Search Results - "Xavier C. Ding"

Development and validation of serological markers for detecting recent Plasmodium vivax infection by Longley, Rhea J., White, Michael T., Takashima, Eizo, Brewster, Jessica, Morita, Masayuki, Harbers, Matthias, Obadia, Thomas, Robinson, Leanne J., Matsuura, Fumie, Liu, Zoe S. J., Li-Wai-Suen, Connie S. N., Tham, Wai-Hong, Healer, Julie, Huon, Christele, Chitnis, Chetan E., Nguitragool, Wang, Monteiro, Wuelton, Proietti, Carla, Doolan, Denise L., Siqueira, Andre M., Ding, Xavier C., Gonzalez, Iveth J., Kazura, James, Lacerda, Marcus, Sattabongkot, Jetsumon, Tsuboi, Takafumi, Mueller, Ivo

“…A major gap in the Plasmodium vivax elimination toolkit is the identification of individuals carrying clinically silent and undetectable liver-stage parasites,…”
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Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins by Ding, Xavier C, Großhans, Helge

“…MicroRNAs (miRNAs) repress target genes through a poorly defined antisense mechanism. Cell‐free and cell‐based assays have supported the idea that miRNAs…”
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Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection by Roger, Thierry, Lugrin, Jérôme, Le Roy, Didier, Goy, Geneviève, Mombelli, Matteo, Koessler, Thibaud, Ding, Xavier C., Chanson, Anne-Laure, Reymond, Marlies Knaup, Miconnet, Isabelle, Schrenzel, Jacques, François, Patrice, Calandra, Thierry

“…Regulated by histone acetyltransferases and deacetylases (HDACs), histone acetylation is a key epigenetic mechanism controlling chromatin structure, DNA…”
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Analytical sensitivity of current best-in-class malaria rapid diagnostic tests by Jimenez, Alfons, Rees-Channer, Roxanne R, Perera, Rushini, Gamboa, Dionicia, Chiodini, Peter L, González, Iveth J, Mayor, Alfredo, Ding, Xavier C

“…Rapid diagnostic tests (RDTs) are today the most widely used method for malaria diagnosis and are recommended, alongside microscopy, for the confirmation of…”
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Acceptance and perceived value of non-invasive malaria diagnostic tests in malaria-endemic countries by Owusu, Ewurama Dedea Ampadu, Campillo, Ana, Daily, Jennifer, Ding, Xavier C

“…Background The diagnosis of malaria, using microscopy or rapid diagnostic tests (RDTs), requires the collection of capillary blood. This procedure is…”
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P. falciparum in vitro killing rates allow to discriminate between different antimalarial mode-of-action by Sanz, Laura M, Crespo, Benigno, De-Cózar, Cristina, Ding, Xavier C, Llergo, Jose L, Burrows, Jeremy N, García-Bustos, Jose F, Gamo, Francisco-Javier

“…Chemotherapy is still the cornerstone for malaria control. Developing drugs against Plasmodium parasites and monitoring their efficacy requires methods to…”
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Diagnostic Performance of Conventional and Ultrasensitive Rapid Diagnostic Tests for Malaria in Febrile Outpatients in Tanzania by Hofmann, Natalie E, Antunes Moniz, Clara, Holzschuh, Aurel, Keitel, Kristina, Boillat-Blanco, Noémie, Kagoro, Frank, Samaka, Josephine, Mbarack, Zainab, Ding, Xavier C, González, Iveth J, Genton, Blaise, D’Acremont, Valérie, Felger, Ingrid

“…Abstract Background A novel ultrasensitive malaria rapid diagnostic test (us-RDT) has been developed for improved active Plasmodium falciparum infection…”
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Performance and utility of more highly sensitive malaria rapid diagnostic tests by Slater, Hannah C, Ding, Xavier C, Knudson, Sophia, Bridges, Daniel J, Moonga, Hawela, Saad, Neil J, De Smet, Martin, Bennett, Adam, Dittrich, Sabine, Slutsker, Laurence, Domingo, Gonzalo J

“…A new more highly sensitive rapid diagnostic test (HS-RDT) for Plasmodium falciparum malaria (Alere™/Abbott Malaria Ag P.f RDT [05FK140], now called NxTek™…”
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Development and clinical performance of high throughput loop-mediated isothermal amplification for detection of malaria by Perera, Rushini S, Ding, Xavier C, Tully, Frank, Oliver, James, Bright, Nigel, Bell, David, Chiodini, Peter L, Gonzalez, Iveth J, Polley, Spencer D

“…Accurate and efficient detection of sub-microscopic malaria infections is crucial for enabling rapid treatment and interruption of transmission. Commercially…”
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Implementing radical cure diagnostics for malaria: user perspectives on G6PD testing in Bangladesh by Engel, Nora, Ghergu, Cristian, Matin, Mohammad Abdul, Kibria, Mohammad Golam, Thriemer, Kamala, Price, Ric N, Ding, Xavier C, Howes, Rosalind E, Ley, Benedikt, Incardona, Sandra, Alam, Mohammad Shafiul

“…The radical cure of Plasmodium vivax requires treatment with an 8-aminoquinoline drug, such as primaquine and tafenoquine, to eradicate liver hypnozoite…”
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Loop-mediated isothermal DNA amplification for asymptomatic malaria detection in challenging field settings: Technical performance and pilot implementation in the Peruvian Amazon by Serra-Casas, Elisa, Manrique, Paulo, Ding, Xavier C, Carrasco-Escobar, Gabriel, Alava, Freddy, Gave, Anthony, Rodriguez, Hugo, Contreras-Mancilla, Juan, Rosas-Aguirre, Angel, Speybroeck, Niko, González, Iveth J, Rosanas-Urgell, Anna, Gamboa, Dionicia

“…Loop-mediated isothermal DNA amplification (LAMP) methodology offers an opportunity for point-of-care (POC) molecular detection of asymptomatic malaria…”
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Quantification of malaria antigens PfHRP2 and pLDH by quantitative suspension array technology in whole blood, dried blood spot and plasma by Martiáñez-Vendrell, Xavier, Jiménez, Alfons, Vásquez, Ana, Campillo, Ana, Incardona, Sandra, González, Raquel, Gamboa, Dionicia, Torres, Katherine, Oyibo, Wellington, Faye, Babacar, Macete, Eusebio, Menéndez, Clara, Ding, Xavier C, Mayor, Alfredo

“…Malaria diagnostics by rapid diagnostic test (RDT) relies primarily on the qualitative detection of Plasmodium falciparum histidine-rich protein 2 (PfHRP2) and…”
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Comparison of two malaria multiplex immunoassays that enable quantification of malaria antigens by Jang, Ihn Kyung, Jiménez, Alfons, Rashid, Andrew, Barney, Rebecca, Golden, Allison, Ding, Xavier C, Domingo, Gonzalo J, Mayor, Alfredo

“…Immunoassay platforms that simultaneously detect malaria antigens including histidine-rich protein 2 (HRP2)/HRP3 and Plasmodium lactate dehydrogenase (pLDH),…”
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Malaria in pregnancy (MiP) studies assessing the clinical performance of highly sensitive rapid diagnostic tests (HS-RDT) for Plasmodium falciparum detection by Ding, Xavier C, Incardona, Sandra, Serra-Casas, Elisa, Charnaud, Sarah C, Slater, Hannah C, Domingo, Gonzalo J, Adams, Emily R, Ter Kuile, Feiko O, Samuels, Aaron M, Kariuki, Simon, Dittrich, Sabine

“…Rapid diagnostic tests (RDTs) are effective tools to diagnose and inform the treatment of malaria in adults and children. The recent development of a highly…”
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Molecular assays for antimalarial drug resistance surveillance: A target product profile by Nsanzabana, Christian, Ariey, Frederic, Beck, Hans-Peter, Ding, Xavier C, Kamau, Edwin, Krishna, Sanjeev, Legrand, Eric, Lucchi, Naomi, Miotto, Olivo, Nag, Sidsel, Noedl, Harald, Roper, Cally, Rosenthal, Philip J, Schallig, Henk D F H, Taylor, Steve M, Volkman, Sarah K, Gonzalez, Iveth J

“…Antimalarial drug resistance is a major constraint for malaria control and elimination efforts. Artemisinin-based combination therapy is now the mainstay for…”
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Patient-level performance evaluation of a smartphone-based malaria diagnostic application by Yu, Hang, Mohammed, Fayad O, Abdel Hamid, Muzamil, Yang, Feng, Kassim, Yasmin M, Mohamed, Abdelrahim O, Maude, Richard J, Ding, Xavier C, Owusu, Ewurama D A, Yerlikaya, Seda, Dittrich, Sabine, Jaeger, Stefan

“…Microscopic examination is commonly used for malaria diagnosis in the field. However, the lack of well-trained microscopists in malaria-endemic areas impacted…”
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Defining the next generation of Plasmodium vivax diagnostic tests for control and elimination: Target product profiles by Ding, Xavier C, Ade, Maria Paz, Baird, J Kevin, Cheng, Qin, Cunningham, Jane, Dhorda, Mehul, Drakeley, Chris, Felger, Ingrid, Gamboa, Dionicia, Harbers, Matthias, Herrera, Socrates, Lucchi, Naomi, Mayor, Alfredo, Mueller, Ivo, Sattabongkot, Jetsumon, Ratsimbason, Arsène, Richards, Jack, Tanner, Marcel, González, Iveth J

“…The global prevalence of malaria has decreased over the past fifteen years, but similar gains have not been realized against Plasmodium vivax because this…”
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Regulating the regulators: mechanisms controlling the maturation of microRNAs by Ding, Xavier C, Weiler, Jan, Großhans, Helge

“…MicroRNAs (miRNAs) are small noncoding RNAs that control diverse cellular and developmental events through repression of large sets of target mRNAs. Regulated…”
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Prevalence and clinical impact of malaria infections detected with a highly sensitive HRP2 rapid diagnostic test in Beninese pregnant women by Briand, Valérie, Cottrell, Gilles, Tuike Ndam, Nicaise, Martiáñez-Vendrell, Xavier, Vianou, Bertin, Mama, Atika, Kouwaye, Bienvenue, Houzé, Sandrine, Bailly, Justine, Gbaguidi, Erasme, Sossou, Darius, Massougbodji, Achille, Accrombessi, Manfred, Mayor, Alfredo, Ding, Xavier C, Fievet, Nadine

“…While sub-microscopic malarial infections are frequent and potentially deleterious during pregnancy, routine molecular detection is still not feasible. This…”
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Field Evaluation of a High Throughput Loop Mediated Isothermal Amplification Test for the Detection of Asymptomatic Plasmodium Infections in Zanzibar by Aydin-Schmidt, Berit, Morris, Ulrika, Ding, Xavier C, Jovel, Irina, Msellem, Mwinyi I, Bergman, Daniel, Islam, Atiqul, Ali, Abdullah S, Polley, Spencer, Gonzalez, Iveth J, Mårtensson, Andreas, Björkman, Anders

“…New field applicable diagnostic tools are needed for highly sensitive detection of residual malaria infections in pre-elimination settings. Field performance…”
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