Search Results - "XU, H. Howard"
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Acute intraperitoneal infection with a hypervirulent Acinetobacter baumannii isolate in mice
Published in Scientific reports (25-04-2019)“…Acinetobacter baumannii infection has become a major cause of healthcare-associated infection and a critical pathogen in the WHO antimicrobial resistance…”
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Potential Mechanisms of Mucin-Enhanced Acinetobacter baumannii Virulence in the Mouse Model of Intraperitoneal Infection
Published in Infection and immunity (01-11-2019)“…Porcine mucin has been commonly used to enhance the infectivity of bacterial pathogens, including , in animal models, but the mechanisms for enhancement by…”
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Development of LC-FAIMS-MS and its application to lipidomics study of Acinetobacter baumannii infection
Published in Journal of lipid research (01-11-2024)“…The recent advances in mass spectrometry (MS) technologies have enabled comprehensive lipid profiling in biological samples. However, the robustness and…”
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A Mouse Model of Acinetobacter baumannii-Associated Pneumonia Using a Clinically Isolated Hypervirulent Strain
Published in Antimicrobial Agents and Chemotherapy (01-08-2013)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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5
Complete genome sequence of hypervirulent and outbreak-associated Acinetobacter baumannii strain LAC-4: epidemiology, resistance genetic determinants and potential virulence factors
Published in Scientific reports (02-03-2015)“…Acinetobacter baumannii is an important human pathogen due to its multi-drug resistance. In this study, the genome of an ST10 outbreak A. baumannii isolate…”
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Phenotypic and Molecular Characterization of Acinetobacter baumannii Clinical Isolates from Nosocomial Outbreaks in Los Angeles County, California
Published in Journal of Clinical Microbiology (01-08-2008)“…Multidrug-resistant Acinetobacter baumannii strains have increasingly resulted in nosocomial outbreaks worldwide, leaving limited options for treatment. To…”
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7
A genome-wide inducible phenotypic screen identifies antisense RNA constructs silencing Escherichia coli essential genes
Published in FEMS microbiology letters (01-04-2012)“…Abstract Regulated antisense RNA (asRNA) expression has been employed successfully in Gram-positive bacteria for genome-wide essential gene identification and…”
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Molecular characterization and antimicrobial susceptibility of Acinetobacter baumannii isolates obtained from two hospital outbreaks in Los Angeles County, California, USA
Published in BMC infectious diseases (04-05-2016)“…Antibiotic resistant strains of Acinetobacter baumannii have been responsible for an increasing number of nosocomial infections including bacteremia and…”
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Discovery and characterization of BlsE, a radical S-adenosyl-L-methionine decarboxylase involved in the blasticidin S biosynthetic pathway
Published in PloS one (18-07-2013)“…BlsE, a predicted radical S-adenosyl-L-methionine (SAM) protein, was anaerobically purified and reconstituted in vitro to study its function in the blasticidin…”
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Synthesis, Characterization, and Antibacterial Activity of Structurally Complex 2-Acylated 2,3,1-Benzodiazaborines and Related Compounds
Published in Chemistry & biodiversity (01-09-2014)“…A set of 2‐acylated 2,3,1‐benzodiazaborines and some related boron heterocycles were synthesized, characterized, and tested for antibacterial activity against…”
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Phenotypic and Molecular Characterization of Acinetobacter Clinical Isolates Obtained from Inmates of California Correctional Facilities
Published in Journal of Clinical Microbiology (01-06-2011)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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12
Staphylococcus aureus TargetArray: Comprehensive Differential Essential Gene Expression as a Mechanistic Tool To Profile Antibacterials
Published in Antimicrobial Agents and Chemotherapy (01-09-2010)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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13
Two methionine aminopeptidases from Acinetobacter baumannii are functional enzymes
Published in Bioorganic & medicinal chemistry letters (01-06-2011)“…Drug resistance in Gram-negative bacteria, such as Acinetobacter baumannii, is emerging as a significant healthcare problem. New antibiotics with a novel…”
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14
SecReT6: a web-based resource for type VI secretion systems found in bacteria
Published in Environmental microbiology (01-07-2015)“…Summary SecReT6 (http://db‐mml.sjtu.edu.cn/SecReT6/) is an integrated database providing comprehensive information on type VI secretion systems (T6SSs) in…”
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15
Large-Scale Transposition Mutagenesis of Streptomyces coelicolor Identifies Hundreds of Genes Influencing Antibiotic Biosynthesis
Published in Applied and environmental microbiology (15-03-2017)“…Gram-positive bacteria produce thousands of bioactive secondary metabolites, including antibiotics. To systematically investigate genes affecting secondary…”
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The structure of the polysaccharide isolated from Acinetobacter baumannii strain LAC-4
Published in Carbohydrate research (22-05-2014)“…•Acinetobacter baumannii is an important human pathogen.•LPS is one of the bacterial virulence factors.•The structure of the polysaccharide part of the LPS…”
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17
Binding of α-synuclein with Fe(III) and with Fe(II) and biological implications of the resultant complexes
Published in Journal of inorganic biochemistry (01-04-2010)“…Parkinson’s disease (PD) is hallmarked by the abnormal intracellular inclusions (Lewy bodies or LBs) in dopaminergic cells. Amyloidogenic protein α-synuclein…”
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Intranasal immunization protects against Acinetobacter baumannii -associated pneumonia in mice
Published in Vaccine (01-01-2015)“…Highlights • Intranasal immunization protects mice against lethal respiratory Acinetobacter baumannii infection. • Immunization limits bacterial extrapulmonary…”
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Kinetic studies of inhibition of the amyloid beta (1–42) aggregation using a ferrocene-tagged β-sheet breaker peptide
Published in Analytical biochemistry (15-03-2013)“…The aggregation of amyloidogenic proteins/peptides has been closely linked to the neuropathology of several important neurological disorders. In Alzheimer’s…”
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Serum resistance, gallium nitrate tolerance and extrapulmonary dissemination are linked to heme consumption in a bacteremic strain of Acinetobacter baumannii
Published in International journal of medical microbiology (01-05-2014)“…Abstract Bacteremia caused by Acinetobacter baumannii is a highly lethal complication of hospital-acquired pneumonia. In the present study, we investigated the…”
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