Search Results - "Xia, Yinghao"
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Molecular Self-Assembly of Bioorthogonal Aptamer-Prodrug Conjugate Micelles for Hydrogen Peroxide and pH-Independent Cancer Chemodynamic Therapy
Published in Journal of the American Chemical Society (15-01-2020)“…Chemodynamic therapy (CDT) has demonstrated new possibilities for selective and logical cancer intervention by specific manipulation of dysregulated tumorous…”
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Dual-Parameter Recognition-Directed Design of the Activatable Fluorescence Probe for Precise Imaging of Cellular Senescence
Published in Analytical chemistry (Washington) (28-02-2023)“…Specific imaging of cellular senescence emerges as a promising strategy for early diagnosis and treatment of various age-related diseases. The currently…”
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Engineering Hierarchical Recognition‐Mediated Senolytics for Reliable Regulation of Cellular Senescence and Anti‐Atherosclerosis Therapy
Published in Angewandte Chemie International Edition (23-01-2023)“…Precise regulation of vascular senescence represents a far‐reaching strategy to combat age‐related diseases. However, the high heterogeneity of senescence,…”
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4
Spatially Selective Self-Amplified Imaging of Chemotherapy-Induced Cancer Senescence via Reversal of Impaired Ferritinophagy
Published in Analytical chemistry (Washington) (29-10-2024)“…Real-time monitoring of chemotherapy-induced senescence (CIS) in cancer remains a challenging task that would lead to new insights into the adaptive mechanisms…”
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Aptamer Conjugate-Based Ratiometric Fluorescent Probe for Precise Imaging of Therapy-Induced Cancer Senescence
Published in Analytical chemistry (Washington) (09-01-2024)“…Therapy-induced cellular senescence has been increasingly recognized as a key mechanism to promote various aspects of carcinogenesis in a nonautonomous manner…”
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A denoising method of ECG signal based on variational autoencoder and masked convolution
Published in Journal of electrocardiology (01-09-2023)“…Wearable electrocardiogram (ECG) equipment can realize continuous monitoring of cardiovascular diseases, but these devices are more susceptible to interference…”
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Spatially Confined Intervention of Cellular Senescence by a Lysosomal Metabolism Targeting Molecular Prodrug for Broad‐Spectrum Senotherapy
Published in Angewandte Chemie International Edition (14-03-2022)“…Specific intervention of senescent cells (SnCs) is emerging as a powerful means to counteract aging and age‐related diseases. Canonical methods are generally…”
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Recent Advances in Strategies for Imaging Detection and Intervention of Cellular Senescence
Published in Chembiochem : a European journal of chemical biology (03-01-2023)“…Cellular senescence is a stable cell cycle arrest state that can be triggered by a wide range of intrinsic or extrinsic stresses. Increased burden of senescent…”
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Modulation of ion-conducting groups in aqueous terpolymer binders to boost the electrochemical performance of silicon-based anodes
Published in Journal of power sources (15-09-2024)“…Silicon anodes hold great promise for the next-generation energy dense lithium-ion batteries (LIBs) due to their high specific capacity, yet the capacity of…”
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10
Beyond Blocking: Engineering RNAi-Mediated Targeted Immune Checkpoint Nanoblocker Enables T‑Cell-Independent Cancer Treatment
Published in ACS nano (22-12-2020)“…The emergence of immune checkpoint blockade to activate host T cells to attack tumor cells has revolutionized the cancer treatment landscape over the past…”
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Engineering AND-Gate Aptamer-Signal Base Conjugates for Targeted Magnetic Resonance Molecular Imaging of Metastatic Cancer
Published in ACS applied materials & interfaces (20-04-2022)“…In vivo noninvasive molecular imaging requires precise recognition and in situ, real-time imaging of specific cellular and molecular signatures at the site of…”
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12
Artificial Nucleobase-Directed Programmable Synthesis and Assembly of Amphiphilic Nucleic Acids as an All-in-One Platform for Cation-Free siRNA Delivery
Published in ACS applied materials & interfaces (05-10-2022)“…Efficient transport of nucleic acid therapeutics into targeted cells is the key step of genetic modulation in disease treatment. Nowadays, delivery systems…”
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13
Synthesis of Propylene Carbonate from Urea and 1,2-Propylene Glycol in a Monolithic Stirrer Reactor
Published in Industrial & engineering chemistry research (23-01-2013)“…A monolithic stirrer reactor, in which the cordierite monolith-supported metal oxide and mixed-metal oxide catalysts are used as stirrer blades, is applied for…”
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14
Engineering Hierarchical Recognition‐Mediated Senolytics for Reliable Regulation of Cellular Senescence and Anti‐Atherosclerosis Therapy
Published in Angewandte Chemie (23-01-2023)“…Precise regulation of vascular senescence represents a far‐reaching strategy to combat age‐related diseases. However, the high heterogeneity of senescence,…”
Get full text
Journal Article -
15
Spatially Confined Intervention of Cellular Senescence by a Lysosomal Metabolism Targeting Molecular Prodrug for Broad‐Spectrum Senotherapy
Published in Angewandte Chemie (14-03-2022)“…Specific intervention of senescent cells (SnCs) is emerging as a powerful means to counteract aging and age‐related diseases. Canonical methods are generally…”
Get full text
Journal Article