Search Results - "Xi, C."

The regulatory niche of intestinal stem cells by Sailaja, Badi Sri, He, Xi C., Li, Linheng

“…The niche constitutes a unique category of cells that support the microenvironment for the maintenance and self‐renewal of stem cells. Intestinal stem cells…”
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Impaired TFEB-Mediated Lysosome Biogenesis and Autophagy Promote Chronic Ethanol-Induced Liver Injury and Steatosis in Mice by Chao, Xiaojuan, Wang, Shaogui, Zhao, Katrina, Li, Yuan, Williams, Jessica A., Li, Tiangang, Chavan, Hemantkumar, Krishnamurthy, Partha, He, Xi C., Li, Linheng, Ballabio, Andrea, Ni, Hong-Min, Ding, Wen-Xing

“…Defects in lysosome function and autophagy contribute to the pathogenesis of alcoholic liver disease. We investigated the mechanisms by which alcohol…”
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Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells by Zhao, Meng, Perry, John M, Marshall, Heather, Venkatraman, Aparna, Qian, Pengxu, He, Xi C, Ahamed, Jasimuddin, Li, Linheng

“…Two papers in this issue, by Bruns et al . and Zhao et al ., show that megakaryocytes constitute a niche for hematopoietic stem cells in the mouse bone marrow…”
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Noncanonical Wnt Signaling Maintains Hematopoietic Stem Cells in the Niche by Sugimura, Ryohichi, He, Xi C., Venkatraman, Aparna, Arai, Fumio, Box, Andrew, Semerad, Craig, Haug, Jeffrey S., Peng, Lai, Zhong, Xiao-bo, Suda, Toshio, Li, Linheng

“…Wnt signaling is involved in self-renewal and maintenance of hematopoietic stem cells (HSCs); however, the particular role of noncanonical Wnt signaling in…”
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Current View: Intestinal Stem Cells and Signaling by Scoville, David H, Sato, Toshiro, He, Xi C, Li, Linheng

“…Studies using mice have yielded significant amounts of information regarding signaling pathways, such as Wnt, bone morphogenic protein, PtdIns(3,4,5) kinase,…”
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Three-component fermions with surface Fermi arcs in tungsten carbide by Ma, J.-Z., He, J.-B., Xu, Y.-F., Lv, B. Q., Chen, D., Zhu, W.-L., Zhang, S., Kong, L.-Y., Gao, X., Rong, L.-Y., Huang, Y.-B., Richard, P., Xi, C.-Y., Choi, E. S., Shao, Y., Wang, Y.-L., Gao, H.-J., Dai, X., Fang, C., Weng, H.-M., Chen, G.-F., Qian, T., Ding, H.

“…Topological Dirac and Weyl semimetals not only host quasiparticles analogous to the elementary fermionic particles in high-energy physics, but also have a…”
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The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism by Qian, Pengxu, He, Xi C., Paulson, Ariel, Li, Zhenrui, Tao, Fang, Perry, John M., Guo, Fengli, Zhao, Meng, Zhi, Lei, Venkatraman, Aparna, Haug, Jeffrey S., Parmely, Tari, Li, Hua, Dobrowsky, Rick T., Ding, Wen-Xing, Kono, Tomohiro, Ferguson-Smith, Anne C., Li, Linheng

“…The mammalian imprinted Dlk1-Gtl2 locus produces multiple non-coding RNAs (ncRNAs) from the maternally inherited allele, including the largest miRNA cluster in…”
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Stress-protecting harbors for hematopoietic stem cells by Yang, Zhe, Dong, Ruochen, Mao, Xinjian, He, Xi C., Li, Linheng

“…Hematopoietic stem cells (HSCs) rely on specialized microenvironments known as niches to maintain their self-renewal and multilineage potential to generate…”
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N-Cadherin-Expressing Bone and Marrow Stromal Progenitor Cells Maintain Reserve Hematopoietic Stem Cells by Zhao, Meng, Tao, Fang, Venkatraman, Aparna, Li, Zhenrui, Smith, Sarah E., Unruh, Jay, Chen, Shiyuan, Ward, Christina, Qian, Pengxu, Perry, John M., Marshall, Heather, Wang, Jinxi, He, Xi C., Li, Linheng

“…Regulation of hematopoietic stem cells (HSCs) by bone marrow (BM) niches has been extensively studied; however, whether and how HSC subpopulations are…”
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Atlas of the human intestine by He, Xi C, Li, Linheng

“…In this issue of JEM, Wang et al. (https://doi.org/10.1084/jem.20191130), using a single-cell RNA-seq approach, establish an atlas of human colon, rectum, and…”
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Hematopoietic stem cells: self-renewal and expansion by Li, Zhenrui, He, Xi C, Li, Linheng

“…Hematopoietic stem cells (HSCs) are a unique population of cells with the remarkable ability to replenish themselves through self-renewal and to give rise to…”
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Maternal imprinting at the H19–Igf2 locus maintains adult haematopoietic stem cell quiescence by Venkatraman, Aparna, He, Xi C., Thorvaldsen, Joanne L., Sugimura, Ryohichi, Perry, John M., Tao, Fang, Zhao, Meng, Christenson, Matthew K., Sanchez, Rebeca, Yu, Jaclyn Y., Peng, Lai, Haug, Jeffrey S., Paulson, Ariel, Li, Hua, Zhong, Xiao-bo, Clemens, Thomas L., Bartolomei, Marisa S., Li, Linheng

“…Maternal genomic imprinting is crucial for the maintenance of adult stem cells, which is accomplished by maintaining long-term haematopoietic stem cell…”
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Intestinal epithelial regeneration: active versus reserve stem cells and plasticity mechanisms by Karmakar, Soham, Deng, Lu, He, Xi C, Li, Linheng

“…The gastrointestinal system is arguably one of the most complicated developmental systems in a multicellular organism, as it carries out at least four major…”
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Detection of functional haematopoietic stem cell niche using real-time imaging by Feldman, Ricardo A, Li, Linheng, Xie, Yucai, Yin, Tong, Wiegraebe, Winfried, He, Xi C, Miller, Diana, Stark, Danny, Perko, Katherine, Alexander, Richard, Schwartz, Joel, Grindley, Justin C, Park, Jungeun, Haug, Jeff S, Wunderlich, Joshua P, Li, Hua, Zhang, Simon, Johnson, Teri

“…Haematopoietic stem cell (HSC) niches, although proposed decades ago, have only recently been identified as separate osteoblastic and vascular…”
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Isolation and Characterization of Intestinal Stem Cells Based on Surface Marker Combinations and Colony-Formation Assay by Wang, Fengchao, Scoville, David, He, Xi C, Mahe, Maxime M, Box, Andrew, Perry, John M, Smith, Nicholas R, Lei, Nan Ye, Davies, Paige S, Fuller, Megan K, Haug, Jeffrey S, McClain, Melainia, Gracz, Adam D, Ding, Sheng, Stelzner, Matthias, Dunn, James C.Y, Magness, Scott T, Wong, Melissa H, Martin, Martin G, Helmrath, Michael, Li, Linheng

“…Background & Aims Identification of intestinal stem cells (ISCs) has relied heavily on the use of transgenic reporters in mice, but this approach is limited by…”
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Overcoming Wnt–β-catenin dependent anticancer therapy resistance in leukaemia stem cells by Perry, John M., Tao, Fang, Roy, Anuradha, Lin, Tara, He, Xi C., Chen, Shiyuan, Lu, Xiuling, Nemechek, Jacqelyn, Ruan, Linhao, Yu, Xiazhen, Dukes, Debra, Moran, Andrea, Pace, Jennifer, Schroeder, Kealan, Zhao, Meng, Venkatraman, Aparna, Qian, Pengxu, Li, Zhenrui, Hembree, Mark, Paulson, Ariel, He, Zhiquan, Xu, Dong, Tran, Thanh-Huyen, Deshmukh, Prashant, Nguyen, Chi Thanh, Kasi, Rajeswari M., Ryan, Robin, Broward, Melinda, Ding, Sheng, Guest, Erin, August, Keith, Gamis, Alan S., Godwin, Andrew, Sittampalam, G. Sitta, Weir, Scott J., Li, Linheng

“…Leukaemia stem cells (LSCs) underlie cancer therapy resistance but targeting these cells remains difficult. The Wnt–β-catenin and PI3K–Akt pathways cooperate…”
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Td-MoTe2: A possible topological superconductor by Luo, X., Chen, F. C., Zhang, J. L., Pei, Q. L., Lin, G. T., Lu, W. J., Han, Y. Y., Xi, C. Y., Song, W. H., Sun, Y. P.

“…We measured the magnetoresistivity properties of Td-MoTe2 single crystal under the magnetic field up to 33 T. By analyzing the Shubnikov–de Haas oscillations…”
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Lack of VMP1 impairs hepatic lipoprotein secretion and promotes non-alcoholic steatohepatitis by Jiang, Xiaoxiao, Fulte, Sam, Deng, Fengyan, Chen, Shiyuan, Xie, Yan, Chao, Xiaojuan, He, Xi C., Zhang, Yuxia, Li, Tiangang, Li, Feng, McCoin, Colin, Morris, E. Matthew, Thyfault, John, Liu, Wanqing, Li, Linheng, Davidson, Nicholas O., Ding, Wen-Xing, Ni, Hong-Min

“…Vacuole membrane protein 1 (VMP1) is an endoplasmic reticulum (ER) transmembrane protein that regulates the formation of autophagosomes and lipid droplets…”
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Superconductivity enhancement in the S-doped Weyl semimetal candidate MoTe2 by Chen, F. C., Luo, X., Xiao, R. C., Lu, W. J., Zhang, B., Yang, H. X., Li, J. Q., Pei, Q. L., Shao, D. F., Zhang, R. R., Ling, L. S., Xi, C. Y., Song, W. H., Sun, Y. P.

“…Two-dimensional transition-metal dichalcogenide (TMDs) MoTe2 has attracted much attention due to its predicted Weyl semimetal state and a quantum spin Hall…”
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Cooperation between both Wnt/β-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion by Perry, John M., He, Xi C., Sugimura, Ryohichi, Grindley, Justin C., Haug, Jeffrey S., Ding, Sheng, Li, Linheng

“…Although self-renewal is the central property of stem cells, the underlying mechanism remains inadequately defined. Using a hematopoietic stem and progenitor…”
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