Search Results - "XUEJING ZHU"
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Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy
Published in Cell death & disease (30-10-2021)“…Autophagy-mediated lipotoxicity plays a critical role in the progression of diabetic nephropathy (DN), but the precise mechanism is not fully understood…”
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2
Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis
Published in Redox biology (01-06-2018)“…NLRP3/IL-1β activation via thioredoxin (TRX)/thioredoxin-interacting protein (TXNIP) following mitochondria ROS (mtROS) overproduction plays a key role in…”
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3
A species-specific miRNA participates in biomineralization by targeting CDS regions of Prisilkin-39 and ACCBP in Pinctada fucata
Published in Scientific reports (02-06-2020)“…Biomineralization is a sophisticated biological process precisely regulated by multiple molecules and pathways. Accumulating miRNAs have been identified in…”
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4
TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease
Published in Frontiers in endocrinology (Lausanne) (19-09-2019)“…Gasdermin D (GSDMD) has been proven to be a key protein in the activation of pyroptosis. Pyroptosis of renal tubular epithelial cells contributes to the…”
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5
Rap1 Ameliorates Renal Tubular Injury in Diabetic Nephropathy
Published in Diabetes (New York, N.Y.) (01-04-2014)“…Rap1b ameliorates high glucose (HG)-induced mitochondrial dysfunction in tubular cells. However, its role and precise mechanism in diabetic nephropathy (DN) in…”
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6
Targeting the NLRP3 Inflammasome in Diabetic Nephropathy
Published in Current medicinal chemistry (01-01-2021)“…Diabetic nephropathy (DN) is one of the most common complications of diabetes and the main cause of end-stage renal disease (ESRD). The inflammatory response…”
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7
Normoalbuminuric diabetic kidney disease
Published in Frontiers of medicine (01-09-2017)“…Diabetic kidney disease (DKD) is one of the primary causes of end-stage renal disease (ESRD). Early diagnosis is very important in preventing the development…”
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Predictive value of sub classification of focal segmental glomerular sclerosis in Oxford classification of IgA nephropathy
Published in Annals of medicine (Helsinki) (01-01-2021)“…The Oxford classification of IgA nephropathy (IgAN) was revised in 2016 which lacked sufficient evidence for prognostic value of subclassification of focal…”
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9
Melatonin alleviates renal injury by activating mitophagy in diabetic nephropathy
Published in Frontiers in endocrinology (Lausanne) (05-08-2022)“…Diabetic nephropathy (DN) causes serious renal tubule and interstitial damage, but effective prevention and treatment measures are lacking. Abnormal mitophagy…”
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10
Effects of packaging materials on storage quality of peanut kernels
Published in PloS one (08-03-2018)“…In order to obtain optimum packaging materials for peanut kernels, the effects of four types of packaging materials on peanut storage quality (coat color, acid…”
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11
ER-Phagy: A New Regulator of ER Homeostasis
Published in Frontiers in cell and developmental biology (09-07-2021)“…The endoplasmic reticulum (ER) is one of the most important cellular organelles and is essential for cell homeostasis. Upon external stimulation, ER stress…”
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12
Bowman's capsule rupture and the Oxford MEST-C score in adult patients with Immunoglobulin a vasculitis nephritis: a single center experience
Published in Annals of medicine (Helsinki) (12-12-2023)“…BCR was associated with clinical manifestations and pathological changes in patients with IgAV-N, particularly crescents. The ISKDC classification was related…”
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13
Acute Kidney Injury after Multiple Cycles of Cisplatin Chemotherapy: A Nomogram for Risk Assessment
Published in Kidney & blood pressure research (01-01-2023)“…Abstract Introduction: Acute kidney injury (AKI) caused by cisplatin is common and has a higher incidence of multiple use, resulting in a poor short- and…”
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14
Left ventricular hypertrophy, carotid atherosclerosis, and cognitive impairment in peritoneal dialysis patients
Published in BMC cardiovascular disorders (09-03-2023)“…Left ventricular hypertrophy (LVH) and carotid atherosclerosis (CAS) have been identified as factors associated with cognitive impairment (CI) but have not…”
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15
Tubular atrophy/interstitial fibrosis scores of Oxford classification combinded with proteinuria level at biopsy provides earlier risk prediction in lgA nephropathy
Published in Scientific reports (24-04-2017)“…The predictive effect of combining MEST with clinical data at biopsy on renal survival outcomes has not been investigated in patients with IgA nephropathy…”
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16
p66Shc: A novel biomarker of tubular oxidative injury in patients with diabetic nephropathy
Published in Scientific reports (05-07-2016)“…Increased p66Shc expression has been associated with diabetic nephropathy (DN). However, whether p66Shc can serve as a potential biomarker for tubular…”
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17
Alpha-kinase1 promotes tubular injury and interstitial inflammation in diabetic nephropathy by canonical pyroptosis pathway
Published in Biological research (02-02-2023)“…Alpha-kinase 1 (ALPK1) is a master regulator in inflammation and has been proved to promote renal fibrosis by promoting the production of IL-1β in diabetic…”
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18
Immunofluorescence deposits in the mesangial area and glomerular capillary loops did not affect the prognosis of immunoglobulin a nephropathy except C1q:a single-center retrospective study
Published in BMC nephrology (29-01-2021)“…Immunoglobulin A nephropathy (IgAN) is identified as mesangial IgA deposition and is usually accompanied by other immunofluorescence deposits. The impact of…”
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Low-dose paclitaxel ameliorates fibrosis in the remnant kidney model by down-regulating miR-192
Published in The Journal of pathology (01-11-2011)“…Transforming growth factor (TGF)‐β has been shown to play a central role in the development of tubulointerstitial fibrosis, which can be corrected via…”
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Efficacy of corticosteroids in immunoglobulin A nephropathy with less than 25% crescents
Published in Clinical and experimental nephrology (01-01-2020)“…Background Crescent formation in immunoglobulin A nephropathy (IgAN) has been demonstrated to be a risk factor for worse outcomes. For IgAN patients with 0–25%…”
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