Search Results - "Xavier, Fabiano E."

Therapeutic Potential of Phosphodiesterase Inhibitors for Endothelial Dysfunction- Related Diseases by Blanco-Rivero, Javier, Xavier, Fabiano E

“…Cardiovascular diseases (CVD) are considered a major health problem worldwide, being the main cause of mortality in developing and developed countries…”
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Biphasic Effect of Diabetes on Neuronal Nitric Oxide Release in Rat Mesenteric Arteries by Sastre, Esther, Caracuel, Laura, Blanco-Rivero, Javier, Callejo, María, Xavier, Fabiano E, Balfagón, Gloria

“…We analysed possible time-dependent changes in nitrergic perivascular innervation function from diabetic rats and mechanisms implicated. In endothelium-denuded…”
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Nitrergic perivascular innervation in health and diseases: Focus on vascular tone regulation by Xavier, Fabiano E.

“…For a long time, the vascular tone was considered to be regulated exclusively by tonic innervation of vasoconstrictor adrenergic nerves. However, accumulating…”
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Increased cyclooxygenase-2-derived prostanoids contributes to the hyperreactivity to noradrenaline in mesenteric resistance arteries from offspring of diabetic rats by Ramos-Alves, Fernanda E, de Queiroz, Diego B, Santos-Rocha, Juliana, Duarte, Gloria P, Xavier, Fabiano E

“…This study analyzed the effect of in utero exposure to maternal diabetes on contraction to noradrenaline in mesenteric resistance arteries (MRA) from adult…”
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Tranilast increases vasodilator response to acetylcholine in rat mesenteric resistance arteries through increased EDHF participation by Xavier, Fabiano E, Blanco-Rivero, Javier, Sastre, Esther, Caracuel, Laura, Callejo, María, Balfagón, Gloria

“…Tranilast, in addition to its capacity to inhibit mast cell degranulation, has other biological effects, including inhibition of reactive oxygen species,…”
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Opposite effect of mast cell stabilizers ketotifen and tranilast on the vasoconstrictor response to electrical field stimulation in rat mesenteric artery by Sastre, Esther, Caracuel, Laura, Xavier, Fabiano E, Balfagón, Gloria, Blanco-Rivero, Javier

“…We analyzed whether mast cell stabilization by either ketotifen or tranilast could alter either sympathetic or nitrergic innervation function in rat mesenteric…”
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Participation of prostacyclin in endothelial dysfunction induced by aldosterone in normotensive and hypertensive rats by Blanco-Rivero, Javier, Cachofeiro, Victoria, Lahera, Vicente, Aras-Lopez, Rosa, Márquez-Rodas, Iván, Salaices, Mercedes, Xavier, Fabiano E, Ferrer, Mercedes, Balfagón, Gloria

“…The aim of the present study was to analyze the possible involvement of vasoconstrictors prostanoids on the reduced endothelium-dependent relaxations produced…”
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Dexamethasone decreases neuronal nitric oxide release in mesenteric arteries from hypertensive rats through decreased protein kinase C activation by Aras-López, Rosa, Xavier, Fabiano E, Ferrer, Mercedes, Balfagón, Gloria

“…Neuronal NO plays a functional role in many vascular tissues, including MAs (mesenteric arteries). Glucocorticoids alter NO release from endothelium and the…”
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Aldosterone alters the participation of endothelial factors in noradrenaline vasoconstriction differently in resistance arteries from normotensive and hypertensive rats by Xavier, Fabiano E., Blanco-Rivero, Javier, Avendaño, María Soledad, Sastre, Esther, Yela, Rubén, Velázquez, Kyra, Salaíces, Mercedes, Balfagón, Gloria

“…This study analyzed the effect of aldosterone (0.05 mg/kg per day, 3 weeks) on vasoconstriction induced by noradrenaline in mesenteric resistance arteries from…”
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Dexamethasone decreases contraction to electrical field stimulation in mesenteric arteries from spontaneously hypertensive rats through decreases in thromboxane A2 release by Aras-Lopéz, Rosa, Blanco-Rivero, Javier, Xavier, Fabiano E, Salaices, Mercedes, Ferrer, Mercedes, Balfagón, Gloria

“…Glucocorticoids play a role in the control of vascular smooth muscle tone through the alteration of vasoconstrictor and vasodilator factor production. We…”
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Phosphodiesterase-3 inhibitor cilostazol reverses endothelial dysfunction with ageing in rat mesenteric resistance arteries by Moreira, Hicla S., Lima-Leal, Geórgia A., Santos-Rocha, Juliana, Gomes-Pereira, Leonardo, Duarte, Gloria P., Xavier, Fabiano E.

“…Ageing impairs endothelial function, which is considered a hallmark of the development of cardiovascular diseases in elderly. Cilostazol, a phosphodiesterase-3…”
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Oxidative stress induced by prenatal LPS leads to endothelial dysfunction and renal haemodynamic changes through angiotensin II/NADPH oxidase pathway: Prevention by early treatment with α-tocopherol by Vieira, Leucio D., Farias, Juliane S., de Queiroz, Diego B., Cabral, Edjair V., Lima-Filho, Manoel M., Sant'Helena, Bruna R.M., Aires, Regina S., Ribeiro, Valdilene S., Santos-Rocha, Juliana, Xavier, Fabiano E., Paixão, Ana D.

“…We investigated whether hypertension induced by maternal lipopolysaccharide (LPS) administration during gestation is linked to peripheral vascular and renal…”
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Maternal high-sodium intake affects the offspring’ vascular renin-angiotensin system promoting endothelial dysfunction in rats by Santos-Rocha, Juliana, Lima-Leal, Geórgia A., Moreira, Hicla S., Ramos-Alves, Fernanda E., de Sá, Francine G., Duarte, Gloria P., Xavier, Fabiano E.

“…Perinatal sodium overload induces endothelial dysfunction in adult offspring, but the underlying mechanisms are not fully known. The involvement of tissue…”
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Simultaneous inhibition of TXA(2) and PGI(2) synthesis increases NO release in mesenteric resistance arteries from cirrhotic rats by Xavier, Fabiano E, Blanco-Rivero, Javier, Sastre, Esther, Badimón, Lina, Balfagón, Gloria

“…Our present study examines, in mesenteric resistance arteries, possible vasodilation alterations, and the role of NO and COX (cyclo-oxygenase) derivatives, in…”
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Time-dependent increases in ouabain-sensitive Na +, K +-ATPase activity in aortas from diabetic rats: The role of prostanoids and protein kinase C by Gallo, Luana C., Davel, Ana Paula C., Xavier, Fabiano E., Rossoni, Luciana V.

“…Na +, K +-ATPase activity contributes to the regulation of vascular contractility and it has been suggested that vascular Na +, K +-ATPase activity may be…”
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Alterations in structure and mechanics of resistance arteries from ouabain-induced hypertensive rats by Briones, Ana M, Xavier, Fabiano E, Arribas, Silvia M, González, M Carmen, Rossoni, Luciana V, Alonso, María J, Salaices, Mercedes

“…We have previously described that chronic administration of ouabain induces hypertension and functional alterations in mesenteric resistance arteries. The aim…”
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Chronic ouabain treatment exacerbates blood pressure elevation in spontaneously hypertensive rats: the role of vascular mechanisms by Xavier, Fabiano E, Davel, Ana Paula C, Fukuda, Lívia E, Rossoni, Luciana V

“…OBJECTIVEHypertensive rats are more sensitive to the pressor effects of acute ouabain than normotensive rats. We analyzed the effect of chronic ouabain (∼8.0…”
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Vascular effects of the Mangifera indica L. extract (Vimang) by Beltrán, Amada E., Alvarez, Yolanda, Xavier, Fabiano E., Hernanz, Raquel, Rodriguez, Janet, Núñez, Alberto J., Alonso, María J., Salaices, Mercedes

“…The effects of the Mangiferia indica L. (Vimang) extract, and mangiferin (a C-glucosylxanthone of Vimang) on the inducible isoforms of cyclooxygenase…”
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Ouabain‐induced hypertension alters the participation of endothelial factors in α‐adrenergic responses differently in rat resistance and conductance mesenteric arteries by Xavier, Fabiano E, Rossoni, Luciana V, Alonso, María J, Balfagón, Gloria, Vassallo, Dalton V, Salaices, Mercedes

“…This study compares the role of endothelial factors in α‐adrenoceptor contractile responses in mesenteric resistance (MRA) and superior (SMA) mesenteric…”
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Long-term fenofibrate treatment impairs endothelium-dependent dilation to acetylcholine by altering the cyclooxygenase pathway by Blanco-Rivero, Javier, Márquez-Rodas, Iván, Xavier, Fabiano E, Aras-López, Rosa, Arroyo-Villa, Irene, Ferrer, Mercedes, Balfagón, Gloria

“…Experimental studies and opinion articles emphasize that cardiovascular alterations associated with ageing can be improved by the long-term use of…”
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