Search Results - "Xia, Kaishun"

Strategies and prospects of effective neural circuits reconstruction after spinal cord injury by Yang, Biao, Zhang, Feng, Cheng, Feng, Ying, Liwei, Wang, Chenggui, Shi, Kesi, Wang, Jingkai, Xia, Kaishun, Gong, Zhe, Huang, Xianpeng, Yu, Cao, Li, Fangcai, Liang, Chengzhen, Chen, Qixin

“…Due to the disconnection of surviving neural elements after spinal cord injury (SCI), such patients had to suffer irreversible loss of motor or sensory…”
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Anti-CD166/4-1BB chimeric antigen receptor T cell therapy for the treatment of osteosarcoma by Wang, Yitian, Yu, Wei, Zhu, Jian, Wang, Junjie, Xia, Kaishun, Liang, Chengzhen, Tao, Huimin

“…Chimeric antigen receptor (CAR)-engineered T cells have displayed outstanding performance in the treatment of patients with hematological malignancies…”
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A bioactive injectable self-healing anti-inflammatory hydrogel with ultralong extracellular vesicles release synergistically enhances motor functional recovery of spinal cord injury by Wang, Chenggui, Wang, Min, Xia, Kaishun, Wang, Jingkai, Cheng, Feng, Shi, Kesi, Ying, Liwei, Yu, Chao, Xu, Haibin, Xiao, Shining, Liang, Chengzhen, Li, Fangcai, Lei, Bo, Chen, Qixin

“…The repair and motor functional recovery after spinal cord injury (SCI) remains a worldwide challenge. The inflammatory microenvironment is one of main…”
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lncRNAs: function and mechanism in cartilage development, degeneration, and regeneration by Zhu, Jian, Yu, Wei, Wang, Yitian, Xia, Kaishun, Huang, Yuluan, Xu, Ankai, Chen, Qixin, Liu, Bing, Tao, Huimin, Li, Fangcai, Liang, Chengzhen

“…With the increasing incidence of cartilage-related diseases such as osteoarthritis (OA) and intervertebral disc degeneration (IDD), heavier financial and…”
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Stem Cell Transplantation: A Promising Therapy for Spinal Cord Injury by Gong, Zhe, Xia, Kaishun, Xu, Ankai, Yu, Chao, Wang, Chenggui, Zhu, Jian, Huang, Xianpeng, Chen, QiXin, Li, Fangcai, Liang, Chengzhen

“…Spinal Cord Injury (SCI) causes irreversible functional loss of the affected population. The incidence of SCI keeps increasing, resulting in huge burden on the…”
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A conductive supramolecular hydrogel creates ideal endogenous niches to promote spinal cord injury repair by Yang, Biao, Liang, Chengzhen, Chen, Di, Cheng, Feng, Zhang, Yuang, Wang, Shaoke, Shu, Jiawei, Huang, Xianpeng, Wang, Jingkai, Xia, Kaishun, Ying, Liwei, Shi, Kesi, Wang, Chenggui, Wang, Xuhua, Li, Fangcai, Zhao, Qian, Chen, Qixin

“…The current effective method for treatment of spinal cord injury (SCI) is to reconstruct the biological microenvironment by filling the injured cavity area and…”
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Metabolic reprogramming: a new option for the treatment of spinal cord injury by Chen, Jiangjie, Chen, Jinyang, Yu, Chao, Xia, Kaishun, Yang, Biao, Wang, Ronghao, Li, Yi, Shi, Kesi, Zhang, Yuang, Xu, Haibin, Zhang, Xuesong, Wang, Jingkai, Chen, Qixin, Liang, Chengzhen

“…Spinal cord injuries impose a notably economic burden on society, mainly because of the severe after-effects they cause. Despite the ongoing development of…”
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Micro Fragmented Adipose Tissue Promotes the Matrix Synthesis Function of Nucleus Pulposus Cells and Regenerates Degenerated Intervertebral Disc in a Pig Model by Zhou, Xiaopeng, Zhang, Feng, Wang, Dawei, Wang, Jingkai, Wang, Chenggui, Xia, Kaishun, Ying, Liwei, Huang, Xianpeng, Tao, Yiqing, Chen, Shouyong, Xue, Deting, Hua, Jianming, Liang, Chengzhen, Chen, Qixin, Li, Fangcai

“…Intervertebral disc (IVD) degeneration and consequent lower back pain is a common disease. Micro fragmented adipose tissue (MFAT) is promising for a wide range…”
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Estrogen/ER in anti-tumor immunity regulation to tumor cell and tumor microenvironment by Wang, Tiecheng, Jin, Jiakang, Qian, Chao, Lou, Jianan, Lin, Jinti, Xu, Ankai, Xia, Kaishun, Jin, Libin, Liu, Bing, Tao, Huimin, Yang, Zhengming, Yu, Wei

“…Abstract As the essential sexual hormone, estrogen and its receptor has been proved to participate in the regulation of autoimmunity diseases and anti-tumor…”
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Injectable kartogenin and apocynin loaded micelle enhances the alleviation of intervertebral disc degeneration by adipose-derived stem cell by Yu, Chao, Li, Dongdong, Wang, Chenggui, Xia, Kaishun, Wang, Jingkai, Zhou, Xiaopeng, Ying, Liwei, Shu, Jiawei, Huang, Xianpeng, Xu, Haibin, Han, Bin, Chen, Qixin, Li, Fangcai, Tang, Jianbin, Liang, Chengzhen, Slater, Nigel

“…Cell transplantation has been proved the promising therapeutic effects on intervertebral disc degeneration (IVDD). However, the increased levels of reactive…”
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Intradiscal Injection of Induced Pluripotent Stem Cell-Derived Nucleus Pulposus-Like Cell-Seeded Polymeric Microspheres Promotes Rat Disc Regeneration by Yu, Wei, Gao, Jian-Qing, Chen, Qixin, Li, Fangcai, Liang, Chengzhen, Huang, Xianpeng, Wang, Jingkai, Zhou, Xiaopeng, Yu, Chao, Gong, Zhe, Hua, Jianming, Zhu, Jian, Xia, Kaishun, Li, Liming

“…Background. Cell replacement therapy is an attractive alternative for treating degenerated intervertebral discs (IVDs), which are related to the reduction of…”
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Endocytosis‐Inspired Zwitterionic Gel Tape for High‐Efficient and Sustainable Underoil Adhesion by Tang, Yueman, Si, Mengjie, Wang, Yan‐jie, Zhou, Jiahui, Deng, Yuming, Xia, Kaishun, Jiang, Zhen, Zhang, Dong, Zheng, Si Yu, Yang, Jintao

“…Marine oil exploration is important yet greatly increases the risk of oil leakage, which will result in severe environment pollution and economic losses. It is…”
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Differentiation of Pluripotent Stem Cells into Nucleus Pulposus Progenitor Cells for Intervertebral Disc Regeneration by Xia, Kaishun, Gong, Zhe, Zhu, Jian, Yu, Wei, Wang, Yitian, Wang, Junjie, Xu, Ankai, Zhou, Xiaopeng, Tao, Huimin, Li, Fangcai, Liang, Chengzhen

“…Low back pain (LBP) is one of the world's most common musculoskeletal diseases and is frequently associated with intervertebral disc degeneration (IDD). While…”
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The Application of Neural Stem/Progenitor Cells for Regenerative Therapy of Spinal Cord Injury by Yu, Chao, Xia, Kaishun, Gong, Zhe, Ying, Liwei, Shu, Jiawei, Zhang, Feng, Chen, Qixin, Li, Fangcai, Liang, Chengzhen

“…Spinal cord injury (SCI) is a devastating event, and there are still no effective therapies currently available. Neural stem cells (NSCs) have gained…”
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Metabolic Glycoengineering: A Promising Strategy to Remodel Microenvironments for Regenerative Therapy by Li, Yi, Zhang, Yuang, Tao, Yiqin, Huang, Xianpeng, Yu, Chao, Xu, Haibin, Chen, Jiangjie, Xia, Kaishun, Shi, Kesi, Zhang, Yongxiang, Wang, Jingkai, Shu, Jiawei, Cheng, Feng, Wang, Shaoke, Liang, Chengzhen, Li, Fangcai, Zhou, Xiaopeng, Chen, Qixin

“…Cell-based regenerative therapy utilizes the differentiation potential of stem cells to rejuvenate tissues. But the dynamic fate of stem cells is calling for…”
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Allogenic γδ T cell and tumor cell fused vaccine for enhanced immunotherapeutic efficacy of osteosarcoma by Wang, Yitian, Zhu, Jian, Yu, Wei, Wang, Junjie, Xia, Kaishun, Liang, Chengzhen, Tao, Huimin

“…Human γδ T cells have displayed their potential in cancer immunity through efficient tumor killing activities. Besides, they are also known for their capacity…”
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Thermosensitive hydrogel-based GPR124 delivery strategy for rebuilding blood-spinal cord barrier by Shu, Jiawei, Wang, Chenggui, Tao, Yiqing, Wang, Shaoke, Cheng, Feng, Zhang, Yuang, Shi, Kesi, Xia, Kaishun, Wang, Ronghao, Wang, Jingkai, Yu, Chao, Chen, Jiangjie, Huang, Xianpeng, Xu, Haibin, Zhou, Xiaopeng, Wu, Haobo, Liang, Chengzhen, Chen, Qixin, Yan, Shigui, Li, Fangcai

“…Spinal cord injury (SCI) causes blood-spinal cord barrier (BSCB) disruption, leading to secondary damage, such as hemorrhagic infiltration, inflammatory…”
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Silencing circATXN1 in Aging Nucleus Pulposus Cell Alleviates Intervertebral Disc Degeneration via Correcting Progerin Mislocalization by Yu, Chao, Zhao, Jing, Cheng, Feng, Chen, Jiangjie, Chen, Jinyang, Xu, Haibin, Shi, Kesi, Xia, Kaishun, Ding, Siwen, Wang, Kanbin, Wang, Ronghao, Chen, Yazhou, Li, Yi, Li, Hao, Chen, Qixin, Yu, Xiaohua, Shao, Fangwei, Liang, Chengzhen, Li, Fangcai

“…Circular RNAs (circRNAs) play a critical regulatory role in degenerative diseases; however, their functions and therapeutic applications in intervertebral disc…”
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Autophagy inhibitor enhance ZnPc/BSA nanoparticle induced photodynamic therapy by suppressing PD-L1 expression in osteosarcoma immunotherapy by Yu, Wei, Wang, Yitian, Zhu, Jian, Jin, Libin, Liu, Bing, Xia, Kaishun, Wang, Junjie, Gao, Jianqing, Liang, Chengzhen, Tao, Huimin

“…Elevated expression of programmed death ligand-1 (PD-L1) on the surface of tumor cells can exhaust cytotoxic T lymphocyte cells and lead to the failure of…”
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A facile strategy to fabricate stretchable, low hysteresis and adhesive zwitterionic elastomers by concentration-induced polymerization for wound healing by Luo, Jinhui, Shen, Zhenxiang, Jian, Wei, Wang, Shuaibing, Li, Yizhen, Xia, Kaishun, Zheng, Si Yu, Yang, Jintao

“…We have developed a multi-functional zwitterionic elastomer (TASM) based on a facile method for wound healing, which shows a combination of robust adhesion,…”
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