Search Results - "XU, R. H"

Pan-Asian adapted ESMO consensus guidelines for the management of patients with metastatic colorectal cancer: a JSMO–ESMO initiative endorsed by CSCO, KACO, MOS, SSO and TOS by Yoshino, T., Arnold, D., Taniguchi, H., Pentheroudakis, G., Yamazaki, K., Xu, R.-H., Kim, T.W., Ismail, F., Tan, I.B., Yeh, K.-H., Grothey, A., Zhang, S., Ahn, J.B., Mastura, M.Y., Chong, D., Chen, L.-T., Kopetz, S., Eguchi-Nakajima, T., Ebi, H., Ohtsu, A., Cervantes, A., Muro, K., Tabernero, J., Minami, H., Ciardiello, F., Douillard, J.-Y.

“…The most recent version of the European Society for Medical Oncology (ESMO) consensus guidelines for the treatment of patients with metastatic colorectal…”
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Glycolysis inhibition for anticancer treatment by Pelicano, H, Martin, D S, Xu, R-H, Huang, P

“…Most cancer cells exhibit increased glycolysis and use this metabolic pathway for generation of ATP as a main source of their energy supply. This phenomenon is…”
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ITD mutation in FLT3 tyrosine kinase promotes Warburg effect and renders therapeutic sensitivity to glycolytic inhibition by Ju, H-Q, Zhan, G, Huang, A, Sun, Y, Wen, S, Yang, J, Lu, W-h, Xu, R-h, Li, J, Li, Y, Garcia-Manero, G, Huang, P, Hu, Y

“…Internal tandem duplication (ITD) mutation in Fms-like tyrosine kinase 3 gene (FLT3/ITD) represents an unfavorable genetic change in acute myeloid leukemia…”
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Characteristic skin lesions of monkeypox by Zhang, L-W, Wu, J, Xu, R-H, Chen, T

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Disrupting G6PD-mediated Redox homeostasis enhances chemosensitivity in colorectal cancer by Ju, H-Q, Lu, Y-X, Wu, Q-N, Liu, J, Zeng, Z-L, Mo, H-Y, Chen, Y, Tian, T, Wang, Y, Kang, T-B, Xie, D, Zeng, M-S, Huang, P, Xu, R-H

“…Glucose-6-phosphate dehydrogenase (G6PD) is a key enzyme that generates NADPH to maintain reduced glutathione (GSH), which scavenges reactive oxygen species…”
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Metabolic regulation of cancer cell side population by glucose through activation of the Akt pathway by Liu, P-P, Liao, J, Tang, Z-J, Wu, W-J, Yang, J, Zeng, Z-L, Hu, Y, Wang, P, Ju, H-Q, Xu, R-H, Huang, P

“…Side population (SP) cells within tumors are a small fraction of cancer cells with stem-like properties that can be identified by flow cytometry analysis based…”
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Elimination of chronic lymphocytic leukemia cells in stromal microenvironment by targeting CPT with an antiangina drug perhexiline by Liu, P-P, Liu, J, Jiang, W-Q, Carew, J S, Ogasawara, M A, Pelicano, H, Croce, C M, Estrov, Z, Xu, R-H, Keating, M J, Huang, P

“…Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the western countries and is currently incurable due, in part, to difficulty in…”
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Validation of a nomogram for selecting patients for chemotherapy after D2 gastrectomy for cancer by Wang, Z.‐X., Li, G.‐X., Zhou, Z.‐W., Huang, Z.‐P., Wang, F., Xu, R.‐H.

“…Background According to some guidelines for the management of gastric cancer, adjuvant chemotherapy is recommended for patients with pT3–4 or node‐positive…”
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A systematic review and net meta-analysis of the effects of different warm-up methods on the acute effects of lower limb explosive strength by Li, F. Y, Guo, C. G, Li, H. S, Xu, H. R, Sun, P

“…Abstract Objective To evaluate the effects of different warm-up methods on the acute effect of lower limb explosive strength with the help of a reticulated…”
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Pan-Asian adapted ESMO Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with metastatic colorectal cancer by Yoshino, T., Cervantes, A., Bando, H., Martinelli, E., Oki, E., Xu, R.-H., Mulansari, N.A., Govind Babu, K., Lee, M.A., Tan, C.K., Cornelio, G., Chong, D.Q., Chen, L.-T., Tanasanvimon, S., Prasongsook, N., Yeh, K.-H., Chua, C., Sacdalan, M.D., Sow (Jenson), W.J., Kim, S.T., Chacko, R.T., Syaiful, R.A., Zhang, S.Z., Curigliano, G., Mishima, S., Nakamura, Y., Ebi, H., Sunakawa, Y., Takahashi, M., Baba, E., Peters, S., Ishioka, C., Pentheroudakis, G.

“…The European Society for Medical Oncology (ESMO) Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with metastatic colorectal…”
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Synergistic effect of targeting mTOR by rapamycin and depleting ATP by inhibition of glycolysis in lymphoma and leukemia cells by XU, R.-H, PELICANO, H, ZHANG, H, GILES, F. J, KEATING, M. J, HUANG, P

“…The mammalian target of rapamycin (mTOR) pathway plays important roles in regulating nutrient metabolism and promoting the growth and survival of cancer cells,…”
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miR-143 is involved in endothelial cell dysfunction through suppression of glycolysis and correlated with atherosclerotic plaques formation by Xu, R-H, Liu, B, Wu, J-D, Yan, Y-Y, Wang, J-N

“…Atherosclerosis is recognized as a chronic inflammatory disease leading to hardening of the vessel wall and narrowing of arteries. Endothelial cells (ECs)…”
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Health-related quality of life in patients with CLDN18.2-positive, locally advanced unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma: results from the SPOTLIGHT and GLOW clinical trials by Lordick, F., Van Cutsem, E., Shitara, K., Xu, R.-H., Ajani, J.A., Shah, M.A., Oh, M., Ganguli, A., Chang, L., Rhoten, S., Bhattacharya, P., Matsangou, M., Park, J.W., Pophale, R., Ranganath, R., Kang, Y.-K.

“…First-line zolbetuximab plus chemotherapy (SPOTLIGHT, mFOLFOX6; GLOW, CAPOX) significantly improved progression-free survival (PFS) and overall survival (OS)…”
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Olaparib plus paclitaxel sensitivity in biomarker subgroups of gastric cancer by Liu, Y.-Z., Hodgson, D., Locker, G., Lai, Z., Balcerzak, D., Sharpe, A., Barrett, J.C., Orr, M., Gutjahr, T.S., Dougherty, B., Roudier, M.P., Shi, X., Miller, R., Kim, W.H., Zeng, X., Ochiai, A., Im, S.-A., Xu, R.-H., Boku, N., Bang, Y.-J.

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Absolute lymphocyte count is a novel prognostic indicator in extranodal natural killer/T-cell lymphoma, nasal type by Huang, J.J., Jiang, W.Q., Lin, T.Y., Huang, Y., Xu, R.H., Huang, H.Q., Li, Z.M.

“…Background: Extranodal natural killer (NK)/T-cell lymphoma (ENKL) is a heterogeneous entity with poor survival, requiring risk stratification in affected…”
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Expression analysis of KAP9.2 and Hoxc13 genes during different cashmere growth stages by qRT-PCR method by Wang, X, Xu, H. R, Li, T, Qu, L, Zhao, Z. D, Zhang, Z. Y

“…Keratin-associated protein 9.2 (KAP9.2) and Homeobox C13 (Hoxc13) genes were chosen to study because of their biological functions involving hair formation…”
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Structural and electric properties of BaSn0.15Ti0.85O3 films on ITO/glass substrate by RF sputtering from powder target by Zhu, GS, Yan, DL, Xu, HR, Yu, AB

“…BaSn0.15Ti0.85O3 (BTS) ferroelectric thin films have been deposited on the tin-doped indium oxide (ITO)/glass substrate by RF sputtering from a powder target,…”
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Safety, efficacy and tumor mutational burden as a biomarker of overall survival benefit in chemo-refractory gastric cancer treated with toripalimab, a PD-1 antibody in phase Ib/II clinical trial NCT02915432 by Wang, F., Wei, X.L., Wang, F.H., Xu, N., Shen, L., Dai, G.H., Yuan, X.L., Chen, Y., Yang, S.J., Shi, J.H., Hu, X.C., Lin, X.Y., Zhang, Q.Y., Feng, J.F., Ba, Y., Liu, Y.P., Li, W., Shu, Y.Q., Jiang, Y., Li, Q., Wang, J.W., Wu, H., Feng, H., Yao, S., Xu, R.H.

“…High tumor mutational burden (TMB-H) is correlated with enhanced objective response rate (ORR) and progression-free survival (PFS) for certain cancers…”
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PTGS2 gene polymorphism -765G>C is associated with coronary artery disease: a meta-analysis by Xuan, C-L, Yan, W, Xuan, L, Xu, R-H

“…Previous studies focusing on the association of PTGS2 polymorphism -765G>C with coronary artery disease (CAD) have failed to reach the same conclusion. In the…”
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Increased mitochondrial biogenesis in primary leukemia cells: the role of endogenous nitric oxide and impact on sensitivity to fludarabine by CAREW, J. S, NAWROCKI, S. T, XU, R. H, DUNNER, K. JR, MCCONKEY, D. J, WIERDA, W. G, KEATING, M. J, HUANG, P

“…B cell chronic lymphocytic leukemia (CLL) is the most prevalent adult leukemia in the Western hemisphere, yet many biological and molecular features of the…”
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