Search Results - "XIU QUAN DU"
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Glucagon Receptor Knockout Prevents Insulin-Deficient Type 1 Diabetes in Mice
Published in Diabetes (New York, N.Y.) (01-02-2011)“…To determine the role of glucagon action in the metabolic phenotype of untreated insulin deficiency. We compared pertinent clinical and metabolic parameters in…”
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Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones
Published in Nature (London) (03-07-2014)“…The discovery of a selective, physiologically active inhibitor of insulin-degrading enzyme (IDE) illuminates the therapeutic potential of IDE inhibitors for…”
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Human cord plasma proteomic analysis reveals sexually dimorphic proteins associated with intrauterine growth restriction
Published in Proteomics (Weinheim) (01-04-2024)“…Intrauterine growth restriction (IUGR) is associated with increased risk of cardiometabolic disease later in life and has been shown to affect female and male…”
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Antioxidant Effects of N-Acetylcysteine Prevent Programmed Metabolic Disease in Mice
Published in Diabetes (New York, N.Y.) (01-08-2020)“…An adverse maternal in utero and lactation environment can program offspring for increased risk for metabolic disease. The aim of this study was to determine…”
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High-Fat Intake During Pregnancy and Lactation Exacerbates High-Fat Diet-Induced Complications in Male Offspring in Mice
Published in Endocrinology (Philadelphia) (01-10-2013)“…Altered fetal environments, such as a high-fat milieu, induce metabolic abnormalities in offspring. Different postnatal environments reveal the predisposition…”
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A selective neural network ensemble classification for incomplete data
Published in International journal of machine learning and cybernetics (01-10-2017)“…Neural network ensemble (NNE) is a simple and effective method to deal with incomplete data for classification. However, with the increase in the number of…”
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Hypoglycemia, hyperglucagonemia, and fetoplacental defects in glucagon receptor knockout mice: a role for glucagon action in pregnancy maintenance
Published in American journal of physiology: endocrinology and metabolism (01-03-2012)“…Alterations in insulin signaling as well as insulin action predispose to infertility as well as adverse pregnancy outcomes; however, little is known about the…”
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Pancreatic beta-cell overexpression of the glucagon receptor gene results in enhanced beta-cell function and mass
Published in American journal of physiology: endocrinology and metabolism (01-09-2009)“…In addition to its primary role in regulating glucose production from the liver, glucagon has many other actions, reflected by the wide tissue distribution of…”
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Hepatic response to restoration of GLUT4 in skeletal muscle of GLUT4 null mice
Published in American journal of physiology: endocrinology and metabolism (01-11-2007)“…Expression of GLUT4 in fast-twitch skeletal muscle fibers of GLUT4 null mice (G4-MO) normalized glucose uptake in muscle and restored peripheral insulin…”
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1653-P: Female Mice Are Protected from Deleterious Metabolic Programming Effects of a High-Fat Diet Fed during Pregnancy and Lactation
Published in Diabetes (New York, N.Y.) (01-06-2024)“…Obesity induced by a high fat (HF) diet during pregnancy (P) and lactation (L) shows a sexual dimorphic response in offspring. Studies reported a metabolic…”
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PERINATAL EXPOSURE TO HIGH DIETARY AGES DELAYS PUBERTY ONSET AND DISRUPTS FOLLICULOGENESIS IN FEMALE OFFSPRING
Published in Fertility and sterility (01-09-2020)Get full text
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Perinatal exposure to high dietary advanced glycation end products affects the reproductive system in female offspring in mice
Published in Molecular human reproduction (01-08-2020)“…Maternal nutrition and the intrauterine environment are important in determining susceptibility to reproductive and metabolic disturbances. Advanced glycation…”
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Monocyte chemotactic protein-1 plays a role in ovarian dysfunction related to high-fat diet-induced obesity
Published in Systems biology in reproductive medicine (03-07-2020)Get full text
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Monocyte chemotactic protein-1 plays a role in ovarian dysfunction related to high-fat diet-induced obesity
Published in Systems Biology in Reproductive Medicine (03-07-2020)“…Obesity, known to cause a systemic elevation in monocyte chemotactic protein-1 (MCP-1), adversely affects normal ovarian function. The aim of this study was to…”
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