Susan G, Norton, Larry, Richardson, Andrea L, Symmans, W Fraser, Wolff, Antonio C, Davidson, Nancy E, Carey, Lisa A, Lee, Adrian V, Balko, Justin M, Hoadley, Katherine A, Laird, Peter W, Mardis, Elaine R, King, Tari A, Perou, Charles M

“…The AURORA US Metastasis Project was established with the goal to identify molecular features associated with metastasis. We assayed 55 females with metastatic…”
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Reshaping the Tumor Microenvironment of KRASG12D Pancreatic Ductal Adenocarcinoma with combined SOS1 and MEK Inhibition for Improved Immunotherapy Response by Norgard, Robert J, Budhani, Pratha, O'Brien, Sarah A, Xia, Youli, Egan, Jessica N, Flynn, Brianna, Tagore, Joshua R, Seco, Joseph, Peet, Gregory W, Mikucka, Ania, Wasti, Ruby, Chan, Li-Chuan, Hinkel, Melanie, Martinez-Morilla, Sandra, Pignatelli, Jeanine, Trapani, Francesca, Corse, Emily, Feng, Di, Kostyrko, Kaja, Hofmann, Marco H, Liu, Kang, Kashyap, Abhishek

“…KRAS inhibitors have demonstrated exciting pre-clinical and clinical responses, although resistance occurs rapidly. Here, we investigate the effects of…”
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