Search Results - "Xi, Guangmin"

Downregulation of GSDMD attenuates tumor proliferation via the intrinsic mitochondrial apoptotic pathway and inhibition of EGFR/Akt signaling and predicts a good prognosis in non‑small cell lung cancer by Gao, Jianwei, Qiu, Xiangyu, Xi, Guangmin, Liu, Hongbing, Zhang, Fang, Lv, Tangfeng, Song, Yong

“…Gasdermin D (GSDMD) is a newly discovered pyroptosis executive protein, which can be cleaved by inflammatory caspases and is essential for secretion of IL‑1β,…”
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Knockdown of NEK7 alleviates anterior cruciate ligament transection osteoarthritis (ACLT)-induced knee osteoarthritis in mice via inhibiting NLRP3 activation by Sun, Wei, Yue, Maoxing, Xi, Guangmin, Wang, Kai, Sai, Jiaming

“…Osteoarthritis is thought to be a NLRP3-related disease. NEK7 is an essential mediator for NLRP3 inflammasome activation. This study aimed to demonstrate…”
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Autophagy inhibition promotes paclitaxel-induced apoptosis in cancer cells by Xi, Guangmin, Hu, Xiaoyan, Wu, Baolin, Jiang, Hanming, Young, Charles Y.F, Pang, Yingxin, Yuan, Huiqing

“…Abstract Paclitaxel has been demonstrated to be an effective mitotic inhibitor and apoptosis inducer to treat aggressive malignancies. In this paper, we have…”
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Embelin Enhances the Sensitivity of Renal Cancer Cells to Axitinib by Inhibiting HIF Signaling Pathway by Fang, Qiong, Li, Zhiying, Xue, Ye, Zong, Xin, Ma, Wenshuang, Xi, Guangmin, Zhang, Xiao Feng, Li, Zuowei

“…Renal cell carcinoma (RCC) is a common malignant tumor of the urinary system with a high recurrence rate and easy metastasis. Current clinical drugs for renal…”
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GSDMD is required for effector CD8+ T cell responses to lung cancer cells by Xi, Guangmin, Gao, Jianwei, Wan, Bing, Zhan, Ping, Xu, Wujian, Lv, Tangfeng, Song, Yong

“…GSDMD is a recently discovered pyroptosis executioner in monocytes whose N-terminal domain can insert into the inner leaflet of cell membranes and form…”
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OASL knockdown inhibits the progression of stomach adenocarcinoma by regulating the mTORC1 signaling pathway by Zhao, Weizhu, Yang, Haiying, Liu, Luguang, Qu, Xianlin, Ding, Jishuang, Yu, Hang, Xu, Botao, Zhao, Siwei, Xi, Guangmin, Xing, Ligang, Chai, Jie

“…The present study investigated the effects of 2′‐5′ oligoadenylate synthetase‐like (OASL) on the biological functions of stomach adenocarcinoma (STAD) cells…”
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The protective effect of dopamine on ventilator-induced lung injury via the inhibition of NLRP3 inflammasome by Yang, Xiaomei, Sun, Xiaotong, Chen, Hongli, Xi, Guangmin, Hou, Yonghao, Wu, Jianbo, Liu, Dejie, Wang, Huanliang, Hou, Yuedong, Yu, Jingui

“…Dopamine (DA), a neurotransmitter, was previously shown to have anti-inflammatory effects. However, its role in ventilator-induced lung injury (VILI) has not…”
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Luteolin impacts deoxyribonucleic acid repair by modulating the mitogen-activated protein kinase pathway in colorectal cancer by Song, Yelin, Yu, Jie, Li, LingLing, Wang, Lei, Dong, Liangle, Xi, Guangmin, Lu, Yun Jing, Li, Zuowei

“…This study aimed to investigate the effects of luteolin on colorectal cancer (CRC) and explore its underlying mechanism. HCT-116 and HT-29 cells were treated…”
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Overexpression of geranylgeranyl diphosphate synthase contributes to tumour metastasis and correlates with poor prognosis of lung adenocarcinoma by Wang, Xiaoxia, Xu, Wujian, Zhan, Ping, Xu, Tianxiang, Jin, Jiajia, Miu, Yingying, Zhou, Zejun, Zhu, Qingqing, Wan, Bing, Xi, Guangmin, Ye, Liang, Liu, Yafang, Gao, Jianwei, Li, Huijuan, Lv, Tangfeng, Song, Yong

“…This study aimed to evaluate the biological role of geranylgeranyl diphosphate synthase (GGPPS) in the progression of lung adenocarcinoma. GGPPS expression was…”
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Targeting autophagy augments the activity of DHA-E3 to overcome p-gp mediated multi-drug resistance by Xi, Guangmin, Wang, Ming, Sun, Bing, Shaikh, Abdul Sami, Liu, Yongqing, Wang, Wei, Lou, Hongxiang, Yuan, Huiqing

“…Abstract Multidrug resistance (MDR) is a major obstacle for successful chemotherapy treatment. Searching for effective MDR modulators and combining them with…”
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