Search Results - "Xanthopoulos, K G"
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Molecular Cloning, Sequence, and Expression Patterns of the Human Gene Encoding CCAAT/Enhancer Binding Protein α (C/EBPα)
Published in Biochemical and biophysical research communications (04-10-1995)“…The human gene encoding the transcription factor C/EBPα was isolated from an umbilical cord genomic library screened by low stringency hybridization. Two…”
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Enhancement of antitumor immune response in glioma models in mice by genetically modified dendritic cells pulsed with Semliki Forest virus-mediated complementary DNA
Published in Journal of neurosurgery (01-03-2001)“…The aim of this study was to further investigate dendritic cell (DC)-based immunotherapy for malignant glioma to improve its therapeutic efficacy. Dendritic…”
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A Novel Human CCAAT/Enhancer Binding Protein Gene, C/EBPϵ, Is Expressed in Cells of Lymphoid and Myeloid Lineages and Is Localized on Chromosome 14q11.2 Close to the T-Cell Receptor α/δ Locus
Published in Genomics (San Diego, Calif.) (01-07-1996)“…Members of the C/EBP family of transcriptional factors have been implicated in the regulation of genes in a variety of tissues. We report here the isolation…”
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4
A direct role for C/EBP and the AP-I-binding site in gene expression linked to adipocyte differentiation
Published in Molecular and Cellular Biology (01-12-1989)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Different Tissue Transcription Patterns of Genes for HNF-1, C/EBP, HNF-3, and HNF-4, Protein Factors that Govern Liver-Specific Transcription
Published in Proceedings of the National Academy of Sciences - PNAS (01-05-1991)“…The transcription factors that act in hepatocyte-specific gene expression include proteins that are present mainly in liver cells (HNF-1/LFB1, C/EBP, HNF-3,…”
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Targeted expression of Cre recombinase to adipose tissue of transgenic mice directs adipose-specific excision of loxP-flanked gene segments
Published in Nucleic acids research (15-06-1997)“…Functional analysis of mammalian genes relies, in part, on targeted mutations generated by homologous recombination in mice. We have developed a strategy for…”
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Biological Role of the CCAAT/Enhancer-binding Protein Family of Transcription Factors
Published in The Journal of biological chemistry (30-10-1998)“…CCAAT/enhancer-binding proteins (C/EBPs) comprise a family of transcription factors that are critical for normal cellular differentiation and function in a…”
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CCAAT/enhancer binding proteins are critical components of the transcriptional regulation of hematopoiesis (Review)
Published in International journal of molecular medicine (01-01-1998)“…The coordinated expression of four different CCAAT/enhancer binding proteins (C/EBPs), C/EBPalpha, C/EBPbeta, C/EBPdelta, and C/EBPepsilon constitutes a…”
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High level activity of the mouse CCAAT/enhancer binding protein (C/EBPα) gene promoter involves autoregulation and several ubiquitous transcription factors
Published in Nucleic acids research (25-04-1993)“…The promoter region of the mouse CCAAT-Enhancer Binding Protein (C/EBPα) gene Is capable of directing high levels of expression of reporter constructs In…”
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10
Suicide Gene Therapy for Plasma Cell Tumors
Published in Blood (15-09-1996)“…Suicide gene therapy for plasma cell tumors was attempted in severe combined immunodeficient (SCID) mice injected with human myeloma cell lines. Initially, a…”
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Cell-Specific Transcriptional Control of the Mouse DNA-Binding Protein mC/EBP
Published in Proceedings of the National Academy of Sciences - PNAS (01-06-1989)“…The mRNA encoding the mouse homolog of C/EBP, a rat DNA-binding protein that participates in activating a number of genes in hepatocytes, is present in liver…”
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12
A Liver-Specific DNA-Binding Protein Recognizes Multiple Nucleotide Sites in Regulatory Regions of Transthyretin, α 1-antitrypsin, Albumin, and Simian Virus 40 Genes
Published in Proceedings of the National Academy of Sciences - PNAS (01-06-1988)“…Double-stranded oligodeoxynucleotides that represent protein binding sites in the regulatory regions of the mouse genes encoding transthyretin (TTR) and α…”
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Impaired Granulopoiesis, Myelodysplasia, and Early Lethality in CCAAT/Enhancer Binding Protein ε -deficient Mice
Published in Proceedings of the National Academy of Sciences - PNAS (25-11-1997)“…Polymorphonuclear leukocytes are essential for host defense to infectious diseases. CCAAT/enhancer binding protein ε (C/EBPε ) is preferentially expressed in…”
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Molecular cloning, cDNA sequencing, and chemical synthesis of cecropin B from Hyalophora cecropia
Published in Proceedings of the National Academy of Sciences - PNAS (01-04-1985)“…Two cDNA clones containing coding information for cecropin B from the Cecropia moth (Hyalophora cecropia) were identified by means of a synthetic probe…”
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Differential adrenergic regulation of C/EBPα and C/EBPβ in brown adipose tissue
Published in FEBS letters (08-03-1993)“…We investigated the regulation of the expression of two members of the C/EBP family of transcriptional activators, C/EBPα and C/EBPβ, in brown adipose tissue…”
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CCAAT/enhancer binding protein epsilon is critical for effective neutrophil-mediated response to inflammatory challenge
Published in Blood (01-05-1999)“…Targeted mutation of CCAAT/enhancer binding protein (C/EBP) epsilon in mice results in early death, primarily due to spontaneous infection with Pseudomonas…”
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Generation of a conditionally neo(r)-containing retroviral producer cell line: effects of neo(r) on retroviral titer and transgene expression
Published in Gene therapy (01-05-1998)“…We have developed a method for generating high-titer retroviral producer cell lines conditionally containing a neomycin resistance gene (neo(r)) based on the…”
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Increased hepatic cell proliferation and lung abnormalities in mice deficient in CCAAT/enhancer binding protein alpha
Published in The Journal of biological chemistry (1996)“…CCAAT/enhancer binding protein alpha (C/EBPalpha) is a transcription factor that has been implicated in the regulation of cell-specific gene expression mainly…”
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Analysis by in situ Hybridization of Cells Expressing mRNA for Interleukin 4 in the Developing Thymus and in Peripheral Lymphocytes from Mice
Published in Proceedings of the National Academy of Sciences - PNAS (01-01-1988)“…We have made use of RNA· RNA in situ hybridization to study the presence of cells producing mRNA for interleukin 4 (IL-4) in the developing thymus, spleen, and…”
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Gene regulation in rodent hepatocytes during development, differentiation and disease
Published in European journal of biochemistry (01-09-1993)“…The expression of genes in the liver is mostly controlled at the transcriptional level and depends on the regulatory interactions between cis‐acting sequences…”
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