Search Results - "Xavier, Léder Leal"
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SARS-CoV-2 mutations in Brazil: from genomics to putative clinical conditions
Published in Scientific reports (07-06-2021)“…Due to the high rate of transmissibility, Brazil became the new COVID-19 outbreak epicenter and, since then, is being monitored to understand how SARS-CoV-2…”
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2
Physical exercise reverses spatial memory deficit and induces hippocampal astrocyte plasticity in diabetic rats
Published in Brain research (15-01-2017)“…Abstract Physical exercise can induce brain plasticity and reduce the cognitive decline observed in type 1 diabetes mellitus (T1DM). We investigated the…”
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Physical training improves non-spatial memory, locomotor skills and the blood brain barrier in diabetic rats
Published in Brain research (27-08-2015)“…Abstract Type 1 diabetes mellitus (T1DM) progressively affects cognitive domains, increases blood–brain barrier (BBB) permeability and promotes neurovascular…”
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4
Can anxiety-like behavior and spatial memory predict the extremes of skilled walking performance in mice? An exploratory, preliminary study
Published in Frontiers in behavioral neuroscience (28-02-2023)“…Skilled walking is influenced by memory, stress, and anxiety. While this is evident in cases of neurological disorders, memory, and anxiety traits may predict…”
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5
New therapy of skin repair combining adipose-derived mesenchymal stem cells with sodium carboxymethylcellulose scaffold in a pre-clinical rat model
Published in PloS one (02-05-2014)“…Lesions with great loss of skin and extensive burns are usually treated with heterologous skin grafts, which may lead rejection. Cell therapy with mesenchymal…”
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6
Does Angiotensin II Peak in Response to SARS-CoV-2?
Published in Frontiers in immunology (14-01-2021)“…Human infection by the SARS-CoV-2 is causing the current COVID-19 pandemic. With the growing numbers of cases and deaths, there is an urgent need to explore…”
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7
Behavior outcome after ischemic and hemorrhagic stroke, with similar brain damage, in rats
Published in Behavioural brain research (01-05-2013)“…► ET-1 and collagenase could produce comparable ischemic and hemorrhagic injuries. ► Ischemic and hemorrhagic rats showed similar spontaneous locomotor…”
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8
Conventional Mirror Therapy versus Immersive Virtual Reality Mirror Therapy: The Perceived Usability after Stroke
Published in Stroke research and treatment (25-05-2023)“…Background. Stroke is a widespread and complex health issue, with many survivors requiring long-term rehabilitation due to upper-limb impairment. This study is…”
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Hemispheric Brain Injury and Behavioral Deficits Induced by Severe Neonatal Hypoxia-Ischemia in Rats Are Not Attenuated by Intravenous Administration of Human Umbilical Cord Blood Cells
Published in Pediatric research (01-06-2009)“…Neonatal hypoxia-ischemia (HI) is an important cause of mortality and morbidity in infants. Human umbilical cord blood (HUCB) is a potential source of cellular…”
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10
Rat Adipose-Derived Stromal Cells (ADSCs) Increases the Glioblastoma Growth and Decreases the Animal Survival
Published in Stem cell reviews and reports (01-04-2022)“…Many studies have shown that mesenchymal stromal cells (MSCs) and their secreted factors may modulate the biology of tumor cells. However, how these…”
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11
Effects of tannery wastewater exposure on adult Drosophila melanogaster
Published in Environmental science and pollution research international (01-12-2017)“…Our aim was to evaluate the effects of exposure to tannery wastewater on mortality and/or antioxidant enzyme system in adult wild-type Canton-S Drosophila…”
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12
Octyl gallate induces hepatic steatosis in HepG2 cells through the regulation of SREBP-1c and PPAR-gamma gene expression
Published in EXCLI journal (01-01-2020)“…Octyl gallate (OG) is an antioxidant commonly used in food, although there is no definition of its acceptable daily intake. There are reports and showing that…”
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13
The Foot Fault Scoring System to Assess Skilled Walking in Rodents: A Reliability Study
Published in Frontiers in behavioral neuroscience (29-04-2022)“…The foot fault scoring system of the ladder rung walking test (LRWT) is used to assess skilled walking in rodents. However, the reliability of the LRWT foot…”
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Morphological and mechanical changes induced by quercetin in human T24 bladder cancer cells
Published in Micron (Oxford, England : 1993) (01-12-2021)“…•Quercetin lead to morphological alterations in T24 cells in a dose-dependent manner.•Quercetin lead to alterations to nuclear morphology.•Apoptosis is the…”
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15
Physical exercise increases GFAP expression and induces morphological changes in hippocampal astrocytes
Published in Brain Structure and Function (2014)“…Physical exercise has an important influence on brain plasticity, which affects the neuron–glia interaction. Astrocytes are susceptible to plasticity, and…”
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16
Age-related tolerance to paraquat-induced parkinsonism in Drosophila melanogaster
Published in Toxicology letters (15-05-2022)“…Paraquat (PQ) is a widely used herbicide that can cross the dopaminergic neuronal membrane, accumulate in mitochondria and damage complex I of the electron…”
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Experimental Post-traumatic Stress Disorder Decreases Astrocyte Density and Changes Astrocytic Polarity in the CA1 Hippocampus of Male Rats
Published in Neurochemical research (01-04-2016)“…Post-traumatic stress disorder (PTSD) is a psychiatric condition resulting from exposure to a traumatic event. It is characterized by several debilitating…”
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An evaluation of aversive memory and hippocampal oxidative status in streptozotocin-induced diabetic rats treated with resveratrol
Published in Neuroscience letters (01-01-2017)“…•Diabetic rats exhibited normal freezing response in contextual fear conditioning.•Hippocampal oxidative status was unaltered in diabetic rats.•Resveratrol…”
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Neuroprotective effect of ACTH on collagenase-induced peri-intraventricular hemorrhage in newborn male rats
Published in Scientific reports (20-10-2020)“…Peri-intraventricular hemorrhage (PIVH) is a common and serious prematurity-related complication in neonates. Adrenocorticotropic hormone (ACTH) has…”
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Ketamine promotes increased freezing behavior in rats with experimental PTSD without changing brain glucose metabolism or BDNF
Published in Neuroscience letters (29-09-2017)“…•Ketamine increases freezing behavior in rats with experimental PTSD.•PTSD and ketamine treatment do not alter BDNF protein levels in rat brain.•PTSD and…”
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