Search Results - "Xia, Shilin"
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The deubiquitinase USP10 regulates KLF4 stability and suppresses lung tumorigenesis
Published in Cell death and differentiation (01-06-2020)“…Krüppel-like factor 4 (KLF4), a key transcription factor, acts as a multifunctional player involved in the progression of numerous aggressive cancers. The…”
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2
The novel immune-related genes predict the prognosis of patients with hepatocellular carcinoma
Published in Scientific reports (21-05-2021)“…Hepatocellular carcinoma (HCC) is one of the main causes of cancer deaths globally. Immunotherapy is becoming increasingly important in the cure of advanced…”
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3
Identification of hub genes associated with COVID-19 and idiopathic pulmonary fibrosis by integrated bioinformatics analysis
Published in PloS one (19-01-2022)“…The coronavirus disease 2019 (COVID-19), emerged in late 2019, was caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The risk factors for…”
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4
Comprehensive characterization of extracellular matrix-related genes in PAAD identified a novel prognostic panel related to clinical outcomes and immune microenvironment: A silico analysis with in vivo and vitro validation
Published in Frontiers in immunology (13-10-2022)“…The extracellular matrix (ECM) is a vital component of the tumor microenvironment, which interplays with stromal and tumor cells to stimulate the capacity of…”
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5
Prognostic and immune-related value of STK17B in skin cutaneous melanoma
Published in PloS one (16-02-2022)“…Skin cutaneous melanoma (SKCM) is a common cancer of which mortality is increasing continuously. Our study conducted a series of analyses on the clinical…”
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6
Attribution of Responsibility for Pick Up Artist Issues in China: The Impacts of Journalist Gender, Geographical Location, and Publication Range
Published in The Journal of communication inquiry (01-04-2022)“…Pick-up artists (PUAs) apply strategies from evolutionary psychology to exploit women emotionally, sexually, and financially. In China, PUA issues have been…”
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INTS8 is a therapeutic target for intrahepatic cholangiocarcinoma via the integration of bioinformatics analysis and experimental validation
Published in Scientific reports (08-12-2021)“…Intrahepatic cholangiocarcinoma (CHOL) remains a rare malignancy, ranking as the leading lethal primary liver cancer worldwide. However, the biological…”
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8
Emodin Alleviates Sodium Taurocholate-Induced Pancreatic Acinar Cell Injury via MicroRNA-30a-5p-Mediated Inhibition of High-Temperature Requirement A/Transforming Growth Factor Beta 1 Inflammatory Signaling
Published in Frontiers in immunology (06-11-2017)“…Pancreatitis is an inflammatory disease that is responsible for substantial morbidity and mortality, and it can induce pancreatic necrosis that starts within…”
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CARD11 is a prognostic biomarker and correlated with immune infiltrates in uveal melanoma
Published in PloS one (09-08-2021)“…Uveal melanoma (UVM), the most common primary intraocular malignancy, has a high mortality because of a high propensity to metastasize. Our study analyzed…”
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10
T Lymphocytes: A Promising Immunotherapeutic Target for Pancreatitis and Pancreatic Cancer?
Published in Frontiers in oncology (24-03-2020)“…Pancreatic disorders cause a broad spectrum of clinical diseases, mainly including acute and chronic pancreatitis and pancreatic cancer, and are associated…”
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11
Targeting MicroRNA Function in Acute Pancreatitis
Published in Frontiers in physiology (21-09-2017)“…Acute pancreatitis (AP) is a common gastrointestinal disorder that featured by acute inflammatory responses leading to systemic inflammatory response syndrome…”
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12
WGCNA identification of TLR7 as a novel diagnostic biomarker, progression and prognostic indicator, and immunotherapeutic target for stomach adenocarcinoma
Published in Cancer medicine (Malden, MA) (01-06-2021)“…Stomach adenocarcinoma (STAD) is a malignant tumor with high histological heterogeneity. However, the potential mechanism of STAD tumorigenesis remains to be…”
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13
Identification and characterization of interferon-γ signaling-based personalized heterogeneity and therapeutic strategies in patients with pancreatic cancer
Published in Frontiers in oncology (24-10-2023)“…Background Interferon-γ (IFN-γ) is a key cytokine with diverse biological functions, including antiviral defense, antitumor activity, immune regulation, and…”
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14
Chinese Herbal Medicines Attenuate Acute Pancreatitis: Pharmacological Activities and Mechanisms
Published in Frontiers in pharmacology (25-04-2017)“…Acute pancreatitis (AP) is a commonly occurring gastrointestinal disorder. An increase in the annual incidence of AP has been observed, and it causes acute…”
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15
Improving the communication skills of medical students ——A survey of simulated patient-based learning in Chinese medical universities
Published in BMC medical education (13-07-2022)“…Abstract Background It is useful to advance simulated patient (SP) participation in teaching to improve the communication skills of medical students, so this…”
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16
The potential drug for treatment in pancreatic adenocarcinoma: a bioinformatical study based on distinct drug databases
Published in Chinese medicine (18-03-2020)“…The prediction of drug-target interaction from chemical and biological data can advance our search for potential drug, contributing to a therapeutic strategy…”
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17
The nine ADAMs family members serve as potential biomarkers for immune infiltration in pancreatic adenocarcinoma
Published in PeerJ (San Francisco, CA) (30-09-2020)“…The functional significance of ADAMs family members in the immune infiltration of pancreatic adenocarcinoma (PAAD) awaits elucidation. ADAMs family members…”
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Yin-Chen-Hao Tang Attenuates Severe Acute Pancreatitis in Rat: An Experimental Verification of In silico Network Target Prediction
Published in Frontiers in pharmacology (13-10-2016)“…Yin-Chen-Hao Tang (YCHT) is a classical Chinese medicine compound that has a long history of clinical use in China for the treatment of inflammatory diseases…”
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Bioinformatic evidences and analysis of putative biomarkers in pancreatic ductal adenocarcinoma
Published in Heliyon (01-08-2019)“…Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal human cancers. Aberrant expression of genes plays important role in the procession of PDAC…”
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Corrigendum: Yin-Chen-Hao Tang Attenuates Severe Acute Pancreatitis in Rat: An Experimental Verification of In silico Network Target Prediction
Published in Frontiers in pharmacology (17-10-2018)“…[This corrects the article DOI: 10.3389/fphar.2016.00378.]…”
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